Heart Failure Flashcards

1
Q

Defenition

A

failure of the heart to generate sufficient cardiac output to meet metabolic demands of the body

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2
Q

The four ways in which heart failure is classified

A
  1. Low-output HF vs High output HF
  2. Systolic vs Diastolic HF
  3. Acute vs Chronic HF
  4. New York Heart Association Classification of HF
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3
Q

How is Low-output HF vs High-output HF defined

A

Low-output HF
* cardiac output is reduced due to primary problem with the heart, so it cannot meed bodies needs

High-output HF
* heart that has normal cardiac output, but there is an increase in the bodies metabolic demands that the heart cannot meet

Low-output much more common

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4
Q

Causes of high-output HF - 6

AAPPTT mnemonic

A

Anaemia
Arteriovenous malformation
Paget’s disease
Pregnancy
Thyrotoxicosis
Thiamine deficiency (wet Beri-Beri)

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5
Q

Systolic vs Diastolic Heart failure definition

AKA reduced ejection fraction and preserved EF

A

Systolic dysfunction - ventricles can fill, but cannot contract sufficiently - reduced ejection fraction

Diastolic dysfunction - ventricles cannot relax and fill normally - preserved ejection fraction

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6
Q

Causes of systolic heart failure /HFrEF - 3

A
  • IHD
  • dilated cardiomyopathy
  • mycarditis
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7
Q

Causes of diastolic heart failure / HFpEF - 3

A
  • chronic HTN (bcos LV hypertrophy)
  • hypertrophoc cardiomyopathy
  • cardiac tamponade
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8
Q

New York Heart Association (NYHA) Classification of HF - 4

A

Class I - no limitation in physical activity, and activity does not cause undue fatigue, palpitation or dyspnoea.

Class II - slight limitation of physical activity, and comfort at rest. Ordinary physical activity causes fatigue, palpitation and/or dyspnoea.

Class III - marked limitation in physical activity, but comfort at rest. Minimal physical activity causes fatigue (less than ordinary).

Class IV - inability to carry on any physical activity without discomfort, with symptoms occurring at rest. If any activity takes place, discomfort increases.

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9
Q

Clinical features of left HF - 8

A

Causes pulmonary congestion (backup into lungs) and systemic hypoperfusion

  • SOB on exertion
  • Noctural dyspnoea
  • Orthopnoea
  • Pink frothy sputum
  • fine crackles on lung auscultation
  • cyanosis
  • long cap refil
  • hypotension
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10
Q

Clinical features of right HF - 6

A

Causes venous congestion and pulmonary hypoperfusion from reduced right heart output

  • Ankle swelling and abdo swelling
  • Anorexia and nausea
  • raised JVp
  • pitting oedema
  • hepatomegaly
  • transudative pleural effusion
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11
Q

Differentials of Heart failure - 4

A

COPD
ARDS
Renal failure
Liver failure

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12
Q

Investigations

A
  1. NT-pro-BNP Level (1st line)
  2. 12 lead ECG
  3. Bloods - U and E, LFTs, TFTs, lipid profile, glucose
  4. CXR
  5. Echo (looks at ejection fraction)
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13
Q

What are the ranges for BNP when measuring for HF

A
  • below 400 - HF not likely
  • 400-2000 - refer in less than 6 weeks
  • over 2000 - refer for 2 weeks
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14
Q

What are the EF percentages from an echo that differentiate between HFrEF and HFpEF?

A
  • if EF less than 40% - HFrEF (systolic dysfunction)
  • if EF is more than 40% - HFpEF (diastolic dysfunction)
  • EF 50%-70% with a normal BNP - normal
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15
Q

What are CXR findings of heart failure - ABCDEF

A

A: Alveolar oedema (with ‘batwing’ perihilar shadowing)
B: Kerley B lines (caused by interstitial oedema)
C: Cardiomegaly (cardiothoracic ratio >0.5)
D: upper lobe blood diversion
E: Pleural effusions (typically bilateral transudates)
F: Fluid in the horizontal fissure

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16
Q

Conservative management of heart failure - 5

A
  • weight loss
  • smoking cess
  • salt and fluid restriction
  • excercise based group rehab
  • annual flu and pneumococcal vaccine
17
Q

1st line medical Management of Heart failure - 6

A

1st line for all - Loop Diuretics e.g. fuorosemide

For HFpEF:
* manage co-morbidities
* cardiac rehab programme

For HFrEF
* ACEi and Beta blocker
* Consider ARB if intolerant to ACEi
* Consider hydralazine if intolerant to ACEi and ARB

18
Q

Medications used if symtoms persist after initial medical management of heart failure - 5

A
  • Aldosterone antagonists = spironolactone or eplerenone.
  • Hydralazine and a nitrate for Afro-Caribbean patients.

Others:
- Ivabradine if in sinus rhythm and impaired EF.
- Digoxin = useful in those with AF
- SGLT2 inhibitors - dapgliflozin

19
Q

What does the BASH mnemonic stand for

A

Medications that demonstrate mortality benefits in HFrEF:
Beta blockers
AceI
Sprionolactone
Hydralazine

20
Q

Surgical management of HF

A

Cardiac resynchronisation therapy

ICDS (implantable cardioverter defibrillator) are indicated if following criteria fulfilled:
QRS interval <120ms, high risk sudden cardiac death, NYHA class I-III
QRS interval 120-149ms without LBBB, NYHA class I-III
QRS interval 120-149ms with LBBB, NYHA class I