Heart failure Flashcards

1
Q

triggers of acute left ventricular failure?

A

iatrogenic (aggressive IV fluids in elderly with impaired left ventricular function)
MI
arrhythmias
sepsis
hypertensive emergency

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2
Q

Acute LVF causes?

A

type 1 respiratory failure, low oxygen without an increase in carbon dioxide

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3
Q

symptoms of lvf?

A

sob, looking unwell, cough with frothy white or pink sputum, sob worse when lying flat

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4
Q

signs of acute lvf?

A

tachycardia, raised resp rate, reduced oxygen sats, 3rd heart sound, bilateral basal crackles, hypotension, displaced apexbeat, cyanosis, elevated jvp

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5
Q

in right sided heart failure you would find?

A

raised jvp, peripheral oedema

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6
Q

why is BNP released?

A

released from ventricles when myocardium is stretched beyond the normal range.

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7
Q

action of BNP?

A

relax smooth muscle in blood vessels, diuretic to promote water excretion

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8
Q

BNP can be raised?

A

heart failure. >100mg/l
tachycardia
sepsis
PE
renal impairment
COPD

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9
Q

CXR for heart failure?

A

cardiomegaly >0.5
upper lobe venous diversion - increased diameter
bilateral pleural effusions
interlobar fissures fluid
kerley lines

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10
Q

management of acute LVF?

A

sit up
oxygen
diuretics iv furosemide
IV fluids stopped
underlying causes
monitor fluid balance

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11
Q

severe cases of LVF require?

A

Intravenous opiates, such as morphine, which act as vasodilators
Intravenous nitrates act as vasodilators, and may be considered in severe hypertension or acute coronary syndrome
Inotropes, such as dobutamine, to improve cardiac output
Vasopressors, such as noradrenalin, to improve blood pressure
Non‑invasive ventilation
Invasive ventilation (involving intubation and sedation)

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12
Q

de-novo heart failure is caused by?

A

increased cardiac filling pressures and myocardial dysfunction, due to ischaemia. this will cause reduced cardiac output and hypoperfusion, which will result in pulmonary oedema. other causes are viral myopathy, toxins, valve dysfunction

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13
Q

causes of decompensated heart failure?

A

ACS, acute arrhythmia, hypertensive crisis, valvular disease

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14
Q

when not to give vasodilators?

A

hypotension

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15
Q

when do vasodilators have a role?

A

concomitant myocardial ischaemia, sever hypertension, regurgitant aortic or mitral valve disease

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16
Q

how should patients with respiratory failure be treated?

A

CPAP

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17
Q

How to treat patients with cardiogenic shock, hypotension <85mmHg?

A

inotropic agents dobutamine (severe left ventricular dysfunction), vasopressor agents norepinephrine (if ionotropes dont work/ end organ hypoperfusion, mechanical circulatory assisstance intra aortic balloon counterpulsation

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18
Q

when should beta blockers be stopped in heart failure?

A

less than 50 beats per minute, second or 3rd degree atrioventricular block, shock

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19
Q

heart failure with reduced LVEF is?

A

<35 to 40%

20
Q

usually people with HF-rEF have?

A

systolic dysfunction whereas HF-pEF have diastolic dysfunction

21
Q

systolic dysfunction is?

A

ischaemic heart disease
dilated cardiomyopathy
myocarditis
arrhythmia

22
Q

diastolic dysfunction is due to?

A

hypertrophic obstructive cardiomyopathy
restrictive cardiomyopathy
cardiac tamponade
constrictive pericarditis

23
Q

left ventricular failure results in?

A

pulmonary oedema, dyspnoea, orthopnoea, paroxysmal nocturnal dyspnoea, bibasal fine crackles.

24
Q

right ventricular failure results in?

A

peripheral oedema
raised jvp
hepatomegaly
anorexia
weight gain

25
what is high output heart failure?
normal heart unable to pump enough blood to metabolic needs causes: pregnancy, thyrotoxicosis, thiamine deficiency, pagets disease, arteriovenous malformation, anaemia
26
causes of chronic heart failure?
ischaemic heart disease, valvular heart disease (aortic stenosis), HTN, arrhythmia, cardiomyopathy
27
presentation of chronic heart failure?
Breathlessness, worsened by exertion Cough, which may produce frothy white/pink sputum Orthopnoea, which is breathlessness when lying flat, relieved by sitting or standing (ask how many pillows they use) Paroxysmal nocturnal dyspnoea (more detail below) Peripheral oedema Fatigue
28
examination signs of chronic heart failure
tachycardia (raised heart rate) Tachypnoea (raised respiratory rate) Hypertension Murmurs on auscultation indicating valvular heart disease 3rd heart sound on auscultation Bilateral basal crackles (sounding “wet”) on auscultation of the lungs, indicating pulmonary oedema Raised jugular venous pressure (JVP), caused by a backlog on the right side of the heart, leading to an engorged internal jugular vein in the neck Peripheral oedema of the ankles, legs and sacrum
29
mechanisms of paroxysmal nocturnal dyspnoea?
1. fluid settles over large surface area causing breathlessness 2. respiratory centre less responsive, decreased resp rate - pulmonary congestion and hypoxia 3. less adrenalin- myocardium is relaxed, reduced output
30
New York Heart Association classification?
Class I: No limitation on activity Class II: Comfortable at rest but symptomatic with ordinary activities Class III: Comfortable at rest but symptomatic with any activity Class IV: Symptomatic at rest
31
referral to specialists depends on NT-proBNP?
400-2000ng/l- echo within 6 weeks above 2000ng/l- echo within 2 weeks
32
First line for chronic heart failure?
ABAL ACEi ramipril/ ARB Beta blocker bisoprolol Aldosterone antagonist when symtpoms not controlled with A/B spironolacotone/eplerenone Loop diuretics- furosemids/bumetanide
33
avoid ACEi in?
valvular heart disease
34
what cause electrolyte disturbances?
diuretics, aldosterone antagonist, ACEi
35
ACEi and aldosterone anatagonist cause?
hyperkalaemia
36
specialist treatment for HF?
SGLT2 inhibitor (e.g., dapagliflozin) Sacubitril with valsartan (brand name Entresto) Ivabradine Hydralazine with a nitrate Digoxin
37
implanatbale cardioverter defibrillators are used for?
shockable rhythms, ventricular tachycardia/ fibrillation previously
38
cardiac resynchronisation therapy?
EF less than 35%- biventricular triple chambers pacemaker
39
in chronic heart failure first line is always?
ACEi and BB
40
pneumococcal vaccine for those with asplenia, splenic dysfunction or CKD?
booster every 5 years
41
3rd line therapy for chronic heart failure?
ivabradine, sacubitril-valsartan, hydralazine in combination with nitrate, digoxin and cardiac resynchronisation therapy
42
criteria for ivabradine?
sinus rhythm>75/min LEVF less than 35
43
sacubitril valsartan criteria?
criteria: left ventricular fraction < 35% is considered in heart failure with reduced ejection fraction who are symptomatic on ACE inhibitors or ARBs should be initiated following ACEi or ARB wash-out period
44
digoxin is strongly indicated if?
coexistent AF
45
CRT indicated in
widened QRS left bundle branch block
46
hydralazine with nitrate in?
afro-carribean patients