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Disease and Therapeutics Final > Heart drugs > Flashcards

Heart drugs Flashcards

1
Q

competitive inhibitor of HMG-COA reductase

A

simvastatin

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2
Q

arteriole dilator

open K+ channels

A

hydrazaline

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3
Q

calcium channel blocker
angina prophylaxis
toxicity:cardiac depression, bradycardia-heart failure

A

diltiazem

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4
Q

selective B1 blocker

toxicity:asthma and acute heart failure

A

atemolol

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5
Q

positive ionotropic cardiac drug

side effect:premature depolarization

A

milrinone

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6
Q

B1 adenoceptor agonist

side effect: arrhythmias

A

dobutamine

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7
Q

metabolize to nitric acid

A

nitroglycerin

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8
Q

prolong refractory period in cardiac muscle

A

amiodarone

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9
Q

Na+ channel blocker

A

quinidine

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10
Q

ganglionic blocker

A

mecamylamine

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11
Q

inhibits intestinal sterol absorption, reduces LDL

A

exetimbe

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12
Q

increases lipolysis in liver and muscles

GI toxicity

A

fenobrate

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13
Q

aldosterone target, K+ sparing

acts on collecting tube

A

spironolactone

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14
Q

angiotensin-converting enzyme inhibitor (ACEI)

reduce salt and water

A

captopril

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15
Q

3 drugs that reduce atherosclerosis

A

fenobrate-a fibrate
exetimbe-a fibrate
simvastatin-a statin

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16
Q

4 drugs that relieve angina

A

hydralazine-casodilator
diltiazem-calcium channel blocker
nitroglycerine
atemolol-B1 blocker

17
Q

7 drugs that reduce hypertension

A 
Hydralazine-arteriole dilator 
Atemolol-B1 blocker
Mecamylamine-ganglionic blocker
Dobutamine- B1 agonist
Diltiazem-calcium channel blocker
Captopril-ACE inhibitor
Spironolactone-aldosterone target, K+ Sparing
18
Q

4 drugs that reduce cardiac arrhythmias

A

Quinidine-Na+ blocker
Atemolol- B1 blocker
Amiodarone-prolong refractory period in cardiac mus.
Nitroglycerine-metabolize to nitric oxide

19
Q

5 drugs that treat heart failure

A 
Hydrazaline-arteriole dilator
diltiazem-calcium channel blocker
dobutamine-b1 agonist
milrinone-positive ionotropic cardiac drug
captopril-ace inhibitor
20
Q

Ideal HDL

A

~60

anything lower is bad

21
Q

ideal LDL

A

<100
130-160 borderline high
>189 very high

22
Q

ideal triglicerides

A

<120

>200 high

23
Q

ideal total cholesterol is _____

high total cholesterol is _____

A

ideal: <200
high: >240

Disease and Therapeutics Final (9 decks)

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