Heart Diseases and Stroke Flashcards
the left atrium of the heart collects ____ blood that goes into left ventricle and pumped _____
oxygenated blood
pumped into body
______ blood comes back to heart in right atrium and pumped to _____
deoxygenated blood
pumped to lungs to collect oxygen
the pulmonary artery carries ____
deoxygenated blood
the left ventricle pumps oxygenated blood to the body via the ____
aorta
how is the arterial blood pressure regulated
regulated by the sympathetic nervous system, the renin-angiotensin-aldosterone system (RASS) and renal fucntion
____ of an artery would mean that the there is relaxing and widening of the blood vessel. There would be ____ resistance and ___ blood pressure. ____ is the opposite
vasodilation
there would be less resistance and less blood pressure
Vasoconstriction is the opposite
the Framingham Risk Scores are not available for ____ why?
80 years old or older
we have to consider that if a patient enters in 80 -> less benefit in making dietary changes at that point [life expectancy is reduced], there are more risks when restricting their diet
why does CVD risk increases with menopause
decline in estrogen, believed to have a positive effect on the inner layer of artery wall, helping to keep blood vessels flexible
what are the physiological changes in women post-menopause
- average age 51-55yo (induced at younger age in women who have had a hysterectomy)
- BP tends to increase
- LDL-c tends to increase
- HDL declines or remains the same
- TG tend to increase
Adults with ___ are two to four times more likely to die from heart disease than adults without
diabetes
what is ischemia?
when blood supply is inadequate and tissues are not getting enough oxygen
what causes a myocardial infarction (MI) aka Heart attack?
a blockage in one of the arteries feeding the muscle of the hearts -> ischemic section
what are the symptoms felt by a men experiencing a heart attack
- Acute chest pain
- shortness of break
- pain or discomfort in the jaw, neck, back, arm, or shoulder
what are the symptoms felt by a women experiencing a heart attack
- feeling NAUSEOUS, light-headed, unusually tired
- chest pain
- shortness of break
- pain or discomfort in the jaw, neck, back, arm, or shoulder
which are the tests to diagnose a myocardial infarction
- Electrocardiogram (EKG)
- Echocardiogram (Echo)
- Exercise stress test (treadmill test)
what does the electrocardiogram EKG measure?
measures heart’s electrical activity
what does the echocardiogram measure?
measures how well the heart pumps
what does the exercise stress test measure?
see how well the heart functions when it’s working hard
stable angina
angina pain develops when there is increased demand in the settling of a stable atherosclerotic plaque. The vessel is unable to dilate enough to allow adequate blood flow to meet the myocardial demand
unstable angina
the plaque ruptures and a thrombus forms around the ruptured plaque causing partial occlusion of the vessel. Angina pain occurs at rest or progresses rapidly over a short period of time
NSTEMI
during an NSTEMI, the plaque rupture and thrombus formation causes partial occlusion to the vessel that results in injury and infarct to the subendocardial myocardium
STEMI
A STEMI is characterized by COMPLETE occlusion of the blood vessel lumen, resulting in transmural injury and infarct to the myocardium which is reflected by EKG changes and a rise in TROPONINS
what is the most sensitive and specific test for myocardial damage? why?
Troponin levels because it has increase specificity compared with Creatine Kinase-MB + peak at 12hrs
what are the three biomarkers that can be measured to evaluate degree of damage during MI
- troponin
- creatine kinase (CK-MB) test
- lactate dehydrogenase (LDH)
what is thrombolysis
a procedure post MI consisting in delivering medication through a catheter in aim to dissolve clots in coronary arteries. Usually within 3hrs of the heart attack