Heart and Blood Vessels Flashcards

1
Q

What are the structures of the heart?

A
  • Vena cava.
  • Pulmonary artery.
  • Pulmonary vein.
  • Right atrium.
  • Atrioventricular valves.
  • Right ventricle.
  • Apex.
  • Left ventricle.
  • Left atrium.
  • Aorta.
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2
Q

What is the pulmonary circuit?

A

The right side of the heart sends deoxygenated blood from the body along the pulmonary artery to the lungs.

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3
Q

What is the system circuit?

A

The pump on the left side sends oxygenated blood from the lungs along the aorta to the rest of the body.

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4
Q

What is oxygenated and deoxygenated blood?

A
  • High in oxygen concentration and low in carbon dioxide concentration.
  • Low in oxygen concentration and high in carbon dioxide concentration.
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5
Q

Why is it an advantage for the human heart to have two separate pumps?

A
  • The right hand side generates pressure to send blood through the lungs where pressure drops.
  • When it is returned to the left side of the heart, it generates more pressure so the blood can travel around the body at a fast enough rate to generate a high metabolic rate.
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6
Q

What do coronary arteries do?

A

Deliver oxygenated blood to the cardiac muscle that makes up the walls of the heart.

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7
Q

Why does the cardiac muscle need a rich supply of blood?

A

It needs a good supply of oxygen and glucose for a hugh rate of aerobic respiration to produce lots of ATP for heart muscle contraction.

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8
Q

Explain the structure of the heart.

A
  • Atria are thin wall add and receive blood from the veins.
  • Blood from the vena cava flows into the right atrium while blood from the pulmonary veins flows into the left atrium.
  • Atria contract and blood passes through atrioventricular valves into the thicker walled ventricles.
  • Ventricles contract and blood passes up through the the open semi-lunar valves.
  • Right ventricle: blood passes into the pulmonary artery and then onto the lungs.
  • Left ventricle: blood passes into aorta and from there to the rest of the body.
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9
Q

What is the description and role of the septum?

A

The two chambers on the left side of the heart are completely separated from those on the right side by a wall of muscle called the septum.

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10
Q

What is the description and role of atrioventricular valves?

A
  • Prevent back flow of blood when they close.
  • Atrioventricular valves prevent back flow from ventricles to atria.
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11
Q

What is the description and role of semi-lunar valves?

A
  • Prevent backflow of blood when they close.
  • Semi-lunar valves prevent back flow from arteries to ventricles.
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12
Q

What is the description and role of tendinous cords?

A
  • Inelastic connective tissue attached to the atrioventricular valves.
  • Prevent the valves from inverting.
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13
Q

Why are the walls of the left ventricle thicker than those of the right?

A

They have thicker muscle so contract with greater force creating enough pressure to pump blood into the aorta and around the body.

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14
Q

What is the cardiac cycle?

A

• Diastole:
- The heart muscle relaxes.

• Atrial systole:
- Blood fills the atria from the vena cava and pulmonary vein.
- The atrial muscle contracts, increasing the pressure above that of the ventricles.
- This forces the atrioventricular valves to open and blood flows into the ventricles.

• Ventricular systole:
- The ventricle muscles contract.
- The volume of the ventricle decreases, increasing the pressure.
- This causes the atrioventricular valves to close as pressure is greater in ventricles than atria.
- The blood is pushed upwards, towards the arteries at the top of the heart.
- The semi-lunar valves have an en and blood flows into the aorta and pulmonary artery as pressure is greater in ventricles than arteries.

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15
Q

How is the cardiac cycle controlled?

A
  • A wave of electrical impulses is sent out from the sinoatrial node.
  • It spreads across both atria, causing them to contract.
  • The impulses reach the atrioventricular node where it is delayed.
  • This delay allows the atria to fully empty, and the ventricles to fill with blood before the ventricles contract.
  • The impulses are then transmitted down to the ventricles by the Bundle of His. This contains specialised conducting tissue called purkyne fibres.
  • The impulses spread up the ventricle wall from the base via purkyne fibres, causing the ventricles to contract from the base up.
  • Blood is forced up into the arteries.
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16
Q

What is the equation for cardiac output?

A

Cardiac output (dm^3 min^-1) = Stroke volume (cm^3) X Heart rate (bpm)

17
Q

What is the advantage of increasing cardiac output during exercise?

A
  • Allows more glucose and oxygen to be delivered to working muscles.
  • Allows a higher rate of aerobic respiration and more ATP produced.
18
Q

What is the structure of the arteries?

A
  • The wall is thick to withstand the high pressure of blood.
  • The thick middle coat contains many elastic fibres.
  • Allowing them to stretch during systole and recoil during diastole to maintain blood pressure and smoothes pressure.
  • The lumen is relatively small.
19
Q

What is the structure of arterioles?

A
  • Lots of muscle tissue.
  • Thinner than arteries.
  • Have an inner coat of a single layer of endothelium - reduces friction.
  • The muscle can contract, narrowing the diameter of the lumen (vasoconstriction).
  • The muscle can relax, to widen the lumen diameter (vasodilation).
20
Q

What is the structure of the veins?

A
  • Three layers, but the middle coat contains far fewer elastic or muscle fibres than arteries.
  • Walls are very thin.
  • Have valves.
  • Lumen is relatively large.
21
Q

What is the structure of the capillaries?

A
  • Rate of blood flow is reduced allowing more time for diffusion/exchange.
  • Single layer of squamous endothelial cells, providing a short diffusion pathway.
  • Tiny pores between the cells in the wall - so highly permeable.
  • Small size and large number in total provides a large surface area to volume ratio.
22
Q

What does blood plasma transport?

A
  • Carbon dioxide from the organs to the lungs.
  • Soluble products of digestion from the small intestine to other organs.
  • Urea from the liver to the kidneys.
23
Q

What are the adaptations of red blood cells?

A
  • Very small so there is a short diffusion pathway and had large surface area to volume ratio.
  • It has a biconcave disc that increases the surface area to volume ratio. The ‘dent’ also provides a shorter diffusion.
  • No organelles so it can carry more haemoglobin.
24
Q

How is tissue fluid formed and returned?

A
  • At the arteriole end of the capillary, there is high hydrostatic pressure due to the contraction of the left ventricle.
  • Water, ions and small molecules are forced out of the blood into the spaces between the cells. This is now tissue fluid.
  • Loss of fluid from the blood leads to a fall in hydrostatic blood pressure.
  • Soluble plasma proteins remain in the blood so some of the water re-enters the capillary by osmosis down a water potential gradient.
  • Excess tissue fluid is drained away from the cells by lymph vessels and returned to the circulation near the heart.
25
What is the function of haemoglobin?
- Has a high affinity for oxygen and readily loads oxygen where oxygen concentrations are high. - Unloads oxygen where oxygen concentrations reach a low level.
26
How does co-operative binding work?
- The binding of the first haem group with an oxygen molecule changes the quaternary structure and shape of the haemoglobin molecule. - This uncovers the second haem group making it easier for oxygen to bind to, thus increasing the affinity. - This increases affinity of the third haem group for oxygen and so on. - This effect explains why the oxygen dissociation curve has a sigmoidal shape.
27
What is the significance of the Bohr shift?
- During exercise, tissues have a greater demand for oxygen for aerobic respiration. - Bohr shift occurs to the right. - Haemoglobin unloads more oxygen to the respiring tissues for respiration, allowing for increased aerobic respiration rates.
28
Explain what high affinity is in haemoglobin.
- Usually in organisms that live in low partial pressure of oxygen environments such as at high altitudes. - Haemoglobin loads oxygen more readily in lungs. - Curve shifted to the left. - Haemoglobin is more saturated at any given partial pressure of oxygen. - E.g. lugworm.
29
Explain what low affinity is in haemoglobin.
- Usually in organisms that have high metabolic rates. - Haemoglobin unloads oxygen more readily at tissues for respiration. - Curve shifted to the right. - Haemoglobin has lower saturation at any given partial pressure of oxygen. - E.g. shrew.