Heart Flashcards
What is the thoracic cage made from…
12 vertebrae /IVD
12 pairs of ribs/costal cartilages
Sternum
What comprises the sternum?
Manubrium
Body
Xiphoid Process (T9)
What is the sternal angle of Louis?
Manubriosternal junction T4/T5 IVD level - articulates at rib 2 - bifurcation of the trachea - arch of aorta
How are intercostal spaces arranged?
Numbered according to the superior rib
What is the superior thoracic aperture?
Superior opening of the thoracic cage
- esophagus
- trachea
- neurovasculature
Thoracic Outlet Syndrome = structures affected by the obstruction of superior thoracic artery
What is the inferior thoracic aperture?
Bordered by..
- T12
- ribs 11-12
- costal cartilages 7-10
- xiphoid process at T9
Covered by diaphragm
Where is the caval opening of the inferior thoracic aperture?
IVC
T8
What is the esophageal hiatus?
vagus nerve CN 10
Esophagus
T10
What is the aortic hiatus?
Aorta
Azygous
Thoracic duct
T12
What is the mediastinum?
Houses the thoracic structures, excepts for the lungs/pleura
- fatty/loose connective tissue = facilitates movement
- becomes less flexible with age and repair
What does widening of the mediastinum indicate?
Indicative of the laceration of the great vessels, lymphoma, cardiac hypertrophy
What connects the superior mediastinum and inferior mediastinum?
Transverse thoracic plane
What’s the pericardium?
Middle mediastinum
Outer fibrous
Inner serous
What is the outer fibrous pericardium?
Thick, inelastic
Attached to central tendon/sternum
What is the inner serous pericardium?
Mesothelioma with connective tissue
Contains the:
- parietal pericardium
- visceral pericardium: epicardium/covers the heart
What is the pericardial cavity?
In between the parietal and visceral pericardium
Contains serous fluid
Pericarditis=inflammation of the pericardium
What is the duodenalojejunum junction?
Where the duodenum emerges from behind the peritoneum
On the right side of the abdominal cavity
What does the superior mesenteric artery branch to?
Right colic artery -> ascending colon
Jejunal arteries
Ileal arteries - - > make up the vasa recta, which in turn make up the intestinal wall
Ileocolic Artery - supplies the ileocolic junction
What does the middle colic artery supply?
The transverse colon
What is the first portion of the colon/ascending colon
Cecum
Attaches to ileum and the veriform appendix (found just posterior)
What is the second portion of the colon?
Ascending colon Right colic/hepatic flexure Transverse Colon Left colic/splenic flexure Descending colon Sigmoid Colon Sigmoid Mesecolon - mesenteric that connects portions of the sigmoid colon
Where do the preganglionic sympathetic neurons come for heart?
IMLCC T1-T4
Where do the postganglionic neurons for heart innervation come from?
They exit the sympathetic chain to mix into the cardiac plexus before entering the heart tissue.
What does sympathetic innervation to the heart cause?
Increases rate/force of contraction by…
- increasing the activity of SA/AV nodes
- vasodilating the coronary vessels (RCA, LCA)
Where does pregaglionic neurons in PARASYMPATHETIC to heart come from?
Vargas nuclei in the brain stem, these are parasympathetic branches of the vagus nerve
- they synapse in the cardiac plexus or the heart tissue
What does PARASYMPATHETIC innervation to heart cause?
Decreases the rate/force of contraction by…
- decreasing the activity of SA and AV nodes
- vasoconstriction get the coronary vessels
What is preganglionic sympathetic innervation to the lungs?
IMLCC T1-T4/T5
What is postganglionic sympathetic innervation to lungs?
Will exit the sympathetic chain medically as cervical/thoracic sympathetic nerves
Will mix with pulmonary plexus before following the bronchi into lung tissue
What does sympathetic innervation to the lungs cause?
Bronchodilation
Vasoconstriction
Inhibition of glandular secretions
What does parasympathetic innervation to lungs cause?
Bronchoconstriction
What else does parasympathetic innervation to lungs cause?
Vasodilation of blood vessels
Where do preganglionic neurons in parasympathetic division to lungs come from?
Vagal nuclei in the brainstem
- enter pulmonary plexus
- synapse on bronchi
What is myenteric plexus responsible for?
Motility in ENS
What is the submucosal plexus for?
Blood flow and secretions
Where does sympathetic innervation to abdomen come from?
IMLCC T5-L2
- exit the sympathetic chain on splanchnic nerves, which then synapse on collateral ganglia to innervate the abdomen
What do the greater splanchnic sympathetic nerves innervate?
T5-T9
Foregut/liver/gallbladder/pancreas
Greater splanchnic nerve projects to the celiac ganglion -> synapses on post-ganglionic neurons
What nerve fibers parasympathetically innervate the foregut/liver/pancreas/gallbladder?
Anterior and Posterior Vagal Trunk
Post-ganglionic neurons lie at the viscera
What sympathetic nerves innervate the hindgut?
L1-L2
- exit as lumbar splanchnic nerves
> inferior mesenteric ganglion
> postganglionic follows the blood supply of the IMA to the viscera
What parasympathetic nerves innervate the hindgut?
Preganglionic S2-S4
- pelvic splanchnic nerves -> inferior hypogastric -> rectal plexus ->viscera
Causes:
- vasodilation
- secretormotor to the GI mucosa
- motor to the GI musculature
What are the sympathetic innervations to the kidney?
T12
Least Splanchnic Nerve
> aorticorenal plexus
> post-ganglionic synapse and follows blood supply to kidney
Sympathetic:
- vasoconstriction
- decreases urine production
What are the sympathetic innervation to the midgut?
T10-T11
Lesser Splanchnic Nerve
> Superior Mesenteric Ganglion
> postganglionic fibers follow the blood supply
Vasoconstriction
Inhibits GI musculature
What provides sympathetic innervation to the adrenal gland?
Greater splanchnic nerve (T5-T8) -> celiac ganglion
Pre-ganglionic = medulla cells (chromaffin) - synapse on cells and release NE/Epi Post-ganglionic = blood vessels
What is the parasympathetic innervation to the midgut?
Vagal nuclei in the brainstem
What is the sympathetic preganglionic cell bodies?
T1-L2/L3
What are the preganglionic parasympathetic cell bodies?
CN X = thorax/abdomen
Abdomen/Pelvis = S2-S4
What is the white rami?
Preganglionic sympathetic axons
What is the grey rami?
Postganglionic sympathetic axons
What does vagal nerve of parasympathetic nervous system innervate?
Thorax and abdomen
Enters..
- esophageal plexus, forms an anterior/posterior vagal trunk before entering the abdomen
What is parasympathetic innveration?
Vagus Nerve (CN X)
Pelvic Splanchnic (IMLCC S2-S4) - projects to inferior hypogastric plexus to supply parasympathetic innervation to the gut
What is referred pain?
Inability to distinguish between visceral and somatic sensory distribution
- referred pain from heart will result in pain of T1-T4 dermatologist of the chest wall and medial arm
Endocardium
Lines the blood filled chambers
Myocardium
Thick, middle layer
Myocytes for contraction
Epicardium
Thin, external layer
Connective tissue, coronary arteries, mesothelioma
Hemopericardium
Blood into the pericardial cavity
Cardiac Tamponade
Compression on heart
In cardiac tamponade, what is presentation?
Face and neck swell due to impeded venous return to the heart
Where does pericardiocentesis occur?
In cardiac notch
- needle inserted superoposteriorly at infrasternal angle, at 5/6 LICS
What are the sequence of layers penetrated in pericardiocentesis?
AFPP
A- anterior body wall
F-fibrous pericardium
P-parietal layer of serous pericardium
P-pericardial cavity
What are the two pericardial sinuses?
Transverse sinus: horizontal gap, anterior to SVC, posterior to aorta-pulm trunk
Oblique sinus: under the apex
What is the base of the heart?
Posterior heart
Left atrium
Includes…
- proximal parts of the 4 pulmonary veins that empty into LA
(The RA and SVC/IVC form a small part of the heart
Where does the esophagus lie?
Posterior to the base of the heart
Vertebral bodies lie posterior to the esophagus
Where is the heart located?
T5-T8 = supine position
T6-T9 = standing position
What does the apex consist of?
Left ventricle
Left tip of the LV
- projects anteriorly and left
5th LICS at the MCL
What is the apex beat?
5th LICS at MCL
During auscultation, listen for sounds of the mitral valve
What blood flows into the RA?
Coronary sinus
SVC
IVC
Where is the sternocostal/anterior border of heart?
5 LICS parasternally
When does the heart contract?
Day 21
What forms the cardiac veins?
Migration of neural crest cells in embryonic development
What is echocardiogram?
Cardiac ultrasound
What is an electrocardiogram?
Measures impulses
How can heart be catherization?
Femoral artery
What is the transposition of great arteries?
Aorta continues from the RV
Pulmonary trunk continues from LV
Congenital birth defect
- the NCC-derived aortiopulmonary septum that divides the common artery did not form
- “arterial switch” procedure carried out
What is dextrocardia?
Position of the heart is reversed
Apex is on the right, not the left
If dextrocardia occurs with general transposition of organs (situs I versus) = heart functions normally
Isolated dextrocardia = severe defects!
Where is blood oxygenated at placenta per tally?
Umbilical vein => IVC => right atrium
RA -foramen ovale -> LA -> LV -> Aorta (bypasses the. Lungs)
What is the foramen ovale called postnatally?
Fossa ovalis
What is the ductus arteriosus?
Shunts blood from the left pulmonary artery into the arch of aorta
Postnatally = called the ligamentum arteriosum
What muscles does the right atrium have?
Pectinate muscles
- begins at the 3rd costal cartilage
What separates the RV/LV?
IVS
What is the LA?
Forms much of the base off the heart
- 4 pulmonary veins enter
- left auricle is made up of pectinate muscles
What is the LV?
Apex of the heart
Covers the diaphragmatic surface
Carries:
- traberculae carnae
- papillary muscles
Hoarse voice:
Stretching of the left recurrent laryngeal nerve
- loops under the arch of the aorta next to the ligaamentum arteriosum
LRLN - supplies muscles of the larynx
Where do the following structures exit the diaphragm?
Inferior vena cava = T8 Esophagus = T10 Aorta = T12 - aorta bifurcation L4 - inferior vena cava L5
Celiac Trunk Branching
T12
Superior Mesenteric Artery
L1
Inferior Mesenteric Artery
L3
How does the superior part of common hepatic artery branch?
Right gastric Proper hepatic - left hepatic - right hepatic - - cystic
Where does the inferior part of common hepatic Branagh to?
Gastroduodenal artery
- anterior/posterior superior pancreatoduodenal branch
- anastomoses with anterior/posterior inferior pancreatoduodenal
- gastroomenal (gastroploic artery)
Where does the trachea bifurcate?
T4/T5 Manubristernal junction (sternal angle of Louis)
Where is the superior opening of thorax?
T1
1st pair of ribs
Superior border of manubrium
Where is the inferior thoracic apeture?
Bordered by T12
Xiphoid process of T9
Covered by diaphragm
What is the caval opening?
T8 level
Allows the IVC to empty into the RA
During inspiration, the diaphragm contracts and widens the caval opening to allow increased blood flow through the IVS
What is the order of covering of heart?
Pericardium (multilayered sac that covers the heart vessels)
Fibrous Pericardium
- thick connective tissue
- protects against overfilling
- keeps heart in position — attaches to the central tendon
- phrenic nerve
Inner Serous Pericardium (mesothelium of 2 layers)
- parietal
- visceral (epicardium, covers heart, continuous with parietal pericardium)
What is VSD?
Causes left -> right shunting
- leads to pulmonary hypertension
- might cause cardiac failure
Muscular VSDs
Often spontaneously close during birth
Membranous VSDs
Occurs as a result of complex formation -> affects the AV bundle of cardiac conduction system
What are ASDs?
Atrial septal defects
- incomplete closure of the foramen ovale
- clinically significant bc:
Allows shunting of blood from LA -> RA
Leads to overload of the pulmonary vascular system
Leads to Right Ventricular Hypertrophy
What is the ductus arteriosus?
Prenatal structure
- shunts blood from the left pulmonary artery to the arch of the aorta (left side of the heart)
at birth:
Increase in O2, bradykinin, decrease in prostaglandins = smooth muscle contracts and forms the ligamentum arteriosum
What is the sinus venarum?
Openings into the RA
SVC (3rd rib)
IVC
Coronary Sinus (with it cardiac vein supply)
What is the fossa ovalis?
Separates the RA and LA
What is the coronary sinus?
Situated between the IVC opening and the RV opening
What muscles are in the Rough RA?
Pectinate muscles
What smooth muscles are in the RA?
Sinus venarum
What forms the largest part of the anterior surface of the heart?
RV
- muscular traberculae carnae = internal RV
- papillary muscles = finger-like projections internal RV
What is systole?
ventricular contraction
AV valve stops regurgitation = blocks backflow into atrium
- blood outflows via conus arteriosus/infundibulum into pulmonary trunk
What is the conus arteriosus/infundibulum?
Outflow of blood from RV to pulmonary trunk
The pulmonary trunk bifurcated where?
Below the arch of aorta into left and right pulmonary arteries
What does the left pulmonary artery contain?
Ligamentum arteriosum, connects to the arch of the aorta