Heart Flashcards
-Disturbing artery
-consists mainly of smooth muscle circularly arranged
-femoral is an example
-vasoconstricts to regulate blood flow to different body parts
Medium arteries
-conducting arteries
-many elastic layers
-maintains BP between heart contractions for elasticity
Large arteries
-thick muscular wall
-degree of arterial pressure regulated by tonus
-above normal = hypertension
Small arteries & arterioles
-Collateral circulation
-doesn’t include true terminal arteries
-more prevalent in veins
Anastomoses
-forms venous plexus such as dorsal venous arch
Small veins & venules
-in limbs
-where blood flow is opposed by gravity
-has valves
Medium veins
-wide bundles of longitudinal smooth muscle
-well-developed tunica adventitia
Large veins
Leg 🦵 muscles milking blood 🩸 superiorly to the heart 🫀
-defect causes varicose veins (caliber greater than normal, incomplete valves)
Musculovenous pump
Has double helical orientation for wringing contraction
Myocardium
Shunt blood 🩸 from pulmonary artery to aorta
-ligamentum arteriosum is a remnant
Ductus Arterious
-Linoleic acid (18:2 9, 12 Omega6)
-Linolenic acid (18:3 9,12,15 Omega3)
-exists because elongation doesn’t go beyond 9C
-CH3-(CH2)n-COOH
1.C#, 2.Bond#, 3.Position#
Essential fatty acids
Increases surface area of hydrophobic droplets
Emulsification
Produces free cholesterol and FA
Cholesterol esterase
Produces glycerylphospatidylcholine and 2FA
Phospholipase
Removes FA at C1 & C3 of TAGs to produce 2-monoacylglycerol & 2FA
Pancreatic lipase
-Activated by trypsin
-anchors lipase to aqueous-lipid interface
Colipase
-caused by cystic fibrosis, short bowl syndrome, & low pancreatic enzymes
-leads to steatorrhea
Lipid malabsorption
-lipid & bile salt ball
-enters enterocyte
Mixed micelles
-Cholesterol is re-esterified here with FA
-chylomicrons packaged here
Enterocyte
-recognition sites
-activators or coenzymes
-structural components
-freely exchanged
Apoproteins
In liver and kidneys
Glycerol
In muscle
FFA
-Condensation
-reduction
-dehydration
-reduction
FA synthesis key reactions