Health, Disease, Defence Mechanisms and Treatments Flashcards

1
Q

What is health?

A

Health is being free from communicable and non-communicable disease.

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2
Q

What do diseases do to society?

A

The presence of disease has an effect on society, as unhealthy people may not be able to work and require care.

The NHS spends billions of pounds per year treating and looking after sick people.

Most of the NHS budget is spent on medicine and the salaries of doctors and nurses.

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3
Q

What type of disease is HIV, how does it spread and how do you control/prevent/treat it?

A

HIV is a virus.

It spreads by the exchange of bodily fluids during sex and by infected blood.

Using a condom will reduce risk of infection, as will drug addicts not sharing needles.

No cure but is currently controlled by drugs.

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4
Q

What type of disease is cold/flu, how does it spread and how do you control/prevent/treat it?

A

They are viruses.

They are airborne (droplet infection).

There is a flu vaccination for targeted groups.

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5
Q

What type of disease is Human Papilloma Virus (HPV), how is it spread and how it is controlled/prevented/treated?

A

It is a virus.

It is spread by sexual contact.

HPV vaccine is offered to 12-13 year old girls to protect against developing cervical cancer.

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6
Q

What type of virus is Salmonella, how is it spread and how is it controlled/prevented/treated?

A

It is a bacteria.

It is spread from contaminated food.

Always cook food thoroughly and do not mix cooked and uncooked foods, this can control spread.

Treatment by antibiotics.

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7
Q

What type of disease is Tuberculosis, how is it spread and how is it controlled/prevented/treated?

A

It is a bacteria.

It is airborne (droplet infection).

If contracted, treated with drugs including antibiotics.

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8
Q

What type of disease is chlamydia, how is it spread and how is it controlled/prevented/treated?

A

It is a bacteria.

It is spread by sexual contact.

Using a condom will reduce risk of infection.

It is treated by antibiotics.

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9
Q

What type of disease is Athlete’s foot, how is it spread and how is it controlled/prevented/treated?

A

It is a fungus.

It is spread by contact.

To reduce infection risk, avoid direct contact in areas where spores are likely to be present, e.g. wear ‘flip flops’ in changing rooms/ swimming pools.

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10
Q

What type of disease is Potato blight, how is it spread and how is it controlled/prevented/treated?

A

It is a fungus.

Spores spread in the air from plant to plant especially in humid and warm conditions.

Crop rotation and spraying plants with fungicide can prevent it.

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11
Q

What are Aseptic techniques?

A

Aseptic techniques ensure the microorganisms being investigated do not escape or become contaminated with an unwanted microorganism.

The growth of unwanted,
pathogenic microorganisms are also prevented.

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12
Q

What are some Aseptic techniques?

A

No eating or drinking in the lab.

Wiping bench with disinfectant/alcohol.

Not growing microorganisms at body temperature.

Using sterile loops when transferring
cultures.

Flaming culture bottle necks to prevent contamination.

Sterilising (using an autoclave) or disposing of all used equipment.

Washing hands thoroughly.

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13
Q

What are the steps in aseptic techniques to grow uncontaminated
colonies of bacteria in nutrient broth or on an agar
plate?

A

1.Complete the procedure with a Bunsen burner on the bench to kill airborne microorganisms.

2.Pass a metal loop through the flame to sterilise it.

3.Allow the metal loop to cool to prevent any microorganism it touches being killed.

4.Remove the culture bottle lid and sweep the neck of the bottle through the flame to sterilise it.

5.Glide the metal loop through the bacterial culture. This will inoculate the metal loop with bacteria.

6.Sweep the neck of the bottle through the flame to sterilise it again.

7.Replace the culture bottle lid to prevent contamination.

8.Partially lift the Petri dish lid to prevent the entry of unwanted airborne microorganisms.

9.Gently glide the inoculated metal loop over the surface of the nutrient agar (agar enriched with nutrients and minerals essential for bacterial growth). This is known as plating.

10.Pass the metal loop through the flame again to sterilise it.

11.Tape the Petri dish lid on.

12.Incubate at 25°C – below body temperature to ensure pathogenic microorganisms do not grow. Incubate upside down to avoid condensation dripping on the bacteria.

Afterwards, clean work surfaces and hands and safely dispose of bacterial cultures by autoclaving.

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14
Q

What does mucus do?

A

Your air passages have cells that make mucus. This is a sticky slime that traps dust and microbes in the air that we breathe in. Tiny hairs called cilia move to and fro, pushing the mucus up to your throat where it is swallowed.

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15
Q

What does your skin do to protect you?

A

The dead, outer layer of your skin forms a barrier to pathogens.

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16
Q

What happens if you get cut?

A

If you get cut your blood clots and a scab forms. This stops the pathogens from getting in.

17
Q

What do white blood cells (lymphocytes) do in response to antigens?

A

They produce antibodies that cause pathogens to clump together. This will cause a reduced spread of disease and so less symptoms will show.

18
Q

What do phagocytes do?

A

Once the microorganisms are clumped together they are then easily destroyed.

The phagocyte (white blood cell) will first of all engulf the bacterium (surrounds it).

Then it will digest it by releasing enzymes which break it down and destroy it.

19
Q

What is immunity?

A

If you have a high enough antibody level to protect you against a particular infection, you are immune.

20
Q

What is active immunity?

A

This is when the body is activated and produces the antibodies needed to fight an infection.

Active immunity is:

Slow acting;

Provides long-lasting protection.

The primary response when a microorganism enters the body is described as natural active immunity.

Vaccines provide artificial active immunity.

21
Q

What is passive immunity?

A

This is when ready-made antibodies, from another source, are introduced to the body.

Passive immunity is:

Fast acting;

Only lasts a short period of time.

Breastfeeding provides a baby with natural passive immunity.

Anti-venom provides artificial passive immunity after a poisonous bite.

22
Q

What are antibiotics?

A

Antibiotics, are chemicals produced by fungi that are used against bacterial
diseases to kill bacteria or reduce their growth.

23
Q

What has overuse of antibiotics caused?

A

The overuse of antibiotics by people has led to bacteria becoming resistant to them meaning that the antibiotic then becomes ineffective against the bacteria.

E.g. MRSA.

24
Q

What are procedures used to reduce the incidence of ‘superbugs’?

A

Good hygiene - immediate thorough cleaning of spillages of bodily fluids.

Wearing of gloves by hospital staff.

Isolate patients who contract a ‘superbug’.

25
Q

Why are super bugs difficult to eradicate?

A

They are most common in hospitals as:

Patients have a weak immune system.

Some patients have open wounds

Hospitals are antibiotic-rich environments meaning that the non-resistant bacteria are killed off and the resistany ones survive and reproduce.

26
Q

What is a vaccination?

A

A vaccination is the injection of dead or modified microorganisms.

The body’s lymphocytes produce antibodies in response to the antigens present in the vaccine.

Memory lymphocytes will also be produced – this is the primary response.

If this microorganism is encountered after the vaccine, the memory lymphocytes will produce large numbers of the antibody very quickly.

The individual does not get sick – this is the secondary response.

Sometimes a booster vaccination is needed to maintain the high levels of antibodies needed to provide immunity.

27
Q

What are communicable diseases?

A

inherited – some people may carry a gene that
predisposes them to some cancers

• lifestyle,

including:

– poor diet: excess sugar and fat intake;

– lack of exercise: energy used in exercise being
lower than energy intake is the cause of obesity;

– overexposure to the Sun: ultraviolet (UV)

radiation causes mutations leading to skin cancer;

– misuse of drugs:

alcohol: binge drinking can cause liver disease
and affect foetal development (foetal alcohol
syndrome);

tobacco smoke: tar can cause bronchitis
(narrowing of bronchi and bronchioles),
emphysema (damage to alveoli reducing the
surface area for gas exchange) and lung cancer (abnormal cell division);

nicotine is addictive and affects heart rate; and
carbon monoxide combines with red blood cells to reduce the oxygen-carrying capacity of
the blood.

28
Q

What can obesity cause?

A

It can cause cardiovascular diseases and Type 2 diabetes.

29
Q

What are the steps in a heart attack?

A
  1. Cholesterol builds up in a coronary artery
  2. The artery becomes narrower as a blockage/clot forms.
  3. Blood flow is restricted.
  4. The heart muscle is starved of glucose and oxygen.
  5. Respiration is reduced or stopped.
  6. Heart cells die.
30
Q

What is a stroke?

A

A blockage in the blood vessels to the brain causes
death of brain cells, resulting in reduced brain
function (stroke);

31
Q

What is angioplasty and stents?

A

An angiograph allows doctors to see inside a blood vessel.

Dye is added to the blood providing the contrast necessary to view the affected blood vessel.

Balloon-like structures are inserted to hold the blood vessel open and a stent is inserted to keep the blood vessel open.

This is a treatment for cardiovascular disease.

32
Q

What can drugs do to treat cardiovascular disease?

A

Statins reduce blood cholesterol levels. Aspirin ‘thins’ the blood, making it less ‘sticky’.

These drugs reduce the risk of a blockage or clot and therefore a heart attack or stroke.

They are given to individuals at risk of a heart attack or stroke or who have already had one.

33
Q

What lifestyle changes can stop cardiovascular diseases?

A

Reduce fat intake

Stop smoking

Reduce stress

Increase exercise

34
Q

What lifestyle factors can increase risk of cardiovascular diseases?

A

excess dietary fats, smoking, stress and lack of exercise

35
Q

What is cancer?

A

Cancer is uncontrolled cell division that can lead to the development of a tumour.

36
Q

What are the two types of tumour?

A

Benign, malignant.

37
Q

What is a benign tumor?

A

Encapsulated – surrounded by a boundary or capsule.

Do not spread.

Usually not dangerous.

38
Q

What is a malignant tumour?

A

Less likely to have a capsule.

Can spread around the body.

Usually much more dangerous than a benign tumour.

39
Q

What lifestyle choices can reduce chances of developing different types of cancer?

A

HPV vaccine – given to 12-13 year old girls to protect against cervical cancer.

Stop smoking because it can cause lung cancer.

Reduce exposure to UV light because it can cause skin cancer.