Headache Flashcards

1
Q

What are the pain-sensitive structures that can cause headaches?

A

dura, dural venous sinus, falx cerebri, middle meningeal artery, circle of Willis, anterior meningeal artery, scalp, CN-5, 9, 10, and proximal segment of pial arteries.

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2
Q

the pain-insensitive structures that do not cause headaches

A

pial veins, choroid plexus, cerebral parenchyma, and ependyma

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3
Q

difference between primary and secondary headaches?

A

Primary headaches have no organic or structural cause and are often benign and recurrent, while secondary headaches have a structural or organic cause present.

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4
Q

most consistent finding in increased intracranial pressure?

A

papilledema

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5
Q

recommended treatment for acute attacks of tension type headache?

A

Small dose NSAID’s.

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6
Q

recommended long-term treatment for tension type headache?

A

Amitriptyline or TCA.

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7
Q

the different patterns of aura in classical migraine?

A

Visual (more common), auditory, or abdominal aura.

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8
Q

most common pattern of aura in classical migraine?

A

Zig zag pattern on visual field.

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9
Q

other patterns of aura in migraine?

A

Fortification spectra like a rainbow, Scintillating scotomas.

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10
Q

associated symptoms of migraine?

A

photophobia, phonophobia, nausea with or without vomiting.

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11
Q

patient’s preference during a migraine attack? And duration

A

to be in a quiet, dark room. 4-72 hours

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12
Q

most important cytokine linked with migraine headaches?

A

calcitonin gene related peptide.

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13
Q

pathogenesis of migraine headaches according to the vascular theory?

A

Aura is due to vasoconstriction, following which there is a vasodilatation which causes headache.

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14
Q

pathogenesis of migraine headaches according to the serotonin theory?

A

Increased serotonin levels are linked with migraine headaches.

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15
Q

the epicenter of pain in migraine headaches?

A

The epicenter of pain is the trigeminovascular complex.

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16
Q

What is ophthalmoplegic migraine?

A

Ophthalmoplegic migraine is a migraine with transient unilateral 3rd nerve palsy

17
Q

What is basilar type migraine?

A

Basilar type migraine is a migraine with transient posterior circulation symptoms.

18
Q

the treatment for mild attacks, mild to moderate, DOC for moderate to severe of migraine?

A

Paracetamol
NSAIDs (Naproxen - 550mg or Ibuprofen - 400mg).
Triptans

19
Q

mechanism of action of triptans?

A

5HT 1B/1D agonist causing vasoconstriction.

20
Q

intranasal triptan used for treating migraine?

A

Zolmitriptan, sumatriptan.

21
Q

treatment for very severe attacks of migraine?

A

6mg subcutaneous sumatriptan

22
Q

What is given along with triptans to treat vomiting?

A

Dopamine antagonists (Metoclopramide).

23
Q

the issues with triptans?

A

Clinical efficacy depends on T max,
ineffective in migraine with aura,
contraindicated in patients with cardiovascular or cerebrovascular disease.

24
Q

the first-line drug for prophylaxis of migraines?

A

Propranolol or TCA or Topiramate.

25
Q

mechanism of action of Flunarizine?

A

It is a selective sodium channel blocker.

26
Q

contraindication for Ergotamine?

A

Patients with cardiovascular or cerebrovascular disease.

27
Q

monoclonal antibody against CGRP?

A

Erenumab

28
Q

example of Trigeminal Autonomic Cephalgia?

A

Cluster headache

29
Q

drug of choice for patients with cardiovascular or cerebrovascular disease?

A

Dihydro-ergotamine.

30
Q

second-line drug for prophylaxis of migraines?

A

Telmisartan or venlafaxine or valproate.

31
Q

What is the preferred treatment for Hemicrania Continua?

A

Indomethacin

32
Q
A