Head and Neck CA Flashcards

1
Q

Non-healing ulcer/ sore
Loosening of teeth or ill-fitting dentures
Dysphagia/ Odynophagia
Wt loss
Bleeding
Referred otalgia
Neck mass
Are all ssx of what cancer

A

Oral Cavity Cancer

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2
Q

Neck mass
Chronic serous otitis media
Pain
Are all ssx of what cancer

A

Nasopharynx Cancer

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3
Q

Chronic sore throat
Referred otalgia
Late sx - change in voice/ hoarseness, dysphagia, trismus (locked jaw)
Are all ssx of what cancer

A

oropharynx cancer

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4
Q

Patients often remain asymptomatic for a long period
presenting complaints - pain, bleeding, neck mass
are all ssx of what cancer

A

posterior pharyngeal wall cancer

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5
Q

70-80% of pts have clinically involved cervical nodes at the same time of diagnosis - ssx of what cancer

A

hypopharynx cancer

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6
Q

usually dx late stage can present with airway obstruction and neck mass due to lymphadenopathy =

A

supraglottic cancer

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7
Q

often causes sx early:
persistent hoarseness
dysphagia
referred otalgia
chronic cough
hemoptysis
stridor =

A

glottic laryngeal

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8
Q

Over 60% of pts with head and neck cancer present with

A

cervical lymphadenopathy

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9
Q

Head and Neck CA is dx by

A

bx

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10
Q

Refer immediately to ____ if Head/Neck CA suspected

A

EENT

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11
Q

Testing for Head/Neck CA can include:

A

Panendoscopy (laryngoscopy, Bronchoscopy, Esophagoscopy)
CT or MRI
PET scan
CBC, LFTs, CMP

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12
Q

Neck Mass DDX

A

congenital - Branchial cleft cyst, thyroglossal duct cyst, vascular abnormalities
Infectious/ inflammatory
Malignant

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13
Q

Branchial Cleft Cysts are

A

by the 5th week of pregnancy these “gills” should go away but when they don’t they form this
located right below the ear or anterior to the sternocleidomastoid muscle

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14
Q

Thyroglossal duct cyst is located

A

superior of cricoid cartilage, inferior of hyoid bone

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15
Q

if infection is unlikely, mass doesn’t resolve, or mass recurs ___________ is required

A

further workup

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16
Q

first imaging study =

A

CT

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17
Q

staging for head/neck cancer

A

TNM staging
Tumor
nodes
mets

18
Q

Early stage treatment (stage 1 & 2)
small localized disease without nodal involvement

A

treat with either surgery or radiation

19
Q

Locally advanced (high risk for local recurrence)

A

chemo is gold standard
surgery reserved to preserve organ function

20
Q

Early stage head and neck CA prognosis

A

70-90% survival

21
Q

Late stage head and neck CA prognosis

A

30-60% survival

22
Q

Late stage head and neck CA prognosis

A

30-60% survival

23
Q

Cancers due to HPV appear to have a better

A

prognosis

24
Q

Head and Neck CA prevention vaccines

A

HPV (Gardisil, Gardisil 9, Cervarix)

25
Q

Leukoplakia =

A

Premalignant lesion
white patch on oral mucosa that cannot be scraped off
bx is needed - 20% develop into invasive cancer in

26
Q

Leukoplakia =

A

Premalignant lesion
white patch on oral mucosa that cannot be scraped off
bx - precancerous
20% develop into invasive cancer in 10 years

27
Q

Erythroplakia =

A

red patch on the oral mucosa
dx - precancerous
more likely than leukoplakia to become malignant or have an invasive component (30-50%)

28
Q

Hairy Leukoplakia =

A

EBV induced lesion
always HIV infected or immunocompromised pts
NOT a premalignant lesion
painless white patch - often tx is not needed

29
Q

Nasal/ Paranasal CA is _____ and is more common in _____

A

rare
men ~ 60-65 yo

30
Q

Most common site of Nasal/ Paranasal CA

A

maxillary sinus
second - ethmoid sinus

31
Q

Nasal/ Paranasal CA ssx

A

pain
nasal obstruction
epistaxis
chronic sinus congestion
hyposmia/ microsmia*

32
Q

Nasal/ Paranasal CA dx you need a

A

bx
workup - CT, endoscopy, MRI

33
Q

Nasal/ Paranasal CA dx you need a

A

bx
workup includes - CT, endoscopy, MRI

34
Q

Nasal/ Paranasal CA are usually related to

A

occupational exposures

35
Q

Nasal/ Paranasal CA staging

A

TNM staging
most do NOT have lymph node involvement

36
Q

most Nasal/ Paranasal CA do NOT have ________

A

lymph node involvement

37
Q

80+% of Nasal/ Paranasal CA have ______ invasion

A

bony

38
Q

Nasal/ Paranasal CA treatment

A

surgery and radiation

39
Q

Salivary gland tumors are most common in

A

80-85% = parotid gland, 80% = benign
tumors in other salivary glands more likely to be malignant

40
Q

Nasal/ Paranasal CA prognosis

A

overall poor
T1 = 50% and the further you go the further it drops