Head and Neck Flashcards
Nasopharyngeal angiofibroma
a) Occurs primarily in adolescent males
b) Is androgen receptor positive
c) Is a malignancy that frequently metastasizes
d) A & B e) All of the above
D
Sinonasal undifferentiated carcinoma
a) Is an aggressive malignancy
b) Usually stains for cytokeratin
c) Is usually negative for chromogranin
d) A & B
e) All of the above
E
Intestinal type adenocarcinoma of the sinuses
a) Usually stains for CDX2, CK7, and CK20
b) Is considered to be a low-grade tumor with a good prognosis
c) Can be easily differentiated from metastatic colon cancer by its staining profile
d) A & B
e) All of the above
A
Odontogenic keratocyst a) Can be associated with nevoid basal cell carcinoma syndrome b) Can occur in the mandible or maxilla c) Rarely undergoes malignant degeneration d) A & B e) All of the above
E
Salivary duct carcinoma a) Is a low-grade salivary gland tumor b) Usually does not metastasize or recur locally c) Often stains for androgen receptor and HER2/neu d) A & B e) All of the above
C
Olfactory neuroblastoma a) Usually stains for chromogranin and synaptophysin b) Rarely stains for cytokeratin c) May stain for S100 in a sustentacular cell pattern d) A and B e) All of the above
E
Schneiderian papillomas a) Are classified as inverted, exophytic (or fungiform), and oncocytic types. b) Do not have metastatic potential, but can have malignant degeneration. c) Are tumors of minor salivary gland origin d) A and B e) All of the above
D
Neuroendocrine carcinoma in the sinonasal tract a) Is associated with EBV b) Is more common in Southeast Asia c) Stains for neuroendocrine markers d) A and B e) All of the above
C
Necrotizing sialometaplasia a) May be associated with trauma or radiation b) Can be confused histologically with squamous cell carcinoma c) Is not lobular in configuration d) A and B e) All of the above
D
PTC could have: A. Have a RET/PTC translocation B. Be associated with a history of radiation C. Metastasize to the neck lymph nodes. D. A and B E. All of the above
E
Thyroid carcinomas associated with familial syndromes include A. Medullary carcinoma B. Hyalinizing trabecular Tumor C. Anaplastic carcinoma D. A and B E. All of the above
A
Parathyroid carcinomas are best diagnosed A. Using only mitotic count and atypia B. Using only clinical features C. Using a ki-67 stain D. Using gross, histologic and clinical features together E. None of the above
D
Syndromes that may involve the parathyroid glands include A. MEN syndromes B. Hyperparathyroidism jaw tumor syndrome C. VHL syndrome D. A and B E. All of the above
D
