Head and Face Pain Foundations of FN Flashcards
What is necessary for neuronal survival?
- Fuel
2. Activation
What is the fuel for neurons?
Oxygen and Glucose
What is the activation necessary for neuronal survival?
Action potentials resulting in activation of Ciegr
What other factors are needed for neuronal survival?
- Cellular Metabolism
- Vitamins and Minerals
- Antioxidants
- Detoxification
- Neurotransmitters and Substrates
- Lack of Dysbiosis
What are the seven longitudinal levels of a lesion?
- Receptor Organ
- Peripheral Nerve
- Spinal Cord
- Cerebellum
- Brainstem
- Subcortical
- Cortex
What is associated with a high Frequency of Firing?
Healthy individual neurons, neuraxis, and diffuse networks they create
Define Diaschasis
When one part of the nervous system’s influence on another are similar in function but separated anatomically.
What is the Cellular Immediate Early Gene Response (CIEGR) pathway?
- R/C Organ activation
- NMDA R/C
- Ca influx
- Cellular kinase
- Genetic Activation
- C-JUN, C-FOS, C-MYR
- Genetic Response
What is associated with Transferal Degeneration? (TND)
- Decreased CIEGR
- Failure of Na/K Pumps
- Increased Intracellular protein
- Cellular swelling (H2O influx)
- Nuclear displacement due to cytoarchitectural degradation
- Increased free radical damage
- Lysis
What is the Central Integrated State (CIS)?
Sum total of all synaptic activity on a neuron in its resting state of activity.
What determines the CIS?
- Excitatory and Inhibitory inputs
- Temporal and Spatial summation
- Convergence of multiple inputs
What is metabolic capacity?
The clinical application that we make in our assessments based on the concepts of the CIS.
