HCAP/HAP

Question 1

Empiric therapy: No risk for MDRs or early onset pneumonia; name AND dose

Answer 1

unasyn 3g Q6h

ceftriaxone 1-2g Q24h

levofloxacin 750mg Q24h OR moxifloxacin 400mg Q24h

ertapenam 1g Q24h

Question 2

Empiric therapy: WITH risk factors for MDRs or late onset pneumonia; name AND dose

Answer 2

linezolid 600mg q12h OR vancomycin 15mg/kg q12h

PLUS

pip/tazo (anti-pseudomonal BL)

PLUS

levofloxacin (FQ)

Question 3

Rule of thumb for selecting anti-pseudomonal agents for HCAP/HAP patients in regards to empiric vs. definitive therapy?

Answer 3

Empiric=2 anti-pseudomonal agents

Definitive=1 anti-pseudomonal agent

Question 4

Once empiric therapy is initiated, when do you re-assess condition?

Answer 4

Day 2-3 of therapy

Question 5

How long does it take for COMPLETE resolution of lung infiltrates?

Answer 5

6 weeks

Question 6

On what day do you discontinue therapy for MOST pathogens?

Answer 6

Day 8

Question 7

If you have pseudomonas or actineobacter, how long would you treat these infections in HCAP/HAP?

Answer 7

14-15 days