Hardy-Weinberg (Lecture 1-4) Flashcards
What is blending inheritance? (Concept of Heredity before Mendel)
The idea that offspring’s traits are a blend of parental traits
What is the inheritance of acquired characteristics? (Concept of Heredity before Mendel)
Parents develop traits over a lifetime, offspring inherit these novel traits
Define Heredity
The transmission of traits from parents to their traits
Trait
Any characteristic of an indivdiual
What is Genetics
Branch of biology that focuses on inheritance of traits
Why did Gregory Mendel choose peas as his model organism
- Controlled crosses were easy
- Short generation times
- Cheap
- Could produce a lot of seeds
What is the principle of segregation?
Diploid individuals have 2 alleles of each gene and these alleles separate into gametes at meiosis
Is the “Principle of Segregation” due to random chance, or it’s orchestrated/planned
A) Random Chance
B) Orchestrated/Planned
A; Offspring receive an allele of a trait from the parent generation due to random chance
How many gametes does a parent generation contribute to each offspring?
A) 1
B) 2
C) 4
D) 6
A; 1
Are the traits that are inherited from the parent generation…discrete or does blending occur
A) Discrete
B) Blending
A; Discrete
What is the definition of “pure line” species?
Species that have homozygous genotypes
What is the maximum numbers of alleles that a parent carries for a given trait…
A) 1
B) 2
C) 4
D) 8
2; Think of alleles of G or g
What was the point of Mendel’s Dihybrid Cross experiment?
To test the hypothesis that traits are inherited independent of one another
What is the expected/“magic” ratio number resulting from an independent assortment of traits
9:3:3:1
9: Expected offspring with both dominant traits
3 & 3: Expected offspring with combination of dominant and recessive traits
1: Expected offspring with recessive traits
What is “Independent Assortment”
Alleles of different genes (traits) separate independently during the formation of gametes (if on different chromosomes)
How many traits does “Independent Assortment” deal with?
2 or more traits (think of Mendel’s Dihybrid Cross experiment)
What are the different implications of Independent Assortment
- Allows for different combinations of traits to occur in offspring
- Allows for genetic variation in population –> Evolution
What is the formula for the chi-square test
(Observed - Expected)^2/Expected
Do you accept or reject the null hypothesis if your calculated chi-square is higher than the chi-square critical value…
A) Accept
B) Reject
B; Reject the null hypothesis. Meaning one trait most likely does affect the other trait
What is the meaning of the “null hypothesis” in the chi square test?
There is no significant difference between observed and expected frequencies (i.e. genes are unlinked). Meaning one trait doesn’t affect the outcome of the other
What is the meaning of the “alternative hypothesis” in the chi square test?
There is a significant difference between observed and expected frequencies (i.e., genes are linked). Meaning one trait most likely affects the outcome of another