Hard to remember NDEB content Flashcards by Laura Purvis

Melkersson-Rosenthal Syndrome

fissured tongue + granulomatous cheilitis + facial paralysis (Mels Bells, Rosy Red)

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Sturge Weber syndrome

angiomas of leptomenginges + skin along distribution of trigeminal nerve

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Peutz-Jeghers Syndrome

freckles + intestinal polyps + melanotic macules

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Ramsay Hunt Syndrome

herpes zoster reactivation affecting cranial nerves VII and VIII (facial paralysis, vertigo, deafness)

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Sutton disease

major aphthous ulcer

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Stevens Johnson Syndrome

Erythema multiforme major

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Plummer-Vinson Syndrome

Mucosal atrophy + dysphagia + iron deficiency anaemia + increased oral cancer risk (SCC)

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Multiple Endocrine Neoplasia

multiple neuromas + medullary thyroid cancer + pheochromocytoma of adrenal gland

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Neurofibromatosis type I/Von recklinghausen’s disease

multiple neurofibromas (schwann cells and fibroblasts) + café au lait spots + axillary and iris freckles- neurofibromas can transform to neurofibrosarcomas

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McCune-Albright Syndrome

fibrous dysplasia + cutaneous cafe au lait spots + endocrine abnormalities

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2 syndromes associated with sarcoidosis

-Lofgren’s syndrome: erythema nodosum + bilateral hilar lymphadenopathy + arthritis
-Heerfordt Syndrome/uveoparotid fever: anterior uveitis + parotid gland enlargement + facial nerve palsy + fever

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Warthin’s tumour

composed of oncocytes + lymphoid cells (found in parotid of older men)

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Cells associated with Hodgkin’s vs Non-Hodgekins Lymphoma

Hodgkin’s Lymphoma: malignant B cells (Reed-Sternberg cells)

Non-Hodgkin/s Lymphoma: B or T cells

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Burkitt’s Lymphoma

Type of B cell Non-Hodgkin’s Lymphoma with bone marrow involvement
-Swelling, pain, tooth mobility
-Lip paraesthesia
-Halted root development
-Associated with oral hairy leukoplakia (EBV)

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Gardner Syndrome

multiple odontomas + intestinal polyps

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Leukaemia type most common in young > old

(young) AL > CM > AM >CL (old)

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Hereditary Hemorrhagic Telengiectasia (HHT)

-AKA: Olser-Weber-Rendu Syndrome
Iron deficiency anemia + epistaxis,+ abnormal capillary formation of skin, mucosa, viscera + can be blanched

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Osteopetrosis/Albergs-Schonberg disease/Marble bone disease

Lack of bone remodelling and resorption leads to “stone bone”

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Calcifying Epithelial Odontogenic Tumour/Pindborg Tumour

Radiolucency w/ driven snow calcifications, leisegang rings

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Adenomatoid odontogenic tumour

Radiolucency in anterior maxilla and over impacted canines

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Odontogenic myxoma

slimy stroma, messy radiolucency, honeycomb pattern

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2 types of odontogenic fibroma

Central: bone, well-defined multilocular
Peripheral: gum and won’t show radiographically

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Ameloblastic fibroma

Younger patients, posterior mandible, myxomatous connective tissue

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Central ossifying fibroma

Juvenile = aggressive varient.
Heterogenous radiopacity/lucency

Osteoblastoma

circumscribed opaque mass of bone and osteoblasts

Ewing’s Sarcoma

sarcoma of long bones involving “round cells”, rarely affects jaws, affects children, swelling

Metastatic carcimoma

Pain swelling and paraesthesis, ill defined bony changes, breast cancer most common

Granular cell tumour

Neoplasm of schwann cells, pseudoepitheliomatous hyperplasia (PEH) mimics SCC, dorsal of tongue

Giant cell lesions (6)

- **Central Giant Cell Granuloma:** - **Aneurysmal bone cyst:** - **Hyperparathyroidism/Von Recklinghausen’s disease of bone** - **Cherubism**: - **Langerhans Cell Disease/Idiopathic histiocytosis:** - **Paget’s Disease**

Central Giant Cell Granuloma

composed of fibroblasts + giant cells, anterior mandible (central and peripheral)

Aneurysmal bone cyst

blood filled pseudocyst, multilocular radiolucency, posterior mandible, expansile, excision

Hyperparathyroidism

Von Recklinghausen’s disease of bone -Multiple bone lesions, brown tumour (excess osteoclast activity), elevated alkaline phosphatase

Cherubism

symmetrical, expansile bilateral swelling, multilocular, stops growing after puberty

Langerhans Cell Disease/Idiopathic histiocytosis

cancer, “ice cream scoop” radiolucencies, floating teeth

Paget’s Disease

Progressive metabolic disease of bone causing symmetrical enlargement -adults over 50 -elevated alkaline phosphatase due to bone breakdown -“cotton wool” appearance -dentures/hats become tight -treated with bisphosphonates and calcitonin

Multiple Myeloma

-Neoplasm of antibody secreting B cells (plasma cells) -Punched out radiolucencies -Amyloidosis

Van der woude syndrome

Lip pits + clefts

Gorlin syndrome

AKA Nevoid basal cell carcinoma - Multiple OKCs, BCC's

Fibrous Dysplasia

- Ground glass appearance - Stops growing after puberty - Tx: surgical recontour for aesthetics

What are the histologic zones of the pulp?

Predentine Odontoblastic layer Cell-free zone of Weil Cell-rich zone Pulp core

Where is the danger zone for strip perforation in endo?

Distal surface of mesial root of md molars due to concavity of root at the furcation

What is Class I-VI Ellis Classification for trauma?

I: enamel only II: enamel and dentine III: enamel, dentine, pulp IV: traumatised tooth that has become non-vital V: luxation VI: avulsion

MTA- action, minerals, setting time, characteristics

-Stimulates cementoblasts -Calcium, silicon, aluminium -3 hour setting time -Sets in presence of moisture -Antimicrobial -Non-resorbable

T. Denticola

-ANUG/ANUP -Motile, gram-negative spirochete -Penetrates epithelium and connective tissue -Red complex

C. Rectus

-Motile, gram-negative rod -Orange complex

Which bacteria are non-motile, gram negative rods?

F. Nucleatum P. Intermedia T. Forsythia P.gingivalis A. Actinomycetemcomitans

Where are Actinomyces found?

Healthy gingiva, root caries

Bacteria in infected root canal vs reinfected root canal

Infected: Streptococcus viridens Reinfected: E. faecalis

Which condition is often associated with HHT (hereditary hemorrhagic telangiectasia)

Iron deficiency anemia - Epistaxis (nosebleed) common too

How to manage moderate OAC (2-6mm)

4A's and Figure 8 suture Antibiotic Antihistamine Analgesic Afrin (vasoconstrictor decongestant spray)

Blood supply to the TMJ (4)

MADS Maxillary Ascending pharyngeal Deep auricular Superficial temporal

Epstein Pearls vs Bohn's nodules

What is a brown tumour

Benign mass - associated with hyperparathyroidism or end stage renal disease / kidney transplant

How to differentiate between haemangioma and haematoma

Hemangioma blanches upon diascopy Hematoma does not blanch

Red complex bacteria

T Forsythia P Gingivalis T Denticola

Orange complex bacteria

P intermedia Fusobacterium Nucleatum C Rectus

Most common oral bacterium, non-pathogenic

S Salivarius

Bac responsible for root caries

Actinomyces

What is the "bridging" bacterium that supports/links early and later colonizer bacteria in plaque

Fusobacterium Nucleatum