Hand Calc Flashcards
How does MU change when TMR change
as TMR decreases, MU increases
How does TMR change when calc point depth changes
as depth increases, TMR decreases
Whole brain irradiation- patient selection
metastatic diseases: frequent breast, lungs, melanoma, sarcoma, CNS
Goal of treatment (whole brain)
palliation of symptoms
quality of life
prolonging survival
could be prophylactically (PCI)
what us treating prophylactically
PCI given to small cell lung cancer a head of time because patients have brain cancer frequently. when treating prophylactically, we treat the areas that we think will develop cancer later on, so we treat in advance with lower dose (24 Gy in 12 fx)
whole brain immobilization
supine, exact bar, reg.h. “B”, pad on table, mask, arms across chest holding A-bar, knee wedge
where is the isocenter placed for whole brain
mid- separation
why is isocenter placed at mid separation
for homogeneous dose distribution, if the isocenter is off, we will have a hot and cold plan
Conventional Whole brain sim
- Fluoroscopic x-ray will be taken of treatment field
- Doctor draw field (wax pencil in scan or digitally)
- Blocking created (cerrobend or MLC)
Virtual whole brain sim (more realistic)
- Pt receives CT scan
- Axial slices imported into treatment planning computer
- Dr draws field on TPS
- MLCs for blocking
Whole Brain Fields gantry angles
Opposed laterals
tilted anterior
why do we set beam angles tilted anterior and opposed laterals (obliged) for whole brain
TO LIMIT DIVERGENCES TO THE LENSES
How to change gantry angles to limit divergence for whole brain
ex: if beam 1 is at 278 (270+8), beam 2 will be at 82 (90-8)
where is interior border usually placed for whole brain
below C1, or could be below C2 as well but rare
why is the interior border always placed at C1 or C2
patients are usually here for metastatic cancer, chances are they will come back for more treatment. When that happens, we want to know where we stopped at the previous irradiation so that we can avoid overlapping and overtreating that area
Superior and lateral borders incorporate flash for whole brain, why?
patient’s set up can be different each day. flash ensures we have the whole skull covered every treatment. Also, if the field borders are against the head, we do not have adequate dmax to tissue
critical structures to consider when treating whole brain
face
lenses
what happens if we dont consider face and lenses for whole brain irradiation
radiation induced cataract that can develop in 20 years
block position for whole brain
“one thumb length” away from target
Whole brain palliative prescription
30 Gy for 10 fx
Whole Brain PCI fractionation
24 Gy in 12 fx
whole brain calculation
heterogeneous calculation if imported into TPS
what is the normalization of whole brain
100% to iso, no further optimization needed
what happens when you normalize down
plan gets hotter