Hamilton Lectures Flashcards
Metabolism
The whole range of biochemical processes that occur within a living organism.
- Consists of anabolism (the build up of substances) and catabolism (the breakdown of substances
Catabolism
Generate chemical energy by degradation/oxidation of fuel molecules
Anabolism
Biosynthetic, use chemical energy and reducing power NADH, to combine precursors to form complex molecules
Oxidation
Transfer of one or more electrons from one reactant to another
NAD
Nicotinamide adenine dinucleotide
Degradation/oxidation of fuel molecules to generate free energy: 3 stages
I: Digestion and hydrolysis - Breaking down of complex molecules
II: Conversion – Breaking down to 2-, 3-carbon compounds and acetyl CoA
III: Oxidation – Oxidation of acetyl CoA via citric acid cycle and electron flow to O2 via NADH
What stage of generating free energy produces lots of ATP
Stage III
The fate of nutrients
Oxidation
Storage
Conversion
Where is glucose stored? Stored as what?
Liver/muscles - as glycogen
Lactose
Galactose + glucose
Sucrose
Fructose + glucose
Blood glucose: controlled by two hormones
Insulin and glucagon
- Too high: insulin secreted into blood from the pancreas
- Too low: glucagon released: Glycogen converted to glucose
Diabetes Type 1
Deficiency of insulin
Citric acid cycle: location
Mitochondrial Matrix