Hallmarks of cancer Flashcards
1
Q
What are the 6 hallmarks of cancer
A
Sustaining proliferative signalling
evaiding growth suppressors
activatings invasion and metastsis
enabling replacative immortality
inducing angiogenesis
resisting cell death
2
Q
what are the two emerging hall marks
A
avoiding immune destruction
deregulating cellular energetics
3
Q
two enabling hall marks
A
Tumour promoting inflammation
genome instability and mutation
4
Q
Major functional changes in cancer
A
Increased growth
failure to undergo cell death
loss of differentiation
failure to repair DNA damage