Hallmarks of cancer Flashcards

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1
Q

What are the 6 hallmarks of cancer

A

Sustaining proliferative signalling
evaiding growth suppressors
activatings invasion and metastsis
enabling replacative immortality
inducing angiogenesis
resisting cell death

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2
Q

what are the two emerging hall marks

A

avoiding immune destruction
deregulating cellular energetics

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3
Q

two enabling hall marks

A

Tumour promoting inflammation
genome instability and mutation

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4
Q

Major functional changes in cancer

A

Increased growth
failure to undergo cell death
loss of differentiation
failure to repair DNA damage

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