hallicinagens, other Flashcards
which two opioids are most abused among health professionals?
meperidine and fentanyl
withdrawal from what addictive drug includes: dysphoria, lacrimation, rhinorrhea, and yawning? is it life-threatening?
opiods - no
how do you treat opioid addiction?
illicit agent replaced by long-acting opiod and dose is slowly reduced
- use methadone or buprenorphine
withdrawal from what type of drugs is caused by a noradrenergic storm? name two drugs used to treat and their MOA
Opioids - heroin
Clonidine and lofexidine - alpha2 agonists
What drug can be used in opioid detox in patients highly motivated to remain opioid free? why only in motivated patients?
Naltrexone - wont satisfy cravings or relieve withdrawal
What drug binds to receptors CB1 and CB2? what type of receptors are these? where is each located?
cannabinoid receptors G protein linked coupled to
GiCB1: brain - major one for psych effects
CB2: immune cells
what is dronabinol? name 2 conditions it helps treat
therapeutic THC (cannabinoid) anorexia in AIDS pts and nausea/vomiting in chemo patients (2nd line)
what three drugs are in the LSD-like group?
LSD
Mescaline
Psilocybin
describe the symptoms of LSD addiction and withdrawal
trick! no addiction or withdrawal!
what drug can be given for a “bad trip” on LSD?
diazepam - helps agitation
ketamine is an analog of what street drug?
phencyclidine aka PCP aka angel dust
what addictive drug causes feelings of empathy and intimacy? how does it work?
MDMA - ecstasycauses release of biogenic amines - mostly serotonin
withdrawal of what drug is characterized by depression lasting several weeks?
MDMA - ecstasy
which addictive drug produces euphoria, analgesia, then loss of consciousness?
nitrous oxide
what two inhalants an be used to enhance erection and are NOT addictive?
amyl nitrite and butyl nitrite
