Hair Flashcards

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1
Q

Name the three types of hair and describe them.

A
  1. Lanugo- fine hairs shed late in gestation and in first months of life
  2. Vellus- fine hairs over face, trunk, and extremities
  3. Terminal- coarse, darker hairs of scalp, eyebrows, and eyelashes; postpubertal androgens switch to terminal hairs at other sites
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2
Q

How many hairs on scalp?

A

100,000 (more in blonde and fewer in red-hair)

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3
Q

Name follicular layers from outer to inner.

A
  • glassy membrane –> outer root sheath –> inner root sheath (Henle hugs Huxley, cutely=cuticle) –> hair shaft (cuticle. cortex)–> medulla
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4
Q

Function of cuticle of hair?

A
  • helps to keep hair intact
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5
Q

damage of cuticle of hair leads to____

A
  • split ends (trichoptilosis)
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6
Q

Describe the hair cycle.

A
  • Anagen is growth phase (Anogen Adds hair)
  • Catagen is regression phase (cat eating the hair)
  • Telogen (club hairs) is the resting phase
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7
Q

How long does each phase of hair cycle last?

A
  • Anagen lasts 2-6 years
  • Catagen lasts 2-3 weeks
  • Telogen lasts 3 months
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8
Q

What percentage of hairs are in each phase of growth cycle at any given moment?

A
  • Anagen= 85-90% (anagen-eighty five)
  • Catagen= 1-2%
  • Telogen= 10-15% (telogen-ten)
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9
Q

phase of active shedding of club hair between telogen and anagen is called _____

A
  • Exogen
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10
Q

how many hairs do we lose in one day?

A

100

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11
Q

How fast does hair grow/day/month?

A

0.4mm/day, 1cm/month

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12
Q

What happens to melanocytes in hair matrix during Catagen phase?

A
  • they apoptose
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13
Q

What phase of hair cycle do melanocytes produce pigment?

A
  • only in Anagen (anagen–>adding pigment)
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14
Q

Hair follicle melanin unit is ____# of melanocytes and ____ keratinocytes

A

1 melanocyte: 5 keratinocytes

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15
Q

hair follicle stem resides in the ____ and contributes to tissue regeneration and hair cycling

A
  • bulge
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16
Q

What determines the curliness of hair?

A
  • disulfide bonds via cysteine residues