HAI & antibiotics Flashcards

1
Q
  1. What percentage of hospital patients experience hospital-acquired infections (HAI) according to the CDC?
    • A) 1 in 15
    • B) 1 in 20
    • C) 1 in 31
    • D) 1 in 50
A

Answer: C) 1 in 31

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2
Q
  1. Which of the following is NOT a common source of HAI?
    • A) Central line-associated sepsis
    • B) Ventilator-associated pneumonia
    • C) Appendectomy
    • D) Clostridium difficile infections
A

Answer: C) Appendectomy

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3
Q
  1. Which of the following are common risk factors for hospital-acquired infections? select 2
    • A) Older age
    • B) Mechanical ventilatory support
    • C) Short hospital stay
    • D) Strong immune system
      Answer: A) Older age, B) Mechanical ventilatory support
A

Answer: A) Older age, B) Mechanical ventilatory support

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4
Q
  1. Which of the following are types of surgical site infections (SSI)?
    • A) Superficial incisional
    • B) Organ or space
    • C) Deep incisional
    • D) Systemic incisional
A

Answer: A) Superficial incisional, B) Organ or space, C) Deep incisional

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5
Q
  1. What is the most common surgical site infection (SSI)?
    • A) Superficial incisional
    • B) Deep incisional
    • C) Organ or space
    • D) All of the above
A

Answer: A) Superficial incisional

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6
Q
  1. Which pathogen is most commonly associated with hospital-acquired infections?
    • A) Staphylococcus
    • B) Streptococcus
    • C) Pseudomonas
    • D) E. coli
A

Answer: A) Staphylococcus

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7
Q
  1. Which of the following is a risk factor for surgical site infection (SSI)?
    • A) Diabetes
    • B) Short hospital stay
    • C) Clean surgical wound
    • D) Adequate glycemic control
A

Answer: A) Diabetes

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8
Q
  1. Which type of surgical wound involves spillage of contents from an internal organ?
    • A) Clean
    • B) Clean-contaminated
    • C) Contaminated
    • D) Dirty
A

Answer: C) Contaminated

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9
Q
  1. What percentage of surgical site infections (SSIs) are potentially preventable?
    • A) 10%
    • B) 25%
    • C) 50%
    • D) 75%
      Answer: C) 50%
A

Answer: C) 50%

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10
Q
  1. Which of the following is NOT a recommendation for antibiotic prophylaxis during surgery?
    • A) Administer antibiotics within 1 hour of incision
    • B) Use the newest antibiotics available
    • C) Ensure adequate bactericidal concentration in tissues
    • D) Re-dose antibiotics for prolonged procedures
A

Answer: B) Use the newest antibiotics available

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11
Q
  1. What is the main goal of preoperative prophylaxis?
    • A) Prevent surgical errors
    • B) Ensure complete sterilization of the operating room
    • C) Achieve adequate bactericidal concentration in serum and tissues during surgery
    • D) Reduce patient anxiety
A

Answer: C) Achieve adequate bactericidal concentration in serum and tissues during surgery

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12
Q
  1. Which of the following antibiotics is typically administered before surgery to prevent infection?
    • A) Penicillin
    • B) Cefazolin
    • C) Metronidazole
    • D) Ciprofloxacin
A

Answer: B) Cefazolin

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13
Q
  1. What is the common adverse reaction to vancomycin administration?
    • A) Rash
    • B) Nephrotoxicity
    • C) Diarrhea
    • D) All of the above
A

Answer: D) All of the above

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14
Q
  1. Which of the following pathogens is most likely to cause bloodstream infections and endocarditis in hospital settings?
    • A) Pseudomonas
    • B) E. coli
    • C) MRSA
    • D) Streptococcus
A

Answer: C) MRSA

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15
Q
  1. Which antibiotic class inhibits bacterial cell wall synthesis?
    • A) Beta-lactams
    • B) Aminoglycosides
    • C) Fluoroquinolones
    • D) Metronidazole
A

Answer: A) Beta-lactams

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16
Q
  1. Which generation of cephalosporins has the best penetration of the blood-brain barrier?
    • A) 1st
    • B) 2nd
    • C) 3rd
    • D) 4th
A

Answer: D) 4th

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17
Q
  1. What is the main adverse reaction associated with fluoroquinolones?
    • A) Cartilage damage/tendon rupture
    • B) Nephrotoxicity
    • C) Ototoxicity
    • D) Hypersensitivity
A

Answer: A) Cartilage damage/tendon rupture

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18
Q
  1. What is the mechanism of action for metronidazole?
    • A) Inhibits DNA protein synthesis
    • B) Inhibits cell wall synthesis
    • C) Forms toxic byproducts that damage DNA
    • D) Inhibits ribosomal protein synthesis
A

Answer: C) Forms toxic byproducts that damage DNA

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19
Q
  1. Which of the following antibiotics should be avoided in patients with a known allergy to penicillin?
    • A) Cefazolin
    • B) Metronidazole
    • C) Amoxicillin
    • D) Ciprofloxacin
A

Answer: C) Amoxicillin

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20
Q
  1. Which of the following describes deep incisional surgical site infections?
    • A) Occurs only on the surface of the skin
    • B) Occurs beneath the incision area in muscles and surrounding tissues
    • C) Occurs only in organs or spaces between organs
    • D) Occurs as a result of superficial wounds
A

Answer: B) Occurs beneath the incision area in muscles and surrounding tissues

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21
Q
  1. Which organism is commonly found in ventilator-associated pneumonia? mulitple choice
    • A) Staphylococcus aureus
    • B) Pseudomonas aeruginosa
    • C) Streptococcus pneumoniae
    • D) Clostridium difficile
A

Answer: B) Pseudomonas aeruginosa (gram negative)
- A) Staphylococcus aureus (gram positive).

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22
Q
  1. Which of the following is a major risk factor for urinary catheter-associated UTIs?
    • A) Short hospital stay
    • B) Older age
    • C) Use of central venous lines
    • D) Immunosuppression
A

Answer: B) Older age

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23
Q
  1. What is the main cause of Clostridium difficile infections in hospital settings?
    • A) Improper hand hygiene
    • B) Contaminated water
    • C) Overuse of antibiotics
    • D) Blood transfusions
      *
A

*Answer:** C) Overuse of antibiotics

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24
Q
  1. Which of the following is the appropriate timing for administering surgical prophylactic antibiotics?
    • A) After surgery begins
    • B) Within 1 hour of incision
    • C) After surgery has ended
    • D) At the time of hospital admission
A

Answer: B) Within 1 hour of incision

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25
Q
  1. Which type of wound involves evidence of infection at the time of surgery?
    • A) Clean wound
    • B) Contaminated wound
    • C) Dirty wound
    • D) Clean-contaminated wound
A

Answer: C) Dirty wound

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26
Q
  1. Which infection control practice is essential to preventing hospital-acquired infections (HAI)?
    • A) Use of gloves alone
    • B) Hand hygiene
    • C) Sterile surgical gowns only
    • D) Isolation of patients
A

Answer: B) Hand hygiene

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27
Q
  1. Which of the following is NOT a part of the patient history that indicates possible infection?
    • A) Night sweats
    • B) Productive cough
    • C) Increased appetite
    • D) Dysuria
A

Answer: C) Increased appetite

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28
Q
  1. Which surgical antibiotic is commonly re-dosed for prolonged procedures?
    • A) Ciprofloxacin
    • B) Cefazolin
    • C) Metronidazole
    • D) Vancomycin
A

Answer: B) Cefazolin

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29
Q
  1. Which symptom is NOT commonly associated with surgical site infections (SSI)?
    • A) Redness
    • B) Fever
    • C) Delayed healing
    • D) Increased energy levels
A

Answer: D) Increased energy levels

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30
Q
  1. Which surgical procedure is more prone to hospital-acquired infections (HAI)?
    • A) Emergency surgery
    • B) Clean surgery
    • C) Appendectomy
    • D) Dental surgery
A

Answer: A) Emergency surgery

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31
Q
  1. What is the role of glycemic control in the prevention of surgical site infections?
    • A) Maintaining blood sugar levels below 100

mg/dL
- B) Preventing infections with glucose levels below 200 mg/dL
- C) Increasing insulin post-surgery
- D) No impact on infection rates

A

Answer: B) Preventing infections with glucose levels below 200 mg/dL

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32
Q
  1. Which of the following is a common side effect of aminoglycosides?
    • A) Ototoxicity
    • B) Increased heart rate
    • C) Gastrointestinal upset
    • D) Seizures
A

Answer: A) Ototoxicity

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33
Q
  1. Which antibiotic class is typically reserved for resistant infections in hospital settings?
    • A) Cephalosporins
    • B) Penicillins
    • C) Carbapenems
    • D) Metronidazole
A

Answer: C) Carbapenems

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34
Q
  1. What is the minimum inhibitory concentration (MIC) in relation to antibiotics?
    • A) The time it takes for antibiotics to reach the bloodstream
    • B) The lowest concentration of an antibiotic that inhibits visible bacterial growth
    • C) The concentration at which an antibiotic becomes ineffective
    • D) The maximum concentration tolerated by the patient
A

Answer: B) The lowest concentration of an antibiotic that inhibits visible bacterial growth

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35
Q

. Which of the following are common hospital-acquired infections? (Select all that apply)
- A) Urinary catheter-associated UTI
- B) Surgical site infections
- C) Appendicitis
- D) Hospital-acquired pneumonia

A

Answer: A) Urinary catheter-associated UTI, B) Surgical site infections, D) Hospital-acquired pneumonia

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35
Q

Which of the following are common risk factors for developing hospital-acquired infections (HAI)? (Select all that apply)
- A) Older age
- B) Short hospital stays
- C) Multiple chronic illnesses
- D) Direct contact with contaminated surfaces

A

Answer: A) Older age, C) Multiple chronic illnesses, D) Direct contact with contaminated surfaces

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36
Q

Which of the following infections are associated with central line use? (Select all that apply)
- A) Central line-associated sepsis
- B) Urinary catheter-associated UTI
- C) Surgical site infections
- D) Bloodstream infections

A

Answer: A) Central line-associated sepsis, D) Bloodstream infections

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37
Q

Which antibiotics are effective against gram-positive bacteria? (Select all that apply)
- A) Vancomycin
- B) Penicillin
- C) Ciprofloxacin
- D) Gentamycin

A

Answer: A) Vancomycin, B) Penicillin

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38
Q

Which bacteria are often responsible for causing surgical site infections (SSI)? (Select all that apply)
- A) Staphylococcus aureus
- B) Escherichia coli
- C) Pseudomonas aeruginosa
- D) Streptococcus

A

Answer: A) Staphylococcus aureus, C) Pseudomonas aeruginosa, D) Streptococcus

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39
Q

What are some common risk factors for surgical site infections (SSI)? (Select all that apply)
- A) Overweight
- B) Immunocompromised status
- C) Short surgery duration
- D) Smoking

A

Answer: A) Overweight, B) Immunocompromised status, D) Smoking

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40
Q

Which of the following factors increase the risk of surgical site infections (SSI)? (Select all that apply)
- A) Poor wound hygiene
- B) Lack of antibiotic prophylaxis
- C) Short surgery duration
- D) Older age

A

Answer: A) Poor wound hygiene, B) Lack of antibiotic prophylaxis, D) Older age

41
Q

Which of the following antibiotics require redosing in prolonged surgeries? (Select all that apply)
- A) Cefazolin
- B) Vancomycin
- C) Metronidazole
- D) Penicillin

A

Answer: A) Cefazolin, B) Vancomycin

42
Q

Which of the following are strategies to prevent hospital-acquired infections (HAI)? (Select all that apply)
- A) Hand hygiene
- B) Proper sterile technique during surgery
- C) Limiting hospital stays
- D) Regular staff training on infection control

A

Answer: A) Hand hygiene, B) Proper sterile technique during surgery, D) Regular staff training on infection control

43
Q

What are adverse reactions associated with fluoroquinolones? (Select all that apply)
- A) Cartilage damage
- B) Tendon rupture
- C) Nephrotoxicity
- D) QT interval prolongation

A

Answer: A) Cartilage damage, B) Tendon rupture, D) QT interval prolongation

44
Q

. Which conditions could lead to increased hospital-acquired infections (HAI)? (Select all that apply)
- A) Lack of infection control practices
- B) High pathogen prevalence in the community
- C) Use of antibiotics during surgery
- D) Infrequent cleaning of hospital environments

A

Answer: A) Lack of infection control practices, B) High pathogen prevalence in the community, D) Infrequent cleaning of hospital environments

45
Q

What are the adverse effects of vancomycin? (Select all that apply)
- A) Red man syndrome
- B) redness at injection site
- C) Rash
- D) Nephrotoxicity

A

Answer: A) Red man syndrome, B) redness at injection site, D) Nephrotoxicity

46
Q

. Which of the following symptoms indicate the presence of surgical site infections (SSI)? (Select all that apply)
- A) Redness
- B) Fever
- C) Pain at the site of incision
- D) Increased range of motion

A

Answer: A) Redness, B) Fever, C) Pain at the site of incision

47
Q

What are some methods to prevent surgical site infections (SSI)? (Select all that apply)
- A) Administering prophylactic antibiotics
- B) Maintaining proper sterile techniques
- C) Ensuring shorter surgery durations
- D) Limiting preoperative fasting

A

Answer: A) Administering prophylactic antibiotics, B) Maintaining proper sterile techniques

48
Q

Which of the following factors are commonly associated with an increased risk of hospital-acquired infections (HAI)? (Select all that apply)
- A) Prolonged hospital stays
- B) Inadequate infection control practices
- C) Older age
- D) High immune system activity

A

Answer: A) Prolonged hospital stays, B) Inadequate infection control practices, C) Older age

49
Q

Which of the following recommendations are part of the Guidelines for the Prevention of Surgical Site Infection (2017)? (Select all that apply)
- A) Administer parenteral antibiotics when indicated
- B) Achieve perioperative glucose levels below 200 mg/dL
- C) Soak prosthetic devices in antibiotic solution
- D) Use alcohol-based antiseptic for intraoperative skin preparation

A

Answer: A) Administer parenteral antibiotics when indicated, B) Achieve perioperative glucose levels below 200 mg/dL, D) Use alcohol-based antiseptic for intraoperative skin preparation

50
Q

Which recommendations are given for the use of non-parenteral antibiotics during surgery?** (Select all that apply)
- A) No recommendation for antibiotic irrigation
- B) No recommendation for soaking prosthetic devices in antibiotic solution
- C) Antibiotic ointments should be applied to the incision
- D) Alcohol-based antiseptics are preferred for skin preparation

A

Answer: A) No recommendation for antibiotic irrigation, B) No recommendation for soaking prosthetic devices in antibiotic solution

51
Q

Which surgical site infection (SSI) is most likely to occur after gastrointestinal surgery?
- A) Superficial incisional SSI
- B) Deep incisional SSI
- C) Organ or space SSI
- D) Central line-associated bloodstream infection (CLABSI)

A

Answer: C) Organ or space SSI

52
Q

Which of the following is the primary mechanism by which aminoglycosides achieve bacterial kill?
- A) Disruption of bacterial cell wall synthesis
- B) Inhibition of ribosomal protein synthesis
- C) Disruption of DNA replication
- D) Prevention of folic acid synthesis

A

Answer: B) Inhibition of ribosomal protein synthesis

53
Q

. What is the major benefit of utilizing the shortest possible course of antibiotic therapy during surgery?
- A) Reduces resistance to antibiotics
- B) Minimizes cost of antibiotics
- C) Increases patient compliance
- D) Prevents postoperative complications

A

Answer: A) Reduces resistance to antibiotics

54
Q

Which of the following infections is associated with prolonged mechanical ventilation?
- A) Central line-associated bloodstream infection (CLABSI)
- B) Ventilator-associated pneumonia (VAP)
- C) Urinary catheter-associated UTI
- D) Surgical site infection

A

Answer: B) Ventilator-associated pneumonia (VAP)

55
Q

Which cephalosporin generation provides the broadest spectrum of coverage against gram-negative bacteria?
- A) First generation
- B) Second generation
- C) Third generation
- D) Fourth generation

A

Answer: D) Fourth generation

56
Q

Which bacteria are most likely to exhibit resistance due to altered penicillin-binding proteins?
- A) Escherichia coli
- B) Streptococcus pneumoniae
- C) Staphylococcus aureus
- D) Klebsiella pneumoniae

A

Answer: B) Streptococcus pneumoniae

57
Q

Which factor increases the likelihood of methicillin-resistant Staphylococcus aureus (MRSA) colonization in hospital settings?
- A) Prior use of carbapenems
- B) Shorter hospital stay
- C) Use of non-invasive procedures
- D) Prolonged antibiotic use

A

Answer: D) Prolonged antibiotic use

58
Q

Which antibiotic mechanism is responsible for inhibiting bacterial DNA gyrase and topoisomerase IV?
- A) Aminoglycosides
- B) Fluoroquinolones
- C) Beta-lactams
- D) Glycopeptides
Answer: B)

A

Answer: B) Fluoroquinolones

59
Q

Why are patients on mechanical ventilators at increased risk for ventilator-associated pneumonia?
- A) Constant exposure to antibiotics
- B) Inability to clear secretions effectively
- C) High oxygen concentration in the lungs
- D) Limited mobility in hospital beds

A

Answer: B) Inability to clear secretions effectively

60
Q

. Which of the following is NOT an appropriate strategy for preventing hospital-acquired Clostridium difficile infections?
- A) Reducing unnecessary use of broad-spectrum antibiotics
- B) Using alcohol-based hand sanitizers to kill spores
- C) Isolating infected patients
- D) Practicing enhanced environmental cleaning

A

Answer: B) Using alcohol-based hand sanitizers to kill spores

61
Q

What is the primary difference between cefazolin (1st generation) and cefepime (4th generation)?
- A) Cefazolin is more effective against gram-negative organisms
- B) Cefepime penetrates the blood-brain barrier better than cefazolin
- C) Cefazolin is the drug of choice for gonorrhea
- D) Cefepime has more severe adverse effects

A

Answer: B) Cefepime penetrates the blood-brain barrier better than cefazolin

62
Q

. Why is redosing of antibiotics necessary during long surgeries?
- A) To avoid bacterial resistance
- B) To maintain the minimum inhibitory concentration (MIC)
- C) To counteract effects of anesthesia
- D) To prevent postoperative fever

A

Answer: B) To maintain the minimum inhibitory concentration (MIC)

63
Q

Which of the following antibiotics can cause nephrotoxicity and ototoxicity, especially in older adults?
- A) Ciprofloxacin
- B) Vancomycin
- C) Gentamycin
- D) Metronidazole

A

Answer: C) Gentamycin

64
Q

What is the role of beta-lactamase inhibitors when combined with beta-lactam antibiotics?
- A) They increase bacterial permeability to the drug
- B) They prevent bacterial enzyme-mediated antibiotic destruction
- C) They inhibit bacterial DNA replication
- D) They increase the dosage of the antibiotic required for efficacy

A

Answer: B) They prevent bacterial enzyme-mediated antibiotic destruction

65
Q
  1. Which of the following represents an “organ or space” SSI?
    • A) Infection limited to the skin surface
    • B) Infection deep in the muscle layer
    • C) Infection occurring in the peritoneal cavity
    • D) Infection at the incision site
A

Answer: C) Infection occurring in the peritoneal cavity

66
Q

Which strategy is commonly used to prevent ventilator-associated pneumonia (VAP)?
- A) Frequent hand washing
- B) Elevating the head of the bed
- C) Using antibiotics prophylactically
- D) Extending ventilation duration

A

Answer: B) Elevating the head of the bed

67
Q

Which of the following is NOT typically used for perioperative prophylaxis in surgery?
- A) Cefazolin
- B) Metronidazole
- C) Vancomycin
- D) Clindamycin

A

Answer: D) Clindamycin

68
Q

Why is metronidazole effective in treating anaerobic infections?
- A) It targets the bacterial cell wall
- B) It produces toxic metabolites in anaerobic bacteria
- C) It binds to bacterial ribosomes
- D) It prevents bacterial DNA replication

A

Answer: B) It produces toxic metabolites in anaerobic bacteria

69
Q

Which of the following organisms is most commonly associated with biofilm formation on medical devices?
- A) Escherichia coli
- B) Staphylococcus epidermidis
- C) Streptococcus pneumoniae
- D) Klebsiella pneumoniae

A

Answer: B) Staphylococcus epidermidis

70
Q

Which antibiotic class inhibits bacterial cell wall synthesis and is frequently used as prophylaxis during surgery?
- A) Beta-lactams
- B) Aminoglycosides
- C) Fluoroquinolones
- D) Tetracyclines

A

Answer: A) Beta-lactams

71
Q

. What is the most effective method to prevent the spread of Clostridium difficile in a healthcare setting?
- A) Using alcohol-based hand sanitizers
- B) Administering probiotics
- C) Proper handwashing with soap and water
- D) Preventive use of antibiotics

A

Answer: C) Proper handwashing with soap and water

72
Q

What is the primary target for penicillin’s bactericidal action?
- A) Bacterial ribosomes
- B) Bacterial DNA
- C) Bacterial cell walls
- D) Bacterial RNA

A

Answer: C) Bacterial cell walls

73
Q

Which surgical antibiotic class has been associated with an increased risk of colitis?
- A) Cephalosporins
- B) Fluoroquinolones
- C) Aminoglycosides
- D) Tetracyclines

A

Answer: A) Cephalosporins

74
Q

What is the recommended prophylactic antibiotic for a patient allergic to penicillin undergoing surgery?
- A) Vancomycin
- B) Cefazolin
- C) Amoxicillin
- D) Clindamycin

A

Answer: D) Clindamycin

75
Q

Which of the following is a major cause of postoperative infections following orthopedic surgery?
- A) MRSA
- B) Escherichia coli
- C) Streptococcus pyogenes
- D) Clostridium difficile

A

Answer: A) MRSA

76
Q

. Which bacteria are commonly involved in urinary catheter-associated infections?
- A) Escherichia coli
- B) Pseudomonas aeruginosa
- C) Enterococcus faecalis
- D) All of the above

A

Answer: D) All of the above

77
Q
  1. Which antibiotic is most commonly recommended for preoperative prophylaxis in patients undergoing colorectal surgery?
    • A) Ciprofloxacin
    • B) Metronidazole
    • C) Vancomycin
    • D) Cefoxitin
A

Answer: B) Metronidazole

78
Q

What is the major role of oxygenation in preventing surgical site infections?
- A) Inhibiting bacterial replication
- B) Promoting wound healing
- C) Enhancing immune function in tissues
- D) Directly killing bacteria

A

Answer: B) Promoting wound healing

79
Q

Why are beta-lactam antibiotics often ineffective against MRSA?
- A) MRSA produces beta-lactamase
- B) MRSA alters penicillin-binding proteins
- C) MRSA has thicker cell walls
- D) MRSA has altered DNA gyrase

A

Answer: B) MRSA alters penicillin-binding proteins

80
Q

Which factor significantly increases the risk of Clostridium difficile infection following surgery?
- A) Preoperative fasting
- B) Postoperative opioid use
- C) Use of broad-spectrum antibiotics
- D) Use of localized anesthetics

A

Answer: C) Use of broad-spectrum antibiotics

81
Q

. Which of the following is a key adverse effect associated with the use of carbapenems?
- A) Prolongation of the QT interval
- B) Seizures
- C) Hemolytic anemia
- D) Hepatotoxicity
Answer: B) Seizures

A

Answer: B) Seizures

this is due to binding with depakote, so situational

82
Q

Why is the use of newer antibiotics generally discouraged unless absolutely necessary?
- A) They have higher toxicity levels
- B) They promote resistance to older, more common antibiotics
- C) They are too expensive for regular use
- D) They take longer to administer

A

Answer: B) They promote resistance to older, more common antibiotics

83
Q

Which bacterial infection is most commonly acquired in a hospital setting and associated with prolonged antibiotic use?
- A) Clostridium difficile
- B) Escherichia coli
- C) Streptococcus pneumoniae
- D) Staphylococcus aureus

A

Answer: A) Clostridium difficile

84
Q

Which of the following are common pathogens in surgical site infections (SSI) following orthopedic surgery?
- A) Enterococcus faecalis
- B) Staphylococcus aureus
- C) Clostridium difficile
- D) Pseudomonas aeruginosa

A

Answer: B) Staphylococcus aureus

85
Q

Why is vancomycin the drug of choice for treating MRSA infections in hospitals?
- A) It inhibits bacterial protein synthesis
- B) It inhibits bacterial DNA replication
- C) It inhibits bacterial cell wall synthesis
- D) It targets bacterial ribosomes

A

Answer: C) It inhibits bacterial cell wall synthesis

86
Q

. Which of the following contribute to the development of ventilator-associated pneumonia (VAP)? (Select all that apply)
- A) Inability to clear respiratory secretions
- B) Prolonged mechanical ventilation
- C) Overuse of broad-spectrum antibiotics
- D) Use of non-invasive ventilation techniques

A

Answer: A) Inability to clear respiratory secretions, B) Prolonged mechanical ventilation, C) Overuse of broad-spectrum antibiotics

87
Q

Which of the following conditions increase the risk of surgical site infections (SSI)? (Select all that apply)
- A) Diabetes
- B) Obesity
- C) Immunosuppression
- D) Prolonged surgery duration

A

Answer: A) Diabetes, B) Obesity, C) Immunosuppression, D) Prolonged surgery duration

88
Q

Which of the following antibiotics can cause “red man syndrome” as a side effect? (Select all that apply)
- A) Vancomycin
- B) Ciprofloxacin
- C) Metronidazole
- D) None of the above

A

Answer: A) Vancomycin

89
Q

Which of the following antibiotics are effective against anaerobic infections? (Select all that apply)
- A) Metronidazole
- B) Clindamycin
- C) Vancomycin
- D) Amoxicillin

A

Answer: A) Metronidazole, B) Clindamycin

90
Q

Which bacteria are common causes of bloodstream infections associated with central lines? (Select all that apply)
- A) Coagulase-negative staphylococci
- B) Enterococcus faecalis
- C) Klebsiella pneumoniae
- D) Streptococcus pneumoniae

A

Answer: A) Coagulase-negative staphylococci, B) Enterococcus faecalis, C) Klebsiella pneumoniae

91
Q

Which of the following are mechanisms by which bacteria acquire resistance to antibiotics? (Select all that apply)
- A) Mutation of target sites
- B) Efflux pump overexpression
- C) Horizontal gene transfer
- D) Capsule formation

A

Answer: A) Mutation of target sites, B) Efflux pump overexpression, C) Horizontal gene transfer

92
Q

Which of the following antibiotic classes inhibit bacterial protein synthesis? (Select all that apply)
- A) Aminoglycosides
- B) Macrolides
- C) Beta-lactams
- D) Tetracyclines

A

Answer: A) Aminoglycosides, B) Macrolides, D) Tetracyclines

93
Q

What are some ways that hospital staff can prevent the spread of Clostridium difficile? (Select all that apply)
- A) Isolating infected patients
- B) Using alcohol-based hand sanitizers
- C) Cleaning rooms with bleach-based solutions
- D) Wearing personal protective equipment (PPE)

A

Answer: A) Isolating infected patients, C) Cleaning rooms with bleach-based solutions, D) Wearing personal protective equipment (PPE

94
Q

Which of the following factors contribute to the rise of antibiotic-resistant organisms in hospitals? (Select all that apply)
- A) Inappropriate use of antibiotics
- B) Over-prescription of antibiotics
- C) Delayed infection control practices
- D) Lack of patient education

A

Answer: A) Inappropriate use of antibiotics, B) Over-prescription of antibiotics, C) Delayed infection control practices

95
Q

Which of the following bacteria are frequently implicated in catheter-associated urinary tract infections (CAUTI)? (Select all that apply)
- A) Escherichia coli
- B) Proteus mirabilis
- C) Enterococcus faecalis
- D) Staphylococcus aureus

A

Answer: A) Escherichia coli, B) Proteus mirabilis, C) Enterococcus faecalis

96
Q

Which of the following surgical procedures are at higher risk of postoperative infection? (Select all that apply)
- A) Abdominal surgery
- B) Hip replacement surgery
- C) Neurosurgery
- D) Cardiac surgery

A

Answer: A) Abdominal surgery, B) Hip replacement surgery, D) Cardiac surgery

97
Q

. Which of the following factors enhance bacterial resistance in hospital-acquired infections? (Select all that apply)
- A) Incomplete antibiotic courses
- B) Excessive use of broad-spectrum antibiotics
- C) Infrequent hand hygiene by healthcare workers
- D) Use of multiple antibiotics in combination therapy

A

Answer: A) Incomplete antibiotic courses, B) Excessive use of broad-spectrum antibiotics, C) Infrequent hand hygiene by healthcare workers

98
Q

Which organisms are commonly responsible for surgical site infections (SSI) after gastrointestinal surgery? (Select all that apply)
- A) Bacteroides fragilis
- B) Escherichia coli
- C) Clostridium difficile
- D) Staphylococcus aureus

A

Answer: A) Bacteroides fragilis, B) Escherichia coli

99
Q

Which of the following represent effective methods to reduce the spread of multi-drug resistant organisms (MDROs) in hospital settings? (Select all that apply)
- A) Regular surveillance cultures
- B) Antimicrobial stewardship programs
- C) Isolation of colonized patients
- D) Routine use of alcohol-based hand sanitizers

A

Answer: A) Regular surveillance cultures, B) Antimicrobial stewardship programs, C) Isolation of colonized patients