Haemopoiesis Flashcards
1
Q
Causes of massive splenomegaly
A
Chronic myeloid leukaemia
Myelofibrosis
Malaria
Schistosomiasis
2
Q
Moderate
A
Lymphoma Leukaemia Myeloproliferative disorders Liver cirrhosis - portal hypertension Glandular fever - EBV
3
Q
Mild splenomegaly
A
Infective hepatitis
Endocarditis
Infiltrative disorders - sarcoidosis
Autoimmune- autoimmune haemolytic anaemia, SLE
4
Q
Globing Gene
A
Chromosome 11 and 16
5
Q
Red blood cell structure
A
Ankyrin connects Band 3 to spectrin to prevent flip flop
Band 4.1 connects spectrin to glycophorin A - restricts lateral movement and flip flop