Haemopoiesis Flashcards
1
Q
What is the lifespan of RBCs
A
120 days
2
Q
What is the lifespan of Neutrophils?
A
7-8 hours
3
Q
What is the lifespan of Platelets?
A
7-10 days
4
Q
What is the precursor cell of platelets?
A
Megakaryocytes
5
Q
What does “-blast” mean?
A
nucleated precursor cell:
- erythroblast = RBC precursor
- myeloblast = WBC precursor
6
Q
During development, what is the first site of erythropoiesis?
A
Yolk sac
7
Q
When during embryological development, does bone marrow start carrying out haemopoiesis?
A
16 weeks
8
Q
What are the bone forming cells, and bone destroying (phagocytic cells)?
A
Osteoblasts - bone forming
Osteoclasts - bone destroying
9
Q
What antigen is expressed by haemopoietic stem cells which can be detected on immunophenotyping?
A
CD34
