Haemopoiesis Flashcards
Haemopoiesis
Process of blood cell production, differentiation, and development.
Cytokines
Regulatory proteins that control haematopoiesis
Bone Marrow
Spongy tissue in bones where blood cells are produced
Yellow Marrow
Inactive Marrow composed of adipose tissue
Red Marrow
Active Marrow producing blood cells
Haematopoietic Progenitor Cells
Cells in the bone marrow that give rise to blood cells
Hematopoietic stem cells
Multi-function cells that differentiate into specialized blood cells
CD34+
Marker on haemopoietic stem cells surface for identification
CFU-GEMM
Earliest stem cell in specific linage haematopoiesis
GM-CSF
Growth factor promoting differentiation into neutrophils, monocytes, etc
Thrombopoietin (TPO)
Hormone promoting megakaryopoiesis for platelet production
Interleukin (ILS)
Proteins produced by leukocytes, influencing blood cell production
Cytocine
Regulates blood cell maturation
growth Factors
Stimulate cell proliferation and differentiation