Haemoglobinopathies Flashcards
1
Q
sickle cell crisis management
A
oxygen
opiates
rehydrate
transfusion
exchange transfusion if severe complications (eg neuro)
2
Q
sickle cell crisis prophylaxis drug
bonus points for MoA
A
hydroxyurea
increased production of HbF
3
Q
Definitive diagnostic test for sickle cell anaemia
A
haemoglobin electrophoresis
3
Q
What are Howell Jolly bodies
and what causes them
A
erythrocytes with little bits of DNA left in then
caused by hyposplenism which by happen in sickle due to splenic infarcts
4
Q
A