Haemoglobinopathies Flashcards

1
Q

sickle cell crisis management

A

oxygen
opiates
rehydrate
transfusion
exchange transfusion if severe complications (eg neuro)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

sickle cell crisis prophylaxis drug

bonus points for MoA

A

hydroxyurea

increased production of HbF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Definitive diagnostic test for sickle cell anaemia

A

haemoglobin electrophoresis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are Howell Jolly bodies

and what causes them

A

erythrocytes with little bits of DNA left in then

caused by hyposplenism which by happen in sickle due to splenic infarcts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q
A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly