Haematology (Path guide) Flashcards
Peripheral Blood Films:
Outline the appearance, description of and underlying conditions of:
- Acanthocytes
- Basophilic RBC stippling
- Burr Cells
- Heinz Bodies
- Howel-Jolly Bodies
Peripheral Blood Films:
Outline the appearance, description of and underlying conditions of:
- Right Shift
- Rouleaux formation
- Schistocytes
Peripheral Blood Films:
Outline the appearance, description of and underlying conditions of:
- Leucoerythroblastic Anaemia
- Pelger Huet Cells
- Polychromasia
- Reticulocytosis
Anaemia:
What is the definition of, causes of, symptoms and signs and types of anaemia?
Iron Deficiency Anaemia:
Outline the Definition of, signs, blood film findings, causes and treatment of Iron Deficiency Anaemia
Anaemia of Chronic Disease:
Outline the aetiology, causes of and findings in Anaemia of Chronic Disease
Sideroblastic Anaemia:
Outline the aetiology, causes of and findings in Sideroblastic Anaemia
Interpretation of Plasma Iron Studies:
Outline the interpretation of Plasma Iron studies (Iron, TIBC and Ferritin) for:
- Iron Deficiency
- Anaemia of Chroic Disease
- Chronic Haemolysis
- Haemochromatosis
- Pregnancy
- Sideroblastic Anaemia
Mactocytic Anaemia:
What are the differnt types of Macrocytic Anaemia and blood film findings in Megaloblastic Anaemia?
Vitamin B12 Deficiency:
What is the aeitology, symptoms, investigations and management of Vitamin B12 deficiency?
Folate Deficiency:
What is the aeitology, symptoms, investigations and management of Folate Deficiency?
Haemolytic Anaemias
What is the definition of, features of and subclasses of Haemolytic Anaemia?
Membrane, Inherited, Haemolytic Anaemias
Outline the inheritance of, aeitiology of, diagnosis and treatment of the main Inherited Haemolytic Anaemias affecting membranes
Enzyme, Inherited, Haemolytic Anaemias
Outline the inheritance of, aeitiology of, diagnosis and treatment of the main Inherited Haemolytic Anaemias affecting Enzymes
Haemoglobinopathies, Inherited, Haemolytic Anaemias
Outline the inheritance of, aeitiology of, diagnosis and treatment of Sickle Cell Anaemia
Haemoglobinopathies, Inherited, Haemolytic Anaemias
Outline the inheritance, aeitiology, sympotoms, investigations and treatment of Thalassaemia (A & B)
Acquired Haemolytic Anaemias
Outline the main types of Immune Acquired Haemolytic Anaemias
(include features, causes and management)
Acquired Haemolytic Anaemias
Outline the main types of Non-Immune Acquired Haemolytic Anaemias
Haemostasis
Outline the main processes in forming a stable Haemostatic plug
Haemostasis
Outline the main steps of the Coagulation cascade
Haemostasis
- Outline the main phases of the coagulation cascade
- Name the main inhibitors of the coagulation cascade
- The tests for the Intrinsic, Extrinsic and Common Pathways, what they are for and what factor the pathways start with.
Bleeding Disorders
What are the main types of bleeding disorders?
What features are associated with them?
Vascualr Defects, Bleeding Disorders
What are the main types of vascular defects that cause bleeding disorders?
Platelet Defects, Bleeding Disorders
What are the main types of platelet defects that cause bleeding disorders?
Platelet Defects, Bleeding Disorders
What are the main features of Acute Immune Thrombocytopenia and Chronic Immune Thrombocytopenia?
Include:
- Peak age
- M:F Ratio
- Preceding infection
- Onset of sypmtoms
- Platlet count at presentation
- Duration
- Spontaneous remession
Coagulation Disorders
What are the main types of inherited Coagulation Disorders?
Coagulation Disorders
What are the main types of Acquired Coagulation Disorders?
Blood tests for Coagulation disorders:
Outline the results for INR, APTT, Thrombin time, Platelet count and Bleeding time for:
- Heparin
- DIC
- Liver Disease
- Platelet defect
- Vit K Deficiency
- Haemophilia
- vWF Disease
Venous Thrombosis
Outline the main risk factors for and causes of Venous Thromboembolism (VTE)
Treatment of VTE
Outline the treatment of VTE (both prophylaxis and primary)
Venous Thrombosis
What are the mechanisms of action of Heparin and Warfarin?
Target INR and protocol for raised INR
What are the main target INRs?
What is the protocol for raised INR of different levels?
Acute Leukaemia
Outline the clinical features of, Aetiology and Diagnosis of Acute Leukaemia
Acute Leukaemia
Outline the epidemiology, clinical features of, investigations and treatment of ALL and AML
Chronic Myeloid Leukaemia
Outline the epidemiology, clinical features of, investigations and treatment of CML
Outline the features of its different phases
Chronic Lymphocytic Leukaemia
Outline the epidemiology, clinical features of, investigations, prognostic factors, staging and treatment of CLL
Lymphoma
Outline the definition of Lymphoma and the areas that it can manifest
Hodgkin’s Lymphoma
Outline the treatment of Hodgkin’s Lymphoma and the main features of Stem Cell Transplants in treating malignancy
Hodgkin’s Lymphoma
Outline the epidemiology, clinical presentation, investigations and staging of Hodgkin’s Lymphoma
Non Hodgkins Lymphoma
Outline the classification of and main similarities of Non Hodgkins Lymphomas
Outline the Main features of T Cell Lymphomas
Non Hodgkins Lymphoma
Outline the features, histopathology and trreatment of B Cell Lymphomas, including:
- Burkitt’s Lymphoma
- Diffues Large B Cell Lymphoma
- Mantle Cell Lymphoma
- Follicular
- Mucoas Associated lymphoid tissue (MALT)
Multiple Myeloma
Outline the definition of, clincal features, investigations and treatment of Multiple Myeloma
Multiple Myeloma
Outline the M Spike, Bone Marrow, CRAB, Organ damage, and significance of:
- MGUS
- Smouldering MM
- Multiple Myeloma
