Haematology - Blood Films Flashcards
What can you see and what conidition is it associated with?
Acanthocytes aka Spur/Spike cells
Abetalipoproteinaemia, liver disease, hyposplenism
What can you see and what conidition is it associated with?
Basophilic stripping
Lead poisoning, megaloblastic anaemia, myelodysplasia
What can you see and what conidition is it associated with?
Burr cells aka echinocytes
Uraemia, GI bleeding, stomach carcinoma
What can you see and what conidition is it associated with?
Heinz Bodies
Glucose-6-phosphate dehydrogenase deficiency, chronic liver disease
What can you see and what conidition is it associated with?
Howell-Jolly body
Post-splenectomy, megaloblastic anaemia, hyposplenism (e.g. sickle cell, coeliac, UC/Crohn’s)
What can you see and what conidition is it associated with?
Pelger Huet
Congenital: Lamin B receptor mutation
Acquired: Myelogenous leukaemia
What can you see and what conidition is it associated with?
Polychromasia
Normocytic anaemia
What can you see and what conidition is it associated with?
Reticulocytes
Raised in haemolytic anaemias
Low in chemotherapy and aplastic anaemias
What can you see and what conidition is it associated with?
Rouleaux Formation
Multiple myeloma, diabetes mellitus, chronic inflammation
What can you see and what conidition is it associated with?
Schistocytes
Disseminated intravascular coagulation, thrombotic thrombocytopenic purpura, heart valve haemolysis
What can you see and what conidition is it associated with?
Spherocytes
Hereditary spherocytosis , haemolytic anaemia
What can you see and what conidition is it associated with?
Stomatocytes
hereditary stomatocytosis, high alcohol, liver disease
What can you see and what conidition is it associated with?
Target cells
Liver disease, thalassaemia (alpha,beta), hyposplenism
