haematology

Question 1

what is haemophilia A

Answer 1

deficiency of factor VIII

Question 2

what is haemophilia B

Answer 2

deficiency of factor IX

Question 3

presentation of haemophilia?

Answer 3

haemarthrosis
intracranial haemorrhage and cord bleeding in neonates
bleeding muscles
prolonged bleeding of gums

Question 4

blood tests in haemophilia- what do they show?

Answer 4

prolonged APTT

PT normal , bleeding time and thrombin time normal

Question 5

how would you treat a severe PE?

Answer 5

unfractioned heparin

Question 6

what causes prolongation of the PT?

Answer 6

Warfarin

factor VII

Question 7

what causes prolongation of the APTT

Answer 7

vWd

both haemophilias

Question 8

what causes prolongation of PT AND APTT

Answer 8

liver disease
vit K deficieny
DIC

Question 9

what can you use FFP for?

Answer 9

for correction of clotting abnormalities in those with reduced hepatic synthetic function , especially when about to undergo surgery

Question 10

what do you use to reverse warfarin?

Answer 10

vitamin K and prothrombin comnplex

Question 11

what does cryoprecipitate contain?

Answer 11

Factor VIII and fibrinogen