Haematology

Question 1

Possbile causes of neutrophilia?

Answer 1

Bacteral sepsis
inflammatory conditions
tissues damage due to infarction or trauma
clucocorticoid excess
Haematological malignancy - CML , Polycythaemia rubra vera and myelofibrosis

Question 2

possible casues of lymphocytosis

Answer 2

viral sepsis
intracellular bacterial sepsis
lymphoma
chronic lymphocytic leukemia

Question 3

possible causes of Eosinophilia

Answer 3

Parasitic infection
allergic disorder and atopy
Vasculitic conditions such a polyarteritis nodosa
addisons diseae
Eosinophilic myalgic syndorme
hypereosinophilic syndrome
acute interstitial nephritis

Question 4

possible causes of leucopenia

Answer 4

Viral sepsis
drugs= carbimazole ganciclovir, myelosuppressive agents
chloramphenicol,
Felty’s syndrome
SLE
Bone marrow infiltration by sepsis and malignancy

Question 5

Blood film

Answer 5

pencil cells - in iron deficiency anaemia
teardrop poikilocytosis- in myelofibrosis
spherocytes- in herediatary spherocytosis, autoimmune haemolytic anaemia
target cells - in liver diseae, iron deficiency, thalassemia
polychromasia- reflects a high reticulytes count