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BDS3 BAMS Special Care Dentistry > Haematology > Flashcards

Haematology Flashcards

1
Q

What is the problem with prescribing topical miconazole to a patient who is taking Warfarin ?

A

Potentiating bleed risk.

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2
Q

For a patient with moderate haemophilia, is factor cover required for supragingival scaling ?

A

No.

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3
Q

What factors does prothrombin time test (PT) measure ?

A

VIII, IX, XII, X, V, prothrombin and fibrinogen.

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4
Q

A patient has an elevated prothrombin time, what does this indicate ?

A

Bleeding tendency - higher INR.

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5
Q

INR can be calculated from what test value ?

A

Prothrombin time test.

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6
Q

A patient has liver disease and another is taking warfarin, what blood test will come back deranged ?

A

Prothrombin time test.

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7
Q

What factors does activated partial thromboplastin time test (aPTT) measure ?

A

VII, X, V, prothrombin and fibrinogen.

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8
Q

What is the difference between aPTT and PT tests ?

A

PT - more extensive testing, shows levels of more factors compared to APTT.

PT - time that it takes plasma to clot after the addition of phospholipid, tissue factor (factor III), and calcium.
aPTT - time it takes plasma to clot after the addition of a contact agent that fully activates factors XI, calcium and phospholipids.

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9
Q

Patient has haemophilia A, what blood test will come back deranged ?

A

Activated partial thromboplastin time test.

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10
Q

Is augmentation of factor levels required for patient with mild haemophilia A ?

A

Yes.

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11
Q

Is augmentation of factor levels required for patient with Type 3 VW disease ?

A

Yes.

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12
Q

Is augmentation of factor levels required for patient with Type 2a VW disease ?

A

Yes.

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13
Q

Is augmentation of factor levels required for patient with moderate haemophilia B ?

A

Yes.

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14
Q

How is Type 2 VW disease managed ?

A

With Factor VIII concentrate.

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15
Q

What is haemophilia A associated with ?

A

Factor VIII deficiency.

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16
Q

Is a single tooth extraction high or low risk ?

A

Low.

17
Q

Between what values is normal clotting factor % for patient with moderate Haemophilia A ?

A

1-5%

18
Q

What are the possible causes of microcytic anaemia ?

A

Iron deficiency, thalassemia.

19
Q

How is microcytic anaemia diagnosed from blood test results ?

A

Low MCV (less than 83 micron 3)

20
Q

Define microcytic anaemia.

A

Smaller RBC than normal due to lack of haemoglobin production.

21
Q

What are the possible causes of microcytic anaemia ?

A

Vit B12 and folate deficiency or retics.

22
Q

Define macrocytic anaemia.

A

Larger RBC than normal due to decreases DNA synthesis.

23
Q

How is macrocytic anaemia diagnosed from blood test results ?

A

(MCV) greater than 100 fL.

24
Q

What is normocytic anaemia caused by ?

A

Haemorrhage - GI bleed, trauma etc.

25
Q

How is normocytic anaemia diagnosed from blood test results ?

A

Low RBC count.

26
Q

What are retics ?

A

RBCs which are responsible for carrying oxygen around the body.

27
Q

What is high retics caused by ?

A

Bleed, liver or kidney disease, bone marrow - body trying to compensate for less RBCs.

28
Q

How is haemophilia type B (Christmas disease) defined ?

A

Factor IX deficiency.

29
Q

How is haemophilia type C defined ?

A

Factor XI deficiency (rare).

30
Q

How is thalassaemia defined ?

A

Reduced production of haemoglobin in bone marrow.

31
Q

How is VW Type 1 defined ?

A

VW factor deficiency.

32
Q

How is VW Type 2 defined ?

A

Normal amount of VW factor - just doesn’t work properly.

33
Q

How is VW disease managed ?

A

Desmopressin injections (DDVAP).

34
Q

How is haemophilia type A managed ?

A

Desmopressin injections (DDVAP).

35
Q

What is in minimum white blood cell count required to carry out dental treatment ?

A

1.

36
Q

What is the minimum platelet count required to carry out dental treatment in primary care setting ?

A

> 100.

37
Q

What is the minimum platelet count required to carry out dental treatment in secondary care setting ?

A

> 50.

38
Q

What is the normal blood glucose range ?

A

3.5-6mmol/L.

BDS3 BAMS Special Care Dentistry (1 decks)

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