haem gold Flashcards
1
Q
inhibitors of coagulation
A
protein c + s, antithrombin, tissue factor pathway inhibitor
2
Q
Causes of isolated prolonged APTT
A
12,11,9,8 (note 12 not clinically important)
vWF (can cause 8 deficiency)
Lupus anticoagulant
Heparin
3
Q
Isolated prolonged PT
A
Vit K (2,7,9,10)
Warfarin
Liver disease
Factor 7 deficiency
4
Q
Treatment for haemophilia
A
Tranexamic acid
Decompression
Recombinant factor replacement
5
Q
Tests for vWF
A
factor 8 (it stabilises this)
vWF antigen
vWF activity
vWF collagen binding
