haem

Question 1

pepper pot skull/lytic lesions

Answer 1

myeloma

Question 2

rouleaux formation

Answer 2

myeloma

Question 3

congo red staining

Answer 3

amyloid deposition of biopsied tissue in myeloma and AA amyloidosis

Question 4

reed sternberg cells

Answer 4

Hodgkins

Question 5

philadelphia chromosome (9;22 translocation)

Answer 5

CML

Question 6

atypical lymphocytes

Answer 6

EBV (mononucleosis)

Question 7

auer rods

Answer 7

AML

Question 8

bence-jones proteins

Answer 8

multiple myeloma

Question 9

itch after hot bath

Answer 9

polycythaemia rubra vera

Question 10

translocation (8;14)

Answer 10

burkitts lymphoma

Question 11

alcohol makes it worse - pain after drinking

Answer 11

hodgkins

Question 12

haemarthrosis

Answer 12

haemophilia

Question 13

reduced levels of factor IX (9)

Answer 13

haemophilia B

Question 14

young boy with reduced levels of factor VIII and increased APTT

Answer 14

haemophilia A

Question 15

schillings test

Answer 15

B12 deficiency

Question 16

smudge cells (immature lymphocytes)

Answer 16

CLL

Question 17

jak-2 mutation

Answer 17

PRV or essential thrombocytopenia

Question 18

nitroblue tetrazolium test

Answer 18

chronic granulomatous disease

Question 19

positive schumm’s test

Answer 19

intravascular haemolytic anaemia

Question 20

hair on end of skull on x-ray

Answer 20

major beta thalassaemia

Question 21

bite cells, blister cells and heinz bodies

Answer 21

G6PD deficiency

Question 22

russell bodies

Answer 22

chronic inflammation