H2: proteïne Flashcards

1
Q

DnaA intitiatie eiwitten

A

Herkenning v DnaA seq in origin;
Opent duplex op specif plaatsen in de OriC om DNA replicatie te initiëren

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2
Q

DnaC chaperone

A

Vereist voor aantrekking v DnaB binding aan OriC

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3
Q

DnaB helicase

A

DNA topoisomerase I; ontwindt dubbel-strengig DNA

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4
Q

HU,
FIS,
IHF,
DNA binding proteïns

A

DNA binding proteïnen; stimuleren initiatie

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5
Q

DnaG primase

A

Synthetiseert korte RNA primers

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6
Q

SSB

A

Enkelstrengig DNA binding proteïnen; beschermt matrijs + stabiliseert enkelstrengig DNA

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7
Q

DNA gyrase

A

DNA topoismerase II; heft torsionale spanning die ontstaat in DNA door ontwinding; verwijdert supercoils voorlopend aan replicatie vork

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8
Q

Dam methylase

A

Methyleert 5’(GATC) seq aan OriC en in andere delen van chromosoom

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9
Q

DNA polymerase III

A

DNA polymerase III synthetiseert DNA in leading en lagging strengen

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10
Q

DNA polymerase I

A

DNA polymerase I verwijdert RNA primers, en vult hiaten door nick translatie

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11
Q

DNA ligase

A

Verbindt covalent naburig gelegen Okazaki fragmenten

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12
Q

tu s eiwit

A

Vindt aan ter seq + voorkomt voortgang van replicatie vork- belemmert DnaB helicase

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