Gynecology Flashcards
Painful menstruation that affects normal activities
Dysmenorrhea
Primary dysmenorrhea is not due to ________ but is due to increased ___________
Not due to pelvic pathology
Due to increased prostaglandins
Painful uterine muscle wall activity
Secondary dysmenorrhea is due to __________, such as
Pelvic pathology Endometriosis Adenomyosis Leiomyomas Adhesions PID
Most common secondary cause of dysmenorrhea in younger patients. Most common secondary cause of dysmenorrhea in older pts
Endometriosis - younger
Adenomyosis - older
Diffuse pelvic pain right before or with onset of menses. May be associated with HA, n/v. Cramps usually last 1-3 days
Dysmenorrhea
Management of dysmenorrhea
NSAIDs first line
Local heat and vitamin E
Ovulation suppression - OCPs, etc.
Laparoscopy if medication fails to ro secondary causes
Absence of menstrual periodd
Amenorrhea
Light flow or spotting
Cryptomenorrhea
Heavy or prolonged bleeding at normal menstrual intervals
Menorrhagia
Irregular bleeding between expected menstrual cycles
Metorrhagia
Irregular, excessive bleeding between expected menstrual cycles
Menometrorrhagia
Infrequent menstruation with a prolonged cycle length > 35 days but < 6 mo
Oligomenorrhea
Frequency cycle interval (< 21 days)
Polymenorrhagia
Two etiologies of dysfunctional uterine bleeding (DUB)
- Chronic anovulation
2. Ovulatory
Cause of chronic anovulation
Unopposed estrogen
Seen especially with extremes of age
Workup of dysfunctional uterine bleeding includes:
- pelvic exam
- Hormone levels
- Transvaginal US
Management of acute severe bleeding with DUB
High dose IV estrogens or high dose OCPs
Management of anovulatory DUB
OCPs first line
Progesterone if estrogen CI
Definitive treatment for DUB
Hysterectomy - done if not responsive to medical treatment
Endometrial ablation - can be done if hysterectomy not wanted
Workup for amenorrhea
Pregnancy test
Serum prolactin
FSH, LH, TSH
Primary amenorrhea
Failure of menarche onset by age 15 y/o in the presence of secondary sex characteristics or 13 y/o in the absence of secondary sex characteristics
Secondary amenorrhea
Absence of menses for > 3 months in a pt with previously normal menstruction
Etiologies of secondary amenorreha
- Pregnancy (MC)
- Hypothalamus dysfunction
- Pituitary dysfunction
- Ovarian dysfunction
- Uterine disorder
Presence of endometrial tissue (stroma and gland) outside the endometrial (uterine) cavity. The ectopic endometrial tissue responds to cyclical hormonal changes
Endometriosis
Most common site for endometriosis
Ovaries
Also: posterior cul de sac, broad and uterosacral ligaments, rectosigmoid colon, bladder
Risk factors for endometriosis
Nulliparity
Family history
Early menarche
Signs/Symptoms of endometriosis
- Cyclic premenstrual pelvic pain
- Dysmenorrhea (painful menstruation)
- Dyspareunia (painful intercourse)
- Infertility
+/- low back pain
Diagnosis of endometriosis
Physical exam: normal, +/- fixed tender adnexal masses
Laparoscopy with biopsy - definitive treatment
Endometriosis involving the ovaries large enough to be considered a tumor, usually filled with old blood appearing chocolate-colored
Endometrioma (chocolate cyst)
Management of endometriosis
- Medical - ovulation suppression
OCPs + NSAIDs as needed
Leuprolide
Danazol (testosterone) - Surgical - laparoscopy with ablation or hysterectomy if no desire to conceive
Occur when follicles fail to rupture and continue to grow
Follicular ovarian cysts
Occurs when corpus luteum fails to degenerate after ovulation
Corpus luteal ovarian cysts
Excess hCG causes hyperplasia of the theca interna cells
Theca Lutein ovarian cyst
Signs/symptoms of ovarian cysts
Most are asymptomatic until they rupture, undergo torsion or become hemorrhagic
Menstrual changes, dyspareunia
Diagnosis of ovarian cysts
Pelvic US
Order hCG to r/o pregnancy
Smooth, thin-walled unilocular ovarian cyst on ultrasound
Follicular
Complex, thicker-walled with peripheral vascularity ovarian cyst on ultrasound
Luteal
Management of ovarian cysts
Most < 8 cm are functional and spontaneously resolve
NSAIDs, repeat US after 6 weeks
OCPs
Surgical intervention if > 8 cm or cysts found postmenopause
Two etiologies of vaginitis
- Infectious (bacterial, trichomoniasis, candida, cytolytic)
- Atrophic (postmenopausal, allergic rxn)
Copious discharge, watery grey-white “fish rotten” smell from vagina
Bacterial vaginosis
Malodorous discharge, frothy yellow green vaginal discharge, strawberry cervix
Trichomoniasis vaginosis
Thick curd-like/cottage cheese vaginal discharge
Candidiasis vaginosis
Non odorous vaginal discharge that is white to opaque
Cytolytic vaginosis
Diagnosis of bacterial vaginosis
Whiff test (fishy odor) Microscopic: epithelial cells covered with bacteria
Diagnosis of trichomoniasis vaginosis
Mobile protozoa on wet mount, WBCs
Diagnosis of candidiasis vaginosis
Hyphae, yeast and spores on KOH prep
Diagnosis of cytolytic vaginosis
Copious lactobacilli, large number of epithelial cells
Management of:
- Bacterial vaginosis
- Trichomoniasis
- Candidiasis vaginosis
- Cytolytic vaginosis
- Metronidazole or Clindamycin
- Metronidazole or Tinidazole
- Fluconazole, intravaginal antifungals
- Discontinue tampon usage, sodium bicarbonate (sitz baths)
Ascending infection of the upper reproductive tract (may lead to sepsis, ectopic pregnancy or infertility)
Pelvic inflammatory disease
Most common causes of PID
N gonorrhea
Chlamydia
People at increased risk of PID
Multiple sex partners Unprotected sex Prior PID Age 15-29 Nulliparous IUD placement
Pelvic/lower abdominal pain, dysuria, dyspareunia, vaginal discharge, nausea, vomiting
PID
Lower abdominal tenderness, fever. Purulent cervical discharge, +/- bleeding
PID
Cervical motion tenderness to palpation and rotation so severe they seem to rise off the bed
Chandelier sign
PID
Diagnosis of PID
- Primarily clinical
- Obtain hCG to r/o pregnancy
- Gram stain, WBC > 10,000
- Pelvic ultrasound if abscess suspected
- Laparoscopy if uncertain, severe disease or if no improvement with antibiotics