Gynecologic and Pregnancy Related Infections Part 2 Flashcards
1
Q
What kind of organism is N. gonorrhea?
A
- Gram neg diplococcus
2
Q
What agar grows N. gonorrhea?
A
- Thayer martin chocolate agar
3
Q
What is the virulence factor of N. gonorrhea?
A
- Pili for adherance
4
Q
What is needed often for the diagnosis of N. gonorrhea?
A
- PCR since it does not stain with Gram stain
5
Q
What is mycoplasma genitalium?
A
- Bacterial without cell walls
- Cause of non-gonococcal urethritis
6
Q
What is the empirical treatment of Gonorrhea and chlamydia?
A
- Ceftriaxone – IM
- Azithromycin – PO
- Doxycycline
7
Q
What is the MOA of ceftiraxone?
A
- Penetrates CSF with a long half life
- Broad spectrum –> 3rd gen cephalosporin
8
Q
What is the spectrum for azithromycin?
A
- Bacteria lacking cell walls and some anaerobes
9
Q
What is the MOA of azithromycin?
A
- Binds 50s subunit
10
Q
What is the MOA of doxycyline?
A
- Binds 30S subunit
11
Q
Is doxycycline safe in pregnancy?
A
- NO
12
Q
What are the most common causes of PID?
A
- N. gonorrhea and chlamydia trachomatis
13
Q
Where does PID begin?
A
- Vulva or vagina and spreads through the genital tract
14
Q
What is a bad end result of PID?
A
- Pyrosalpinx and tubo-ovarian abscess
15
Q
What is seen in a tubo-ovarian abscess?
A
- Adnexal mass
- Fever
- Increased WBC
- Abdominal-pelvic pain