Gyne II Flashcards
Where is the egg fertilized
Ampulla (the curvy part)
Name a cyst found @ fallopian tubes
Paratubal Cyst - Hydatids of Morgagni
Infection Sequelae in fallopian tubes
Pyosalpinx then Hydrosalpinx;
Whats follicularis
Lymphoid follicles after chronic inflammation
- found in walls of salpingitis
IUD Infection Cx
Actinomycosis; Actinomyoctic Salpingitis
- Gram +, Filamentous
Most common benign tumor of Fallopian tubes
Adenomatoid Tumor
- from mesothelium
Note this is rare; found in males too
Ovary Cells + Hormone production
- hormone stimulator too
Germinal Epithelium aka Mesothelium
Follicle: Theca + Granulosa Cells – Theca is outside
Germ Cells
Theca - gives estrogen precursor Testosterone
- in response to LH
Granulosa - makes Estrogen from Testosterone
- in response to FSH
What does sex cord cells give
Stroma cells like Granulosa, Theca, Sertoli, Leydig
Types of cysts in ovary [3]
and their hormonal properties;
Follicular Cyst - from unruptured follicles - mostly physiologic
Luteal Cysts - from corpus luteum
- yellow, fat, menstrual irregularities due to being hormonally active - alot of progesterone!!! + oestrogen
Polycystic Ovary
- Amenorrhea due to oestrogen secretion
- elevated androgens in female causes this
Germ Cell Tumors [4]
Dysgerminoma, same as Seminoma
- Radiosensitive
- lymphocyte inflitrate
Teratoma
- mature - can be malignant or benign (struma Ovarii)
- immature
Yolk Sac tumor (etraembryonal yolk sac)
Choriocarcinoma (placenta)
Ovarian Surface Epithelial Tumors
4 Differentiations types and 3 major Histologies
Name benign vs malignant of 2
- Endocervical - Mucous - Simple Columnar, Mucin Locules, intracytoplasmic
- Fallopian Tube (Tubal) - Serous - Simple Columnar, Ciliated, can have locules too
Cystadenoma vs Cystadenocarcinoma
Serous CAC is most common
- Endometrioid, resemble endometrium, Tubular Glands
- Urothelium (Brenner)
Histological features to classify borderline OET
Destructive Stromal Invasion ABSENCE
- mild atypia
- stratified
EOT
Mostly benign/malignant
Most malignant are…
Type 1 and Type 2 are…
Mostly benign
High Grade SEROUS
Low Grade vs High Grade
- from borderline tumor vs … lol
Sex Cord tumors [3]
Hormone action and Histological features
Most common?
Fibroma-Thecoma
- note theca cells produce androgens in response to LH; Granulosa forms oestrogen in response to FSH
- note is estrogen producing; yellow, fatty
Granulosa Cell Tumor [Most Common]
- oestrgen secreting - EPH, EC
- follicular pattern - Call-Exner bodies - to form gland-like structures
Sertoli-Leydig cell tumor
- secrete androgens
What are Sex Cord Tumors which secretes estrogen and whats the Cx
Thecoma and Granulosa Tumor both secrete oestrogen
- hence Endometrium HP - Endometrium Cancer
