gynaecomastia Flashcards
1
Q
causes
A
physiological: normal in puberty syndromes with androgen deficiency: Kallman's, Klinefelter's testicular failure: e.g. mumps liver disease testicular cancer e.g. seminoma secreting hCG ectopic tumour secretion hyperthyroidism haemodialysis drugs: see below
2
Q
A 22-year-old man presents to his general practitioner with enlarging breast tissue, which has been worsening over the last 3 months. He has also noticed a new lump on his left testicle. After a detailed history and examination, the general practitioner concludes that the man is likely to have testicular cancer.
starts with small lumps in males
What is the most likely diagnosis?
A
HCG secreting seminoma is a type of seminoma and is germ cell tumour. HCG secreting seminomas release human chorionic gonadotropin (HCG). This hormone can cause oestrogen production out of proportion with normal androgens, resulting in gynaecomastia.
