Gynaecology Flashcards
Definition of primary amenorrhea
By 13 years with no other evidence of pubertal development
By 15 years with some other signs of puberty
Age of puberty onset in girls
8-14 years
Age of puberty onset in boys
9-15 years
Structural causes of amenorrhoea
Imperforate hymen
Transverse vaginal septae
Vaginal agenesis
Absent uterus
FGM
Causes of secondary amenorrhoea
Pregnancy
Menopause
Hormonal contraception
Hypothalamic/pituitary pathology
PCOS
Ashermann’s syndrome
Thyroid pathology
Hyperprolactinaemia
Hormone tests for secondary Amenorrhoea
bHCG
FSH - high in primary ovarian failure
LH - high in PCOS
Prolactin
TFTs
Testosterone - PCOS, androgen insensitivity, congenital adrenal hyperplasia
Causes of menorrhagia
Dysfunctional uterine bleeding
Extremes of reproductive age
Fibroids
Endometriosis
PID
Copper coil
Anticoagulants
Bleeding disorders
PCOS
Connective tissue disorders
Management of menorrhagia
Tranexamic acid
Mefenamic acid
Mirena coil
COCP
Types of uterine fibroid
Intramural
Subserosal
Submucosal
Pedunculated
Presentation of uterine fibroids
Asymptomatic
Heavy menstrual bleeding
Abdominal pain, worse during menstruation
Bloating
Urinary/bowel symptoms
Deep dyspareunia
Reduced fertility
Management of fibroids <3cm
Mirena coil
Symptomatic management
COCP
Endometrial ablation
Resection during hysteroscopy
Management of fibroids >3cm
Symptomatic management
Mirena coil
Uterine artery embolisation
Myomectomy
Complications of uterine fibroids
Heavy menstrual bleeding
Reduced fertility
Miscarriage
Premature labour
Constipation
Urinary outflow obstruction
Torsion of fibroid
Potential aetiologies for endometriosis
Retrograde menstruation
Embryonic cells remaining outside the uterus
Lymphatic spread of endometrial cells
Presentation of endometriosis
Cyclical pelvic pain
Deep dyspareunia
Dysmenorrhoea
Infertility
Urinary symptoms
Bowel symptoms
Examination findings in endometriosis
Endometrial tissue visible on speculum examination
Fixed cervix
Tenderness in vagina, cervix & adnexa
Gold standard diagnostic investigation for endometriosis
Laparoscopy
Management of endometriosis
Analgesia
COCP
Medroxyprogestrone acetate injection
GnRH agonists
Laparoscopic ablation
Hysterectomy
Sex hormone profile in menopause
Oestrogen & progestrone low
LH & FSH high
Risks of HRT
Breast cancer
Endometrial cancer
VTE
Stroke & CAD
Contraindications for HRT
Undiagnosed abnormal bleeding
Endometrial hyperplasia
Breast cancer
Uncontrolled HTN
VTE
Liver disease
Active angina
Pregnancy
Which type of HRT for peri-menopausal women
Cyclical combined
Which type of HRT in post-menopausal women
Continuous combined
Types of ovarian cyst
Follicular cyst
Corpus luteum cyst
Serous cystadenoma
Mucinous cystadenoma
Endometrioma
Dermoid cyst
Sex cord-stromal tumour
Risk factors for ovarian malignancy
Increased age
Postmenopause
Early menarche
Late menopause
Nulliparity
Obesity
HRT
Smoking
BRCA1/BRCA2
Causes of raised CA125
Endometriosis
Fibroids
Adenomyosis
Pelvic infection
Liver disease
Pregnancy
Meig’s Syndrome triad
Ovarian fibroma
Pleural effusion
Ascites
What is Asherman’s Syndrome
Adhesions that form within the uterus
Presentation of Asherman’s Syndrome
Post recent dilatation & curettage, uterine surgery to endometriosis
Secondary amenorrhoea
Significantly lighter periods
Dysmenorrhoea
Gold standard investigation for Asherman’s syndrome
Hysteroscopy
What is cervical ectropion
Columnar epithelium of the endocervix extends out into the ectocervix
Presentation of cervical ectropion
Increased vaginal discharge
Vaginal bleeding
Dyspareunia
Postcoital bleeding
Management of cervical ectropion
Cautery with silver nitrate if problematic bleeding
What is vault prolapse
Occurs in women that have had a hysterectomy. The top of the vagina descends into the vagina
What is rectocele
Defect in the posterior vaginal wall that allows the rectum to prolapse forward into the vagina
What is cystocele
Defect in the anterior vaginal wall, allowing the bladder to prolapse backwards into the vagina
Risk factors for pelvic organ prolapse
Multiple vaginal deliveries
Instrumental/traumatic delivery
Advanced age
Obesity
Chronic respiratory disease
Chronic constipation
Presentation of pelvic organ prolapse
Dragging sensation in the pelvis
Feeling of something coming down into the vagina
Incontinence
Urgency
Retention
Constipation
Reduced sexual enjoyment
Altered sexual sensation
Painful intercourse
Grade 1 uterine prolapse
The lowest part is more than 1cm above the introitus