Gynae Cancers Flashcards
A 46-year-old woman with a history of cervical carcinoma treated by radiotherapy presents with a history of constant leaking of urine. She is required to wear a pad day and night. Choose the most appropriate diagnosis
a) Atrophic vaginitis
b) Carcinoma of the bladder
c) Detrusor instability
d) Vesicovaginal fistula
e) Urinary infection
d) Vesicovaginal fistula
Characteristic symptoms of ovarian carcinoma include
a) abdominal pain
b) weight change
c) abnormal uterine haemorrhage
d) vaginal discharge
e) none of the above
e) none of the above
The following statements relating to gynaecological cancer is CORRECT
a) 75% of patients with cancer of the vulva are under 50 years old
b) Nulliparous are at higher risk of Endometrial cancer than in parous women
c) Ovarian cancer presents characteristically with post-menopausal bleeding
d) Carcinoma of the vagina is a disease of the elderly woman only
e) Cervix cancer is the major cause of cancer related death in women
b) Nulliparous are at higher risk of Endometrial cancer than in parous women
Which of the following statements concerning ovarian carcinoma is CORRECT
a) Classically it presents early with bleeding
b) It occurs more commonly before the menopause
c) Human papilloma virus is implicated aetiologically
d) There is a lower incidence in women who have taken the combined oral contraceptive pill
e) There is a recognised association with high parity
d) There is a lower incidence in women who have taken the combined oral contraceptive pill
Risk factors for cervical intraepithelial neoplasia (CIN) include all of the following except
a) early age of first intercourse
b) smoking
c) presence of HPV on previous smears
d) more than one sexual partner
e) family history of cervical cancer
e) family history of cervical cancer
Serum CA125 is typically raised in association with:
a) Candidal vaginitis
b) Epithelial ovarian cancer
c) Spina bifida
d) Utero-vaginal prolapse
e) Vulvar carcinoma
b) Epithelial ovarian cancer
Which of the following are risk factors for endometrial cancer?
a) Type 1 Insulin dependent diabetes
b) Early menopause
c) Oral contraceptive pill
d) Combined oestrogen and progesterone HRT
e) Hereditary non polyposis coli cancer syndrome
e) Hereditary non polyposis coli cancer syndrome
Which of the following is NOT a risk factors for ovarian cancer?
a) Nulliparity
b) Smoking
c) Low socio economic class
d) Oral contraceptive pill
e) Non insulin dependent diabetes
d) Oral contraceptive pill
Which of the following is a risk factors for mucinous ovarian cancer?
a) Nulliparity
b) Smoking
c) Low socio economic class
d) Oral contraceptive pill
e) Non insulin dependent diabetes
b) Smoking
Which of the following is a risk factors for mucinous ovarian cancer?
a) Age
b) Smoking
c) Family History
d) Oral contraceptive pill
e) Pregnancy
b) Smoking
Which of the following statements is true regarding the investigation of women with post menopausal bleeding?
a) Vaginal ultrasound scan and dilatation and curettage have similar sensitivity for the detection of endometrial cancer
b) A woman with post menopausal bleeding who has an endometrial thickness of less than 4 mm has less than 1 chance / 1000 of having endometrial cancer
c) Approximately 1 / 10 women with endometrial cancer have an endometrial thickness of 4 mm or less
d) A, b + c are false
e) A, b, + c are true
e) A, b, + c are true
Which of the following statements regarding tumour markers are true?
a) Postmenopausal women with a complex ovarian mass with solid and cystic areas and a CA 125 of greater than 35 have a greater than 75% risk of having ovarian cancer
b) Serum alpha Fetoprotein is markedly elevated in young women with endodermal sinus tumours.
c) CA125 levels may be elevated in the presence of pregnancy, endometriosis and pelvic inflammation
d) a, b + c are false
e) a, b + c are true
e) a, b + c are true
The following are NOT common problems in the palliative care of women with advanced epithelial ovarian cancer
a) Abdominal discomfort due to ascites
b) Breathlessness and chest pain due to pleural effusion
c) Depression
d) Pain due to bony metastasis
e) Vomiting and abdominal pain due to small bowel obstruction
d) Pain due to bony metastasis
Ms NW, aged 19 years, has never been pregnant. She complains of sudden onset of pain with nausea. She is taking the combined oral contraceptive pill. On pelvic examination there is tender fullness of the right fornix and ultrasound examination shows an 8cm cystic and solid mass replacing the right ovary. Indicate the most likely diagnosis.
a) Corpus luteum cyst
b) Cystadenocarcinoma
c) Benign cystic teratoma
d) Follicular cyst
e) Granulosa cell tumour
c) Benign cystic teratoma
The following is true of invasive cancer of the vulva.
a) Melanoma is more common than adenocarcinoma
b) Squamous carcinomas of the vulva arise in approximately 3% of women following treatment of VIN3
c) It has a bimodal distribution by age
d) Is diagnosed in approximately 5% of women on removal of a VIN3 lesion
e) All of the above are correct
e) All of the above are correct