Gynae

Question 1

Risk of recurrence of NTD?

Answer 1

1/25

Question 2

Which statement about spontaneous miscarriage is correct?

Answer 2

Answer = in utero exposure to DES increases a womans chance of having a miscarriage

Question 3

Which congenital malformation is most likely to be associated with diabetes mellitus?

Answer 3

Isolated ventricular septal defect

Question 4

Adenocarcinoma of the cervix

A. Equally radiosensitive as SCC
B. Contraindicates ovarian conservation
C. Contraindicates exogenous oestrogen
D. All of the above

Answer 4

A

Question 5

The principal secretory product of polycystic ovaries is

Answer 5

Androstenedione

Question 6

Which medications can be associated with amenorrhea and galactorhoea?

Answer 6

Chlorpromazine and metoclopromide

Question 7

What is the lifetime risk of having an operation for genital prolapse?

Answer 7

1/9

Question 8

Treatment for granuloma inguinale?

Answer 8

Genital ulcerative disease caused by Klebsiella.

Treated with tetracycline

Question 9

Percentage of invasive cervical cancers missed on colposcopic examination without biopsy is estimated at?

Answer 9

27%

Question 10

True or false. Vulval melanoma occurs more frequently on the labia majora than minora?

Answer 10

False

Occurs more on the labia minora.

Question 11

% of population who have polycystic ovaries on ultrasound compared to % in PCOS patients?

Answer 11

20% population

75% PCOS

Question 12

Initial therapy for a vesicovaginal fistula?

Answer 12

Continuous catheter drainage

Question 13

Amenorrhea and galactorrhoea is least likely to be caused by?
Pituitary rumour
Chlorpromazine
Metoclopromide
Thyrotoxicosis

Answer 13

Thyrotoxicosis

Question 14

First investigation for ambiguous genitalia at birth?

Answer 14

Serum 17-OH progesterone

Question 15

Risk of admission to SCBU after c section at 37 weeks?

Answer 15

9%

Question 16

Is tetracycline for a recent immigrant with granuloma inguinale appropriate?

Answer 16

Yes

Question 17

True or false

With all available initiatives, the incidence of mother to child transmission of HIV should be reduced to 5%

Answer 17

False.

Should be to <1%

Question 18

True or false?
Pyramethamine/sulfadoxine is the most effective treatment for toxoplasmosis but spiramycin is theoretically less embryotoxic.

Answer 18

True.

Therefore spiramycin is used in t1 and p/s used in T2/3

Question 19

True or false?

A serious neonatal infection will occur in 5% of GBS carriers?

Answer 19

False.

0.5%

Question 20

Pulmonary embolism, LV failure and MS are all caused if pulmonary hypertension. True or false?

Answer 20

True

Question 21

The incidence of fetal infection after maternal seroconversion of CMV in pregnancy is?

Answer 21

50%

Question 22

Which is most likely to contribute to osteoporosis?
Phenytoin
Captopril
Amitryptiline
Warfarin

Answer 22

Phenytoin

Question 23

True or false? Hepatic impairment limits the use of bisphosphonates but they are well tolerated orally?

Answer 23

False

Question 24

Highest risk of VTE in the puerperium with...
Anti thrombin III deficiency
Factor V Leiden
Protein S deficiency
Hyperhomocysteinaemia

Answer 24

Anti thrombin III deficiency

Question 25

``` Which is least desirable in a pregnant woman with severe non-hypertrophic cardiomyopathy? Digoxin Frusemide Labetalol Prazosin ```

Answer 25

Labetalol

Question 26

True or false. | Ovulation cannot be induced with FSh in galactosemia

Answer 26

True

Question 27

True or false. | At an abdominal colposacropexy the upper end of the mesh should be attached between S1-S3 at more than one point?

Answer 27

True

Question 28

True or false. | Renal blood flow increased and serum urea and creatinine decrease in pregnancy

Answer 28

True

Question 29

True or false. Cyproterone acetate inhibits 5-alpha-reductase

Answer 29

False

Question 30

True or false. Oestrogen but not raloxifene has been shown to reduce atherosclerosis in primate studies

Answer 30

False

Question 31

True or false? Triphasic oral contraceptive pills containing 2nd generation progestogens are associated with a less favourable lipid profile than Monophasic preparations containing the same progestogens.

Answer 31

False

Question 32

``` Which antibiotic is least effective in the treatment of infections caused by bacteroides fragilis? Cefoxitin Clindamycin Gentamicin Metronidazole ```

Answer 32

Gentamicin

Question 33

True or false? Immunohistochemistry in Paget’s disease if the vulva suggests and eccrine gland origin of the cells

Answer 33

False

Question 34

Which artery should be ligated in order to remove the omentum?

Answer 34

Gastroepiploic artery

Question 35

Endometrial histological findings in PCOS

Answer 35

Crowding of straight tubular glands

Question 36

The photobiologic basis for action of CO2 laser on tissue is absorption of CO2 laser energy by?

Answer 36

Intracellular water

Question 37

Elevated fasting homocysteine is evidence of what?

Answer 37

Vitamin B6, B12 or folate deficiency as these are needed to metabolise homocysteine

Question 38

Endodermal sinus tumours of the ovary are associated with elevated concentrations of?

Answer 38

AFP

Question 39

Which of the following is not associated with an increase in non-androgen dependent hair (hypertrichosis)? a. Cyclosporin b. Phenytoin c. Diazoxide d. Ranitidine

Answer 39

D

Question 40

If a patient was born with a relative lack of the enzyme 17-alpha-hydroxylase, you would expect the patient to have?

Answer 40

Hypertension

Question 41

The normal upright anatomical position of the vaginal axis is?

Answer 41

Upwards and backwards at 135 degrees

Question 42

True or false? Immunohistochemistry in Paget’s disease suggests an eccrine gland origin of the cells

Answer 42

False