Gynae Flashcards

1
Q

Risk of recurrence of NTD?

A

1/25

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2
Q

Which statement about spontaneous miscarriage is correct?

A

Answer = in utero exposure to DES increases a womans chance of having a miscarriage

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3
Q

Which congenital malformation is most likely to be associated with diabetes mellitus?

A

Isolated ventricular septal defect

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4
Q

Adenocarcinoma of the cervix

A. Equally radiosensitive as SCC
B. Contraindicates ovarian conservation
C. Contraindicates exogenous oestrogen
D. All of the above

A

A

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5
Q

The principal secretory product of polycystic ovaries is

A

Androstenedione

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6
Q

Which medications can be associated with amenorrhea and galactorhoea?

A

Chlorpromazine and metoclopromide

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7
Q

What is the lifetime risk of having an operation for genital prolapse?

A

1/9

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8
Q

Treatment for granuloma inguinale?

A

Genital ulcerative disease caused by Klebsiella.

Treated with tetracycline

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9
Q

Percentage of invasive cervical cancers missed on colposcopic examination without biopsy is estimated at?

A

27%

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10
Q

True or false. Vulval melanoma occurs more frequently on the labia majora than minora?

A

False

Occurs more on the labia minora.

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11
Q

% of population who have polycystic ovaries on ultrasound compared to % in PCOS patients?

A

20% population

75% PCOS

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12
Q

Initial therapy for a vesicovaginal fistula?

A

Continuous catheter drainage

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13
Q
Amenorrhea and galactorrhoea is least likely to be caused by?
Pituitary rumour
Chlorpromazine
Metoclopromide
Thyrotoxicosis
A

Thyrotoxicosis

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14
Q

First investigation for ambiguous genitalia at birth?

A

Serum 17-OH progesterone

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15
Q

Risk of admission to SCBU after c section at 37 weeks?

A

9%

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16
Q

Is tetracycline for a recent immigrant with granuloma inguinale appropriate?

A

Yes

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17
Q

True or false

With all available initiatives, the incidence of mother to child transmission of HIV should be reduced to 5%

A

False.

Should be to <1%

18
Q

True or false?
Pyramethamine/sulfadoxine is the most effective treatment for toxoplasmosis but spiramycin is theoretically less embryotoxic.

A

True.

Therefore spiramycin is used in t1 and p/s used in T2/3

19
Q

True or false?

A serious neonatal infection will occur in 5% of GBS carriers?

A

False.

0.5%

20
Q

Pulmonary embolism, LV failure and MS are all caused if pulmonary hypertension. True or false?

A

True

21
Q

The incidence of fetal infection after maternal seroconversion of CMV in pregnancy is?

A

50%

22
Q
Which is most likely to contribute to osteoporosis?
Phenytoin
Captopril
Amitryptiline
Warfarin
A

Phenytoin

23
Q

True or false? Hepatic impairment limits the use of bisphosphonates but they are well tolerated orally?

A

False

24
Q
Highest risk of VTE in the puerperium with...
Anti thrombin III deficiency
Factor V Leiden
Protein S deficiency
Hyperhomocysteinaemia
A

Anti thrombin III deficiency

25
Q
Which is least desirable in a pregnant woman with severe non-hypertrophic cardiomyopathy?
Digoxin
Frusemide
Labetalol
Prazosin
A

Labetalol

26
Q

True or false.

Ovulation cannot be induced with FSh in galactosemia

A

True

27
Q

True or false.

At an abdominal colposacropexy the upper end of the mesh should be attached between S1-S3 at more than one point?

A

True

28
Q

True or false.

Renal blood flow increased and serum urea and creatinine decrease in pregnancy

A

True

29
Q

True or false. Cyproterone acetate inhibits 5-alpha-reductase

A

False

30
Q

True or false. Oestrogen but not raloxifene has been shown to reduce atherosclerosis in primate studies

A

False

31
Q

True or false? Triphasic oral contraceptive pills containing 2nd generation progestogens are associated with a less favourable lipid profile than Monophasic preparations containing the same progestogens.

A

False

32
Q
Which antibiotic is least effective in the treatment of infections caused by bacteroides fragilis?
Cefoxitin
Clindamycin
Gentamicin
Metronidazole
A

Gentamicin

33
Q

True or false? Immunohistochemistry in Paget’s disease if the vulva suggests and eccrine gland origin of the cells

A

False

34
Q

Which artery should be ligated in order to remove the omentum?

A

Gastroepiploic artery

35
Q

Endometrial histological findings in PCOS

A

Crowding of straight tubular glands

36
Q

The photobiologic basis for action of CO2 laser on tissue is absorption of CO2 laser energy by?

A

Intracellular water

37
Q

Elevated fasting homocysteine is evidence of what?

A

Vitamin B6, B12 or folate deficiency as these are needed to metabolise homocysteine

38
Q

Endodermal sinus tumours of the ovary are associated with elevated concentrations of?

A

AFP

39
Q

Which of the following is not associated with an increase in non-androgen dependent hair (hypertrichosis)?

a. Cyclosporin
b. Phenytoin
c. Diazoxide
d. Ranitidine

A

D

40
Q

If a patient was born with a relative lack of the enzyme 17-alpha-hydroxylase, you would expect the patient to have?

A

Hypertension

41
Q

The normal upright anatomical position of the vaginal axis is?

A

Upwards and backwards at 135 degrees

42
Q

True or false? Immunohistochemistry in Paget’s disease suggests an eccrine gland origin of the cells

A

False