Gynae Flashcards
Risk of recurrence of NTD?
1/25
Which statement about spontaneous miscarriage is correct?
Answer = in utero exposure to DES increases a womans chance of having a miscarriage
Which congenital malformation is most likely to be associated with diabetes mellitus?
Isolated ventricular septal defect
Adenocarcinoma of the cervix
A. Equally radiosensitive as SCC
B. Contraindicates ovarian conservation
C. Contraindicates exogenous oestrogen
D. All of the above
A
The principal secretory product of polycystic ovaries is
Androstenedione
Which medications can be associated with amenorrhea and galactorhoea?
Chlorpromazine and metoclopromide
What is the lifetime risk of having an operation for genital prolapse?
1/9
Treatment for granuloma inguinale?
Genital ulcerative disease caused by Klebsiella.
Treated with tetracycline
Percentage of invasive cervical cancers missed on colposcopic examination without biopsy is estimated at?
27%
True or false. Vulval melanoma occurs more frequently on the labia majora than minora?
False
Occurs more on the labia minora.
% of population who have polycystic ovaries on ultrasound compared to % in PCOS patients?
20% population
75% PCOS
Initial therapy for a vesicovaginal fistula?
Continuous catheter drainage
Amenorrhea and galactorrhoea is least likely to be caused by? Pituitary rumour Chlorpromazine Metoclopromide Thyrotoxicosis
Thyrotoxicosis
First investigation for ambiguous genitalia at birth?
Serum 17-OH progesterone
Risk of admission to SCBU after c section at 37 weeks?
9%
Is tetracycline for a recent immigrant with granuloma inguinale appropriate?
Yes
True or false
With all available initiatives, the incidence of mother to child transmission of HIV should be reduced to 5%
False.
Should be to <1%
True or false?
Pyramethamine/sulfadoxine is the most effective treatment for toxoplasmosis but spiramycin is theoretically less embryotoxic.
True.
Therefore spiramycin is used in t1 and p/s used in T2/3
True or false?
A serious neonatal infection will occur in 5% of GBS carriers?
False.
0.5%
Pulmonary embolism, LV failure and MS are all caused if pulmonary hypertension. True or false?
True
The incidence of fetal infection after maternal seroconversion of CMV in pregnancy is?
50%
Which is most likely to contribute to osteoporosis? Phenytoin Captopril Amitryptiline Warfarin
Phenytoin
True or false? Hepatic impairment limits the use of bisphosphonates but they are well tolerated orally?
False
Highest risk of VTE in the puerperium with... Anti thrombin III deficiency Factor V Leiden Protein S deficiency Hyperhomocysteinaemia
Anti thrombin III deficiency
Which is least desirable in a pregnant woman with severe non-hypertrophic cardiomyopathy? Digoxin Frusemide Labetalol Prazosin
Labetalol
True or false.
Ovulation cannot be induced with FSh in galactosemia
True
True or false.
At an abdominal colposacropexy the upper end of the mesh should be attached between S1-S3 at more than one point?
True
True or false.
Renal blood flow increased and serum urea and creatinine decrease in pregnancy
True
True or false. Cyproterone acetate inhibits 5-alpha-reductase
False
True or false. Oestrogen but not raloxifene has been shown to reduce atherosclerosis in primate studies
False
True or false? Triphasic oral contraceptive pills containing 2nd generation progestogens are associated with a less favourable lipid profile than Monophasic preparations containing the same progestogens.
False
Which antibiotic is least effective in the treatment of infections caused by bacteroides fragilis? Cefoxitin Clindamycin Gentamicin Metronidazole
Gentamicin
True or false? Immunohistochemistry in Paget’s disease if the vulva suggests and eccrine gland origin of the cells
False
Which artery should be ligated in order to remove the omentum?
Gastroepiploic artery
Endometrial histological findings in PCOS
Crowding of straight tubular glands
The photobiologic basis for action of CO2 laser on tissue is absorption of CO2 laser energy by?
Intracellular water
Elevated fasting homocysteine is evidence of what?
Vitamin B6, B12 or folate deficiency as these are needed to metabolise homocysteine
Endodermal sinus tumours of the ovary are associated with elevated concentrations of?
AFP
Which of the following is not associated with an increase in non-androgen dependent hair (hypertrichosis)?
a. Cyclosporin
b. Phenytoin
c. Diazoxide
d. Ranitidine
D
If a patient was born with a relative lack of the enzyme 17-alpha-hydroxylase, you would expect the patient to have?
Hypertension
The normal upright anatomical position of the vaginal axis is?
Upwards and backwards at 135 degrees
True or false? Immunohistochemistry in Paget’s disease suggests an eccrine gland origin of the cells
False
