GYN Onc Staging Flashcards

1
Q

Staging for GTN (2009 FIGO)

Stage I

A

Disease confined to uterus

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2
Q

Staging for GTN (2009 FIGO)

Stage II

A

Disease outside the uterus but confined to genital structures (vagina, adnexa)

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3
Q

Staging for GTN (2009 FIGO)

Stage III

A

Metastasis to the lungs, with or without genital involvement

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4
Q

Staging for GTN (2009 FIGO)

Stage IV

A

Other metastatic sites (outside lungs and genital structures)

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5
Q

Staging for Cervical Cancer

Stage IA

A

Stage I: strictly confined to cervix

IA: invasive carcinoma that can be diagnosed with microscope only, maximum depth of invasion <5 mm

IA1: stromal invasion <3mm in depth
IA2: stromal invasion ≥3mm and <5mm in depth

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6
Q

Staging for Cervical Cancer (FIGO 2018)

Stage IB

A

IB: invasive carcinoma with measured deepest invasion ≥5mm, lesion limited to cervix

IB1: ≥5mm depth of stromal invasion, <2 cm
IB2: ≥2cm, <4cm in greatest dimension
IB3: ≥4cm in greatest dimension

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7
Q

Staging for Cervical Cancer (FIGO 2018)

Stage II (A and B)

A

Stage II: Carcinoma invades beyond uterus but not to pelvic wall or lower third of vagina
IIA: involvement limited to upper two thirds of vagina without parametrial involvement

IIA1: invasive carcinoma <4cm in greatest dimension
IIA2: invasive carcinoma ≥4cm in greatest dimension
IIB: with parametrial involvement, but not up to the pelvic wall

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8
Q

Staging for Cervical Cancer. (FIGO 2018)

Stage III

A

Stage III: carcinoma involves the lower third of the vagina and/or extends to the pelvic wall and/or causes hydronephrosis or non-functioning kidney and/or involves pelvic and/or para-aortic LNs

IIIA: carcinoma involves the lower third of the vagina, with no extension to pelvic wall
IIIB: Extension to the pelvic wall and/or hydronephrosis or non-functioning kidney (unless known to another cause)
IIIC: Involvement of pelvic and/or para-aortic LNs, irrespective of tumor size and extent
IIICr (LN metastasis on imaging) or IIICp (LN metastasis on pathology)

IIIC1: Pelvic LN only
IIIC2: Para-aortic LN metastasis
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9
Q

Staging for Cervical Cancer (FIGO 2018)

Stage IV

A

Stage IV: extends beyond true pelvis or invades (biopsy proven) the mucosa of bladder or rectum

IVA: spread to adjacent pelvic organs
IVB: Spread to distant organs

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10
Q

Staging for Endometrial Cancer (FIGO)
Stage 1
(T1 for TNM)

A

Stage 1: tumor confined to corpus uteri, including cervical endocervical glandular involvement

IA (T1a): tumor limited to endometrium, invades <50% of myometrium

IB (T1b): Invades ≥ 50% myometrium

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11
Q

Staging for Endometrial Cancer (FIGO)

Stage II (T2)

A

Stage II (T2): Tumor invades stromal connective tissue of the cervix but does not extend beyond uterus (not including endocervical glandular involvement)

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12
Q

Staging for Endometrial Cancer (FIGO)

Stage III (T3)

A

Stage III (T3) - Tumor involving serosa, adnexa, vagina, or parametrium

IIIA (T3a) - tumor invades serosa, adnexa by direct extension or metastasis
IIIB (T3b) - vaginal involvement (direct extension or metastasis) or parametrial involvement
IIIC1 (N1)- metastatic to pelvic lymph nodes
(N1 mi)- LN mets >0.2 mm, <2mm in diameter
(N1a)- LN metastasis >2 mm in diameter
IIIC2 (N2)- metastatic to para-aortic lymph nodes
(N2 mi)- LN mets >0.2 mm, <2mm in diameter
(N2a)- LN metastasis >2 mm in diameter

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13
Q

Staging for Endometrial Cancer (FIGO)

Stage IVA (T4)

A

Stage IVA- Tumor invades bladder mucosa and/or bowel mucosa

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14
Q

Staging for Endometrial Cancer (FIGO)

Stage IVB (M1)

A

Stage IVB (M1): Distant metastasis including inguinal lymph nodes, interaperitoneal disease, lung, liver, or bone

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15
Q

Staging for Carcinoma of the Ovary (FIGO)

Stage I

A

Stage I: Tumor limited to ovaries or fallopian tubes
IA: Tumor limited to one ovary with capsule intact or fallopian tube, no tumor on ovarian or fallopian tube surface, no malignant cells in washings
IB: both ovaries with capsules intact or fallopian tubes, no tumor on surface, no malignant cells on washings
IC: limit to one or both ovaries with the following:
IC1: surgical spill
IC2: capsule ruptured before surgery or tumor on surface of ovaries/fallopian tubes
IC3: malignant cells in ascites or peritoneal washings

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16
Q

Staging for Carcinoma of the Ovaries (FIGO)

Stage II

A

Stage II: tumor involves one or both ovaries, fallopian tubes with pelvic extension below pelvic brim, or primary peritoneal cancer

Stage IIA: extension or implants on the uterus/ fallopian tubes and/or ovaries
Stage IIB: extension to or implants on other pelvic tissues

17
Q

Staging for Carcinoma of the Ovaries (FIGO)

Stage III

A

Stage III: Tumor involves one or both ovaries, fallopian tubes or primary peritoneal cancer with microscopically confirmed peritoneal metastasis outside the pelvis and/or metastasis to retroperitoneal (pelvic and/or para-aortic) LNs

Stage IIIA:

             1: positive LNs only 
              1i: mets ≤10 mm in dimension
              1i: mets > 10 mm in dimension 
             2: microscopic extrapelvic peritoneal involvement  +/- positive retroperitoneal LNs

Stage IIIB: macroscopic peritoneal metastasis beyond pelvis ≤2 cm in greatest dimension +/- metastasis to retroperitoneal LNs

Stage IIIC: peritoneal metastasis beyond pelvis ≥2 cm in dimension +/- retroperitoneal LNs (includes capsule of liver/ spleen without involvement of parenchyma)

18
Q

Staging for Carcinoma of the Ovaries (FIGO)

Stage IV

A

Stage IV: Distant metastasis (not including peritoneal metastasis)

IVA: pleural effusion with positive cytology

IVB: Liver of splenic parenchymal metastases, inguinal LNs, LNs outside of abdominal cavity, transmural involvement of intestine

19
Q

Vulvar Cancer (FIGO)

Stage I

A

Stage I: tumor confined to vulva or perineum

IA: tumor ≤2cm and stromal invasion <1mm
IB: size >2cm or any size with >1mm invasion

20
Q

Vulvar Cancer (FIGO)

Stage II

A

Stage II: tumor of any size with adjacent spread (1/3 lower urethra, 1/3 lower vagina or anus), negative nodes

21
Q

Vulvar Cancer (FIGO)

Stage III

A

IIIA: 1-2 LN metastasis each <5 mm
IIIB: ≥3 LN metastases each <5 mm
IIIC: LN metastases with extracapsular spread

22
Q

Vulvar Cancer (FIGO)

Stage IV

A

Stage IVA: tumor of any size with any of the following: upper 2/3 urethra, upper 2/3 vagina, bladder mucosa or rectal mucosa or fixed to pelvic bone

Stage IVB: distant metastasis including pelvic LN