Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CLINICAL YR: Womens Health > GYN: Neoplasms 10% > Flashcards

GYN: Neoplasms 10% Flashcards

1
Q

(SmartyPance)

third most common type of cancer =

A

cervical cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

(SmartyPance)

postmenopausal abnormal VAGINAL bleeding….think:

A

cervical carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

(SmartyPance)

up to 80% of pts with cervical cancer present with

A

abnormal vaginal bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

(SmartyPance)

postcoital bleeding ddx should include

A

cervical carcinoma

“up to 80% of pts present with abnormal vaginal bleeding, mc postmenopausal…10% note postcoital bleeding”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

(SmartyPance)

location of cervical carcinoma (location and name of zone)

A

squamocolumnar junction of the cervix

transformational zone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

(SmartyPance)

80% of cervical carcinomas are what kind of cells?

A

squamous cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

(SmartyPance)

5 RF for cervical carcinoma

A

multiple sexual partners
early age at first intercourse
early first pregnancy
HPV positive

cigarette smoking association

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

(SmartyPance)

99% of the reason for cervical cancer

A

HPV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

(SmartyPance)

what types of HPV cause cancer? which two especially?

A

16
18
31
33

especially 16 and 18
HPV 16 accounting for approximately 50% of cases and HPV 18 for 20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

(SmartyPance)

what physical exam finding is suspicious for cervical carcinoma?

A

friable
bleeding
cervical lesion on exam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

(SmartyPance)

definitive means of diagnosis for cervical carcinoma

A

biopsy of gross lesions

colposcopically directed biopsies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

(SmartyPance)

what is the treatment for cervical carcinoma?

A

resect
and/or
chemotherapy and radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

(PPP 361)

stage IA1 tx for cervical carcinoma

A

total hysterectomy, radical hysterectomy, conization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

(SmartyPance)

Stage 2 tx for cervical carcinoma

A

chemo +/- radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

(SmartyPance)

5-Year Survival rates for each of the 4 stages of cervical cancer

A

Stage 1: 85-90%

Stage 2: 65%

Stage 3: 29%

Stage 4: 21%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

(SmartyPance)

who gets pap smear screening before the age of 21?

A

women who have HIV infection, at the time of initial intercourse

women who are on chronic immunosuppressive therapy for SLE or post organ transplantation, at the time of initial intercourse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

(SmartyPance)

what kind of pap smear screening is done for women 30 yrs and older? and how often?

A

cytology + HPV testing

every 5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

(SmartyPance)

who gets pap smear screening annually?

A

high-risk groups (HIV infection, immunosuppression, or in utero DES exposure)

women who have been treated in past for CIN 2, CIN 3, or cervical cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

(SmartyPance)

ACOG recommendations for d/c of pap smear screening (two)

A

1 - no cytology screening after total hysterectomy if surgery for benign condition

2 - d/c screening at age 65 yrs for women who have had adequate recent screening
(3 consecutive negative cytology tests or two consecutive negative HPV/pap co-tests in 10 yrs before stopping, w/ most recent test w/in 5 yrs)

20
Q

(SmartyPance)

three types of pathology found on pap screening report

A

ASC-US = Atypical Squamous Cells of Undetermined Significance

LSIL = Low-grade Squamous Intraepithelial Lesion (that is, mild dysplasia, CIN 1)

HSIL = High-grade Squamous Intraepithelial Lesion (that is, moderate to severe dysplasia, CIN II - III, carcinoma in situ)

21
Q

(SmartyPance)

HPV types ___, ___, and ___ are risk factors for cervical dysplasia, which can lead to cervical CA.

A

16, 18, and 31

22
Q

(SmartyPance)

what should be done for women with negative cytology and HPV POSITIVE on pap screening?

A

both tests repeated in 12 months

23
Q

(SmartyPance)

ASCUS and up require ______

A

reflex HPV testing

if negative, can repeat in 12 months; if + then send for colposcopy

24
Q

(SmartyPance)

ASCUS or LSIL, CIN-1 reflex HPV: what to do if +? what to do if -?

A

if positive and at least 25 yrs old =
colposcopy

if negative or under 25 yrs old =
retest in 1 year

25
Q

(SmartyPance)

HSIL, CIN-2, CIN-3, CIS: next steps if outside cervix? if inside cervix?

A

colposcopy

outside cervix –> LEEP or cryotherapy

inside cervix –> cone biopsy

26
Q

(SmartyPance)

squamous cell carcinoma found on pap…next steps?

A

resect
and/or
chemo and radiation

27
Q

(SmartyPance)

which HPV vaccination is available in the US?

A

only the 9-valent

“in the United States, only the 9-valent vaccine is available”

(protects against 90% of warts, 73% of cervical cancers)

28
Q

(SmartyPance)

what does quadrivalent HPV vaccine target?

A

6
11
16
18

29
Q

(SmartyPance)

what does 9-valent HPV vaccine target?

A

6
11
16
18

31
33
45
52
58
30
Q

(SmartyPance)

when is HPV vaccine recommeded for females and males? what’s earliest it can be administered?

A

11-12 yrs

9 yrs (it can be administered starting at 9 yrs of age)

31
Q

(SmartyPance)

what are the recommendations for the HPV catch up vaccination?

A

catch up vaccination is recommended for females aged 13-26 yrs who have not been previously vaccinated or who have not completed the vaccine series

32
Q

(SmartyPance)

HPV vaccination - what do clinicians do with adults 27 thru 45 yrs?

A

for adults ages 27 - 45 yrs, clinicians can consider discussing HPV vaccination with people who are most likely to benefit

33
Q

(SmartyPance)

what is recommended for males for catch-up vaccination for HPV?

A

Among males 22 to 26 yrs old, catch-up HPV vaccination is recommended if they are
MSM
or
immunocompromised (including HIV)

34
Q

(SmartyPance)

HPV vaccination dosing for <15 yrs old:

A

administer two-, rather than a three-dose vaccine series

in such pts, the two doses are administered at least 6 months apart

35
Q

(SmartyPance)

dosing of HPV vaccination for pts >15 yrs old

A

HPV vac is administered in 3 doses at 0, at 1 to 2 months, and at 6 months

36
Q

(SmartyPance)

how many doses of HPV vaccination do immunocompromised pts get?

A

three-dose series

37
Q

(SmartyPance)

how common is vaginal cancer?

A

rare
1% of gynecological malignancies
(usually secondary to other cancer)

38
Q

(SmartyPance)

most common cause of vaginal cancer?

A

squamous cell cancer represents 95%

caused by HPV

39
Q

(SmartyPance)

MC location of vaginal carcinoma

A

upper one-third of posterior vaginal wall

40
Q

(SmartyPance)

typical presentation of vaginal cancer

A

usually presents as changes in menstrual period
and/or
abnormal vaginal bleeding

41
Q

(SmartyPance)

treatment of vaginal cancer

A

radiation therapy

42
Q

(RR)

“what condition should be a pt be evaluated for when presenting with postcoital bleeding?”

A

“cervical cancer”

43
Q

(SmartyPance)
“A 52 year-old obese patient with persistent heavy menses undergoes an endometrial biopsy and is diagnosed with atypical adenomatous hyperplasia. What is the next step in the management of this patient?”

A

total abd hysterectomy

“Atypical adenomatous hyperplasia contains cellular atypia and mitotic figures in addition to glandular crowding and complexity. This has a 20-30% risk of progression to endometrial cancer and the recommendation is hysterectomy.”

44
Q

(PPP 361)

management of STAGE 0 cervical cancer (carcinoma in situ)

A

EXCISION PREFERRED (LEEP, cold knife conization) or ABLATION

can consider total abd hysterectomy + bilateral salpingo-oophorectomy

45
Q

(RR)

what is Paget disease of the vulva?

A

also known as extramammary Paget disease, is a rare vulvar malignancy most commonly seen in women aged 60 to 80

MC presenting s/s is vulvar pruritis

(well-demarcated, slightly raised, erythematous vulvar lesion with an eczematoid appearance)

46
Q

(RR)

what is treatment for Paget Disease of the Vulva?

A

wide local excision with 2 cm margins or vulvectomy

CLINICAL YR: Womens Health (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions