Gyn 1 Flashcards
What are the primordial germ cells derived from?
Epiblast
Primordial germ cells are the precursors to gametes and originate from the epiblast layer during embryonic development.
What is the process by which oogonia divide?
Mitosis
Oogonia undergo mitosis to increase in number before entering meiosis.
At what stage does the primary oocyte get arrested?
Diplotene stage of meiosis prophase
The primary oocyte remains arrested in this stage until puberty.
What resumes the meiosis of the primary oocyte?
Luteinizing Hormone (LH)
The resumption of meiosis occurs at puberty, triggered by hormonal changes.
What is the fertilizable span of an ovum?
12-24 hours
This is the time frame during which fertilization can occur after ovulation.
What is the size of a mature follicle?
8-10 mm (up to 17 mm)
Mature follicles are essential for ovulation and vary slightly in size.
What is the maximum number of follicles present at 5 months of intrauterine life?
6-7 million
The number of follicles decreases significantly by birth.
How many follicles are present at birth?
1-2 million
This number reflects a significant loss from the maximum observed in utero.
What is the main hormone in the first half of the menstrual cycle?
Estrogen
Estrogen plays a crucial role in the proliferative phase of the menstrual cycle.
What effect does estrogen have on FSH?
Negative feedback
Estrogen inhibits FSH secretion to regulate the menstrual cycle.
What initiates the LH surge before ovulation?
Estrogen
The LH surge is critical for triggering ovulation.
What maintains the LH surge?
Estrogen and progesterone
Both hormones play a role in sustaining the LH surge post-ovulation.
What are the two phases of the menstrual cycle?
Follicular phase and luteal phase
These phases correspond to the pre-ovulation and post-ovulation periods in the menstrual cycle.
Fill in the blank: The size of an ovum is ______.
120 microns
This measurement reflects the average diameter of a human ovum.
True or False: The secondary oocyte is arrested in metaphase of meiosis II.
True
The secondary oocyte remains arrested until fertilization occurs.
LH lutenises granulosa cell to form ?
Progesterone
Gynaecology Revision 1
progesterone :
main → Estrogen
Released by luteinised granulosa cells
→ Inhibin B.
Responsible for LH & FSH surge.
FSH
lutenises
LH
release
maink
Estrogen (E2)
Granulosa cell
Theca cell
Progesterone