Gustation

Question 1

what are the 5 tastes?

Answer 1

sweet, sour, umami, salty, bitter

Question 2

what is umami?

Answer 2

glutamate

savoury/ meaty taste

Question 3

what’s different about type II/III neurons to normal neurons?

Answer 3

no dendrites/axons

no APs

Question 4

what is Type I cell?

Answer 4

a glial cell

Question 5

what channels are working in Type II and III neurons?

Answer 5

sodium potassium exchange- pulling potassium in and pushing sodium out
potassium leak- allows K+ out to establish potential

Question 6

what tastes do type III detect?

Answer 6

sour

Question 7

what do type II detect?

Answer 7

sweet, umami, bitter

Question 8

what type of receptor is used by type II cells?

Answer 8

GPCR

Question 9

give the general chain of events when ligand binds GPCR in type II cell

Answer 9

G-alpha dissociates from GDP and binds GTP
this causes it to dissociate from B/y to form 2 subunits
GB/y subunit activates phospholipase C
which activates IP3
IP3 binds IP3