Guillain-Barre Syndrome Flashcards
1
Q
Differential diagnosis of acute ascending motor paralysis
A
Diphtheria Polio Polyarteritis Nodosa Acute intermittent porphyria Tick or snake bites Rhabdomyolysis Arsenic poisoning Botulism
2
Q
Differential diagnosis of autonomic neuropathy
A
Diabetes
Alcoholism
Acute intermittent porphyria
Amyloidosis
3
Q
Triggers for GBS
A
Campylobacter CMV Mycoplasma Zoster HIV EBV Vaccination Intercurrent malignancy (e.g. Hodgkin’s disease) SLE Recent surgery
4
Q
Investigations for GBS
A
Immune stimulus
CSF - raised protein + lack of white cells
RFTs
Nerve conduction & EMG - slowed conduction
Anti-ganglioside antibodies - anti-GM1 & anti-GD3 & anti-GQ1b antibodies are found in 90% of the Miller Fisher variant
5
Q
Miller Fisher Syndrome
A
Opthalmoplegia, ataxia & areflexia
Anti-GQ1b antibodies in the serum
