GU Survey Exam 3 Flashcards
What are the 2 functions of the testes?
- produce sperm
2. secrete hormones (testosterone)
What is in the scrotum?
testicles
What is the function of the scrotum?
- contains the testi at a lower temperature to allow for optimal sperm production
- prone to injuries
Testicular or Scrotal mass? firm solid and 1. painless 2. do not transilluminate 3. usually malignant
testicular mass
Testicular or Scrotal mass?
- painful
- transilluminate
- usually benign
scrotal mass
Are testicular masses usuaslly painful?
no, painless
Will testicular masses transilluminate?
no, do not transilluminate
are testicular masses usually benign or malignant?
usually malignant
are scrotal masses and those in the epididymiss or spermatic cord usually painful?
yes painful
Will scrotal masses and those in the epididymiss or spermatic cord transilluminate?
yes
are scrotal masses and those in the epididymiss or spermatic cord usually malignant or benign?
benign
what tissue/part of the penis is the erectile tissue?
corpora cavernosa
What tissue/part of the penis contains the urethra?
corpus spongiosum
what layer of tissue surrounds the erectile tissue?
tunica albuginea
define circumcision
surgical removal of the foreskin of the penis
is the american academy of pediatrics in support of circumcision?
Yes, as a result of emerging evidence that found links between circumcision and decreased risk of urinary tract infection, rare penile cancer, HPV, HIV and other STIs, the AAP is in more support of the procedure
Does the AAP recommend routine circumcision for all newborn males?
no, “What remains unchanged is that the AAP still holds that the
health benefits are not great enough to recommend routine
circumcision for all newborn males,”
what are 3 non medical reasons PRO circumcision?
- religious/faith
- aesthetics
- hygiene
what are 2 possible medical advantage of circumcision?
- less UTI, STI/HIV
2. less risk of penile cancer
What are 5 cons/surgical risks to infant of circumcision?
- hemorrhage
- infection
- pain/trauma
- diminshed sensation
- > mother/child bonding
where are the seminal vesicles located?
out-pocketing of vas deferens: extend from base of bladder
what does the seminal vesicles and vas deferens form?
ejaculatory duct
what is the order of sequency from the seminal vesicles?
- extend from base of bladder, out pocketing of vas deferens –> forms ejaculatory duct –> thru prostate –> to urethra
what is secreted from the seminal vesicles?
70% of fluid components of semen = energy/fluidity for sperm
secretions from where supply 70% of fluid for semen and provide the energy for sperm?
seminal vesicles
HPO axis for tesis?
hypothalamus > GnRH > pituitary > LH and FSH
what does LH in the testis stimulate?
leydig cells to produce testosterone
what cells produce testosterone?
leydig cells/interstitial cells
testosterone + FSH =>
spermatogenesis
how many sperm does a male produce each day?
70-100 million each day!
length of time for production of spermatogenesis in the testes?
approx 70 days
length of time for maturation of sperm in the epididymis?
= 2 weeks
what 3 components occurs as part of the maturation of sperm in the epididymis?
acquisition of
- motility
- capacity to bind to an ovum
- capacity to penetrate the zona pellucida
after what age should FOBT x3 be used as lab work up for preventative health?
after age 50
what is the peak age for tumors for penile conditions?
60 YO
what parts to the penis are tumors likely to involve (2)?
prepuce or glans
dx?
painless, enlarging wart-like growth
HPV, conyloma acuminata
dx?
hyperkeratotic, scaly, white patches of penile epithelium, yes for biopsy?
leukoplakia
is a biopsy necessary if you suspect leukoplakia?
yes
dx? an intraepidermal (pre)cancerous indurated erythematous plaque, ulcerated center, development of pinkish or brownish papules covered with a thickened horny layer
Bowen’s dz
is a biopsy necessary for bowen’s dz?
yes
what are 2 skin cancers of the penis?
squamous cell carcinoma, SCC
and
melanoma
what is balanitis
inflammation of glans
Causes of balanitis? (8)
1. Uncircumcised w/ poor hygiene or over hygiene 2. Diabetes 3. Chemical irritants 4. CHF, cirrhosis, nephrosis 5. Drug allergies 6. Obesity 7. Infections: candida, HPV, anaerobes, treponema, gardnerella, tichomonas 8. Penile cancer
what is phimosis?
In ability to retract the distal foreskin.
-at birth the foreskin is adherent to the glans penis. These adhesions usually spontaneously separate and allow the foreskin to become retractible.
what is paraphimosis?
Paraphimosis is the entrapment of a retracted foreskin behind the coronal sulcus. Paraphimosis is a disease of uncircumcised or partially circumcised males.
where is the urethral opening with hypospadius
urethral opening on the ventral surface
which side is the ventral surface of the penis?
under
which is more common hypospadius or epispadius?
hypospadius
what is it called when the urethral opening is on the dorsal surface of the penis?
epispadius
which side is the dorsal surface of the penis?
upper
What are 3 causes of hypospadius and epispadius?
- exposure to PG hormone, finesteride
- lack of T in utero
- inherited
what is hypo and epispadius often associated with? (2)
- inguinal hernias
2. cryptorchidism
what is priapism?
non-erotic sustained painful erection with acute onset
why does the glans remain soft with priapism?
glans remains soft because involves the corpora cavernosa but not the spongiosum
Etiology of priapism?
- unknown in most cases
- possible associated w/ leukemia, metastatic carcinoma, local trauma, sickle cell dz, spinal cord trauma, circulatory distrubances, medications like viagra
tx for priapism? (5)
- spontaneously resolve in few hours
- ice water
- enema
- pharmaceutical intervention
- drainage is rare cases
dx?
plaques/strands of dense fibrous tissue surrounding the corpus cavernosum –> deformity and painful erection, impotence
peyronie’s dz
what are the s/sx of peyronie’s dz?
- hardened tissue
- pain during erection
- curvature with erection
- distortion (indentation, shortening)
most common age for peyronie’s dz?
45-60 YO
etiology/risk factors for peyronie’s dz? (5)
- unknown
- trauma (surgery, injury)
- HLA-B7 (SLE. Scleroderma)
- 30% of ppl will develop fibrotic tissue in other areas like dupuytrens contracture
- diabetics
how do you dx peyronie’s dz?
exam and vasoactive injection to cause erection
tx for peyronie’s dz? (3)
- watch and wait 1-2 years, often resolves
- non surgical tx within 6 mnths of dx: ca+ channel blockers, collagenase, cortisone
- surgery
- severe/persistent
- can cause partial loss of erectile function, penis length, urethral damage, infection, sensation loss
penile cancer incidence?
1/100k USA
what percentage of malignancies in men is d/t penile cancer?
0.2%
how much higher is cervical cancer incidence than penile cancer?
10x higher
how much higher is prostate cancer incidence than penile cancer?
100x
how much higher is fatal heart attack incidence than penile cancer?
200x
what are 3 sx of penile cancer?
- penile growths or sores
- abnormal penile d/c
- bleeding
what area is the most common site for penile cancer?
glans and foreskin
Risk factors for penile cancer? 4)
- intact/non-circumcised male (high risk factor, low incidence)
- HPV infection (only certain strains, low risk factor)
- smoking
- age: majority >50 YO (40% <40 YO)
chance for penile cancer in uncircumcised vs circumcise?
un- 1/600
circumcised- 1/1500
what are the 3 main tx for penile cancer?
- surgery: excision, laser, circumcision, partial to complete penectomy, nodal dissection
- radiation
- chemotherapy: topical, oral/IV
What are some examples of surgical procedures for treatment of penile cancer?
- excision
- laser
- circumcision
- partial to complete penectomy
- nodal dissection
what is the most common reason for visit to a urologist?
scotal masses
define a scrotal mass?
painless or painful lump or swelling
can scrotal masses be solid or cystic?
yes
can you develop a scrotal mass at any age?
yes
how are scrotal masses evaluated?
via US
how do most men discover scrotal masses?
most men discover scrotal masses themselves
Describe a testicular exam
- stand in front of mirror
- examine each testicle with both hands
- gently roll the testicle between the thumbs and fingers
- if palpable lump, refer for US and/or a urologist
what are 5 causes of scrotal masses?
- cysts
- infection
- inflammation
- hernia
- tumors
what is cryptorchidism?
undescended testicles
what is a 30% risk with preterm infants?
undescended testicles
what are 3 risks associated with crytorchidism ?
- testicular cancer
- infertility
- torsion
what are the two location for the testicle for cryptorchidism?
- abdominal testicle
2. pubo-scrotal testicle
what are the two location for ectopia undescended testicle?
- femoral
2. perineal
ddx?
worse with lifting the testicle
testicular torsion
ddx epididmyitis- pain lessens
describe the sx of testicular torsion?
- sudden severe pain, swelling, erythema
2. lower ab pain, N/V
dx? 1. sudden severe pain, swelling, erythema 2. lower abdominal pain, N/V 3. worse with lifting the testicle
testicular torsion
Is testicular torsion considered a medical emergency?
yes
within how many hours should surgery for testicular torsion occur?
6-8 hrs to prevent atrophy, 80% good prognosis
after how many hours is preservation of the testicle doubtful in relationship to testicular torsion?
24 hrs
what type of surgery is advised if delayed beyond 48 hr?
orchiectomy
does pain get worse or better with lifting of testicle with epididymitis?
pain lessens
what is a hydrocele?
collection of fluid in the sheath (tunica) that holds the testicle
Cause of hydrocele?
excess fluid production or decreased fluid absorption
is a hydrocele painful?
often painless
will hydrocele be transilluminated?
yes
describe a hydrocele?
often painless, swollen, soft, unilateral or bilateral, that will transilluminate
what is the ddx for hydrocele?
varicocele
younger or older men more likely to have hydrocele?
older
can hydrocele develop rapidly?
yes
causes of hydrocele?
- trauma
- radiation therapy
- inflammation
- congenital
“bag of worms”
varicocele
what causes a varicocele?
blood backs up in the veins leading from the testicles d/t valve dysfunction
varicocele painful or painless?
painless