Growth And Its Dis Flashcards

1
Q

Inhibitory factors of growth?

A

Tgf-beta
Mullerian inhibiting substance
Activin /inhibin

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2
Q

Genetic ass of which organs?

A

Head
Chest
Fatty tissues

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3
Q

Retardation of growth seen in

A

Turner syndrome
Noonan syndrome
Prader wili syndrome
Down syndrome

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4
Q

Tall stature

A

Klinefelter syndrome

Sotos syndrome

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5
Q

Barkers hypotheses or fetal origins hypothesis?

A

The alterations in fetal nutrition and endocrine status result in developmental adaptations that permanently change structure, physiology and metabolism, and so predisposing individuals to cardiovascular, metabolic and endocrine dis in adult life. As a result infants with LBW,have inc risk of DM, HTN, CAD and hyperlipidemia in adult life

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6
Q

Body growth is rapid during?

A
  • fetal life (first half of gestation)
  • first one or two years of postnatal life
  • during puberty
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7
Q

Order of growth?

A

Cephalocaudal and distal to proximal

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8
Q

Fetus?

A

9weeks to birth

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9
Q

Embryo?

A

14 days of gestation to 9weeks

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10
Q

Mc pathological cause of short stature?

A

Malnutrition

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11
Q

Mc physiological cause of short stature?

A

Constitutional short stature

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12
Q

Greulish and pyles method?

A

X ray of hand and wrist taken to find bone age using left hand

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13
Q

Tanner and whitehouse method?

A

Multiple X-rays all over the body to find bone age

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14
Q

In infants between 3m to 9m, age by?

A

Shoulder X-ray

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15
Q

In childhood, between 1y to 13y age by?

A

Hand and wrist X-ray

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16
Q

Between 12-14y age by?

A

Elbow and hip X-ray

17
Q

Pisciform appears at?

A

10-13y

18
Q

Capitate at?

A

2m

19
Q

Hamate at

A

Between 2m-2y

20
Q

Distal ulnar epiphysis at

A

8-12y

21
Q

Lesser trochanter at

A

12y

22
Q

Iliac crest at

A

16y

23
Q

Age dependent markers for growth assessment

A

Ht
Wt
Head circumference

24
Q

Age independent markers for growth assessment

A

Mid arm circumference

Skin fold thickness