Growth And Its Dis Flashcards
Inhibitory factors of growth?
Tgf-beta
Mullerian inhibiting substance
Activin /inhibin
Genetic ass of which organs?
Head
Chest
Fatty tissues
Retardation of growth seen in
Turner syndrome
Noonan syndrome
Prader wili syndrome
Down syndrome
Tall stature
Klinefelter syndrome
Sotos syndrome
Barkers hypotheses or fetal origins hypothesis?
The alterations in fetal nutrition and endocrine status result in developmental adaptations that permanently change structure, physiology and metabolism, and so predisposing individuals to cardiovascular, metabolic and endocrine dis in adult life. As a result infants with LBW,have inc risk of DM, HTN, CAD and hyperlipidemia in adult life
Body growth is rapid during?
- fetal life (first half of gestation)
- first one or two years of postnatal life
- during puberty
Order of growth?
Cephalocaudal and distal to proximal
Fetus?
9weeks to birth
Embryo?
14 days of gestation to 9weeks
Mc pathological cause of short stature?
Malnutrition
Mc physiological cause of short stature?
Constitutional short stature
Greulish and pyles method?
X ray of hand and wrist taken to find bone age using left hand
Tanner and whitehouse method?
Multiple X-rays all over the body to find bone age
In infants between 3m to 9m, age by?
Shoulder X-ray
In childhood, between 1y to 13y age by?
Hand and wrist X-ray