Growth Flashcards

1
Q

Growth regulations

A
  • GH from AP
  • Thyroid hormones
  • Insulin
  • Sex steroids
  • Nutrient availability
  • Stress
  • Genetics
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2
Q

GH regulators

A
  • GHRH

- GHIH

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3
Q

GH

A

Peptide hormone secreted by AP and transported by carriers

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4
Q

Indirect effect of GH

A

IGF-1 secreted by liver (and other cells) in response to GH.
(GH; Precondrocytes -> condrocytes)
- IGF-1 secreted; autocrine/paracrine agent. Condrocytes differentiate and produce cartilage.

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5
Q

Direct effect of GH

A

Utilise energy for growth

  1. Increases gluconeogenesis
  2. Inhibits insulin uptake
  3. Promotes lipolysis
  4. Increases AA uptake and protein synthesis (anabolic)
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