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CHEMOTHERAPY > Groups > Flashcards

Groups Flashcards

1
Q

Prodrugs (8)

A

Prodrugs:

  1. Allopurinol
  2. Azathioprine (6MP)
  3. Cyclophosphamide (4-OHCytoxan)
  4. Dexrazoxane (hydrolysis)
  5. Ifosfamide
  6. Irinotecan (SN-38)
  7. Fludarabine
  8. Mitomycin C
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2
Q

Radiosensitizers (9)

A

Radiosensitizers:

  1. Adriamycin (of normal tissue - can’t use!)
  2. Bleomycin (synergism if use 3h bf or after)
  3. cisplatin
  4. Dactinomycin
  5. Etoposide
  6. Mitoxantrone
  7. Mitomycin C
  8. Taxanes (in vitro)
  9. Vincas
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3
Q

Which of the following are cell phase non-specific?

Elspar
Bleomycin
Melphalan
Vincristine
Taxol
Chlorambucil
Vinorelbine
Cytoxan
Busulfan
A 
Elspar
Bleomycin
Melphalan
Chlorambucil
Cytoxan
Busulfan
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4
Q

The vincas and taxanes are specific for which of the following phases?

  1. S phase
  2. G2/M
  3. G1
A

G2/M

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5
Q

Which of the following are cell phase non-specific?

Elspar
Bleomycin
Melphalan
Vincristine
Taxol
Chlorambucil
Vinorelbine
Cytoxan
Busulfan
A 
Elspar
Bleomycin
Melphalan
Chlorambucil
Cytoxan
Busulfan
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6
Q

The vincas and taxanes are specific for which of the following phases?

  1. S phase
  2. G2/M
  3. G1
A

G2/M

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CHEMOTHERAPY (12 decks)

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