Group carriers- L10 + 11 (M3+4) Flashcards
1
Q
What is the carrier for C1 (methyl) ?
A
S-adenosylmethionine (SAM)
SAM -> S- adenosylhomocysteine -> homocysteine -> methionine ->
2
Q
What is the carrier for C2 (acetyl)?
A
Coenzyme A
Attaches to sulfur on thioester group
3
Q
Why does having a thioester group make a good carrier?
A
Thioester more unstable than ester group
Makes transfer of acetyl easier
4
Q
Examples of when CoA is used
A
Fatty acid biosynthesis
Link reaction (pyruvate -> acetyl CoA fed into kreb cycle)
5
Q
What is the carrier for C5?
A
Isopentenyl pyrophosphate
6
Q
What is C5 made from?
A
3x acetyl CoA molecules (C6)
mevalonate -> phosphomevalonate -> pyrophosphomevalonate -> isopentenyl pyrophosphate
